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2,000 results for “cardiac surgery”
Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit
ClinicalTrials.gov study NCT06154473. IPD Sharing: YES. Countries: 1. Publications: 1.
Inhibition of Lipid Peroxidation During Cardiac Surgery
ClinicalTrials.gov study NCT01366976. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Patient Mobility and Outcomes After Cardiac Surgery
ClinicalTrials.gov study NCT03806257. IPD Sharing: NO. Countries: 1. Publications: 1.
Risk of Oxygen During Cardiac Surgery Trial
ClinicalTrials.gov study NCT02361944. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Impact of Prontosan Wound Gel X on Surgical Site Infections in Cardiac Surgery
ClinicalTrials.gov study NCT07275307. IPD Sharing: NO. Countries: 1. Publications: 21.
Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery
ClinicalTrials.gov study NCT07315308. IPD Sharing: NO. Countries: 0. Publications: 3.
Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies
ClinicalTrials.gov study NCT05279898. IPD Sharing: Not stated. Countries: 1. Publications: 13.
Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS)
ClinicalTrials.gov study NCT00587990. IPD Sharing: NO. Countries: 1. Publications: 1.
Balancing Risk: Red Blood Cell Transfusion Strategies In Cardiac Surgery
ClinicalTrials.gov study NCT00651573. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Glycemic Control to Prevent Cardiac Morbidity in Vascular Surgery
ClinicalTrials.gov study NCT00328094. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Data from: Impact of microRNA expression in human atrial tissue in patients with atrial fibrillation undergoing cardiac surgery
Background: Although microRNA (miRNA) regulates initiation and/or progression of atrial fibrillation (AF) in canine AF models, the underlying mechanism in humans remains unclear. We speculated that certain miRNAs in atrial tissue are related to AF, and evaluated the relationship of miRNA expression in human atrial tissue in cardiac surgery patients. Methods: Right atrial tissues from 29 patients undergoing cardiovascular surgery were divided into 3 groups [A: chronic AF or unsuccessful maze, n=6; B: successful maze, n=10; C: sinus rhythm (SR) n=13]. miRNA expression was determined using high density microarrays and with Reverse transcriptase-polymerase chain reaction (RT-PCR). Fibrosis was examined using Masson trichrome staining. Results: miRNA microarray analysis showed elevated miRNA-21, miRNA-23b, miRNA-199b, and miRNA-208b in AF as compared to SR groups. RT-PCR showed elevated miRNA-21 (1.9-fold) and miRNA-208b (4.2-fold) in AF as compared to the SR groups. miRNA-21 expression increased from Group C to A (A: 2.1-fold, B: 1.8-fold, C: 1.0-fold). Fibrosis increased from C to A (A: 43.0±12.9%, B: 21.3±6.1%, C: 11.9±3.1%). Percent fibrosis and miRNA-21 expression were correlated (r=0.508, p<0.05). The plasma levels of miRNA-21 in AF patients was significantly decreased as compared to the healthy volunteers (p<0.05). Conclusion: The expression of miRNA-21 in human atrial tissue was found to be related to atrial fibrosis and might affect AF occurrence, indicating its usefulness as a biomarker for cardiac surgery management.
Data from: Self-reported functional status predicts post-operative outcomes in non-cardiac surgery patients with pulmonary hypertension
BACKGROUND: Pulmonary hypertension (PHTN) is associated with increased post-procedure morbidity and mortality. Pre-procedure echocardiography (ECHO) is a widely used tool for evaluation of these patients, but its accuracy in predicting post-procedure outcomes is unproven. Self-reported exercise tolerance has not been evaluated for operative risk stratification of PHTN patients. OBJECTIVE: We analyzed whether self-reported exercise tolerance predicts outcomes (hospi-tal length-of-stay [LOS], mortality and morbidity) in PHTN patients (WHO Class I - V) under-going anesthesia and surgery. METHODS AND FINDINGS: We reviewed 550 non-cardiac, non-obstetric procedures per-formed on 370 PHTN patients at a single institution between 2007 and 2013. All patients had cardiac ECHO documented within 1 year prior to the procedure. Pre-procedure comorbidities and ECHO data were collected. Functional status (< or ? 4 metabolic equivalents of task [METs]) was assigned based on responses to standard patient interview questions during the pre-anesthesia clinic visit. Multiple logistic regression was used to develop a risk score model (Pul-monary Hypertension Outcome Risk Score; PHORS) and determine its value in predicting post-procedure outcomes. In an adjusted model, functional status <4 METs was independently associ-ated with a LOS >7 days (p < .003), as were higher ASA class (p < .002), open surgical approach (p < .002), procedure duration > 2 hours (p < .001), and the absence of systemic hypertension (p = .012). PHORS Score ?2 was associated with an increased 30-day major complication rate (28.7% vs. 19.2%; p < 0.001) and ICU admission rate (8.6% s 2.8%; p = .007), but no statistical difference in hospital readmissions rate (17.6% vs. 14.0%; p = .29), or mortality (3.5% vs. 1.4%; p = .75). Similar ECHO findings did not further improve outcome prediction. CONCLUSIONS: Poor functional status is associated with severe PHTN and predicts increased LOS and post-procedure complications in patients with moderate to severe pulmonary hyperten-sion with different etiologies. A risk assessment model predicts increased LOS with fair accura-cy. A thorough evaluation of underlying etiologies of PHTN should be undertaken in every pa-tient.
Copeptin and HFABP in Cardiac Surgery
ClinicalTrials.gov study NCT04877795. IPD Sharing: NO. Countries: 1. Publications: 1.
Descriptive and Comparative Study of Respiratory Function in the Postoperative Cardiac Surgery Patient
ClinicalTrials.gov study NCT03009331. IPD Sharing: NO. Countries: 1. Publications: 2.
High Flow Oxygen Therapy Versus Conventional Oxygen Therapy in Cardiac Surgery Patients
ClinicalTrials.gov study NCT03282552. IPD Sharing: NO. Countries: 1. Publications: 44.
Effect of Heart-lung-machine on Selenium Status of Cardiac Surgical Patients Undergoing Coronary Bypass Surgery
ClinicalTrials.gov study NCT01409057. IPD Sharing: Not stated. Countries: 1. Publications: 1.
VR Training to Improve Postoperative Cognitive Function in Elderly Patients With Cerebral Small Vessel Disease Undergoing Non-Cardiac Surgery
ClinicalTrials.gov study NCT07370844. IPD Sharing: YES. Countries: 1. Publications: 8.
Perioperative Versus Postoperative Glycemia Control in Cardiac Surgery Patients
ClinicalTrials.gov study NCT01548963. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features
ClinicalTrials.gov study NCT00665015. IPD Sharing: Not stated. Countries: 1. Publications: 1.
SEx-specific Differences in Cardiac Surgery Patients (SECS).
ClinicalTrials.gov study NCT06554925. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.