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117
datasets available to search
ShareScore release 0.9.0
Dataset results
117 results for “choroidal neovascularization”
Histone lactylation-mediated NSUN2 transcriptional activation dictates choroidal neovascularization through promoting AKAP2 mRNA expression [CUT&Tag]
GEO Series GSE267661. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Photodynamic Therapy (PDT) Versus Transpupillary Thermotherapy (TTT) in Occult Choroidal Neovascularization (CNV) in Age-related Macular Degeneration (AMD)
ClinicalTrials.gov study NCT00347906. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Comparison Between Home Macular Perimeter and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV)
ClinicalTrials.gov study NCT01336907. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Long-Term Use Of Pegaptanib In Patients For Subfoveal Choroidal Neovascularization Secondary To Age-Related Macular Degeneration
ClinicalTrials.gov study NCT00845273. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Reduced-fluence Verteporfin Photodynamic Therapy Plus Ranibizumab for Choroidal Neovascularization in Pathologic Myopia
ClinicalTrials.gov study NCT01968486. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Study on the Biomarkers of Anti-VEGF Treatment for Choroidal Neovascularization
ClinicalTrials.gov study NCT06243406. IPD Sharing: NO. Countries: 0. Publications: 0.
Ranibizumab Therapy for Choroidal Neovascularization (CNV) Asociated With Angioid Streaks
ClinicalTrials.gov study NCT01015495. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Conbercept in Choroidal Neovascularization Secondary to Uveitis
ClinicalTrials.gov study NCT02934841. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Phase II Study Evaluating the Efficacy of Aflibercept for the Treatment of Choroidal Neovascularization in Angioid Streaks in Young Patients (ASTRID).
ClinicalTrials.gov study NCT02573038. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Anecortave Acetate in Subfoveal Choroidal Neovascularization (CNV) Due to Wet Age-Related Macular Degeneration (AMD)
ClinicalTrials.gov study NCT00051129. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Safety Study of Ranibizumab Eye Injections to Treat Choroidal Neovascularization That Was Caused Other Than by Age-Related Macular Degeneration.
ClinicalTrials.gov study NCT00395551. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Immune Checkpoint PD-L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK
GEO Series GSE282544. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
ALKBH5 induces retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via PIK3C2B/AKT/mTOR pathway
GEO Series GSE212914. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing; Other.
Transcriptional characterization of human and mouse choroidal neovascularization identifies fibroblast growth factor inducible-14 as a novel mediator of neo-vascular age-related macular degeneration
GEO Series GSE163090. Homo sapiens; Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
tRF/tiRNA expression profile of RPE-choroid-sclera complex in the laser-induced choroidal neovascularization mouse model
GEO Series GSE210099. Mus musculus. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
VIDEO COLOR OCT ANGIOGRAPHY FOR MYOPIC CHOROIDAL NEOVASCULARIZATION
<p><strong>Purpose: </strong>To investigate the myopic macular neovascularization (mMNV) features on dynamic video-color optical coherence tomography (OCT) angiography (OCTA) and the diagnostic rate versus the static, four-segmentations visualization mode.</p> <p><strong>Design: </strong>Retrospective cohort study PARTICIPANTS: Fifty-four patients with mMNV METHODS: Sixty-two eyes with high myopia complicated by mMNV were included. Clinical charts, fluorescein angiography and structural OCT were used as standard reference to assess lesion activity. Static and video-color OCTA were then analysed and compared by two independent reviewers.</p> <p><strong>Main outcome measures: </strong>Morphology description of mMNV on video-color OCTA and differences in the proportion of diagnosis between video-colour and static OCTA.</p> <p><strong>Results: </strong>62 eyes from 54 patients (mean age 63,22 years) were enrolled. Thirty-four (55%) mMNV were active and 28 (45%) inactive. Twenty-two (65%) active mMNV presented on video-color OCTA as an interlacing vascular network in the outer retina and the choriocapillaris. A tapered form was the prevalent size (72,7%). In 3 eyes (9%) an abnormal and irregular vascular network (AVN) was disclosed and in 5 (15%) only some blood flow alteration. All the lesions extended both in the outer retinal and the choriocapillaris. Eleven (39%) inactive mMNV presented on video-color OCTA as an interlacing vascular network too, in the outer retina and the choriocapillaris. Eight (29%) had some AVN and 6 (21%) only some blood flow alteration. The diagnostic rate of video-color vs static OCTA was 95% (IC 95% 86% to 99%) vs 77% (IC 95% 86% to 99%, p= 0.0009), and shows an advantage in favour of video-colour OCTA of 15% (CI 95%, 3%-27%) and 22% (CI 95%, 7%-38%) in active and inactive lesions, respectively (p<0.026). Lesion extension within both the outer retina and the choriocapillaris was present in 90% and 69% of cases on dynamic OCTA and static OCTA, respectively, with a proportion difference of 20% (CI 95%, 10%-31%, p= 0.0005). Concordance between the two examiners was high: 0.95 (95%, CI 0.88 to 1.00) and 0.96 (0.91 to 1.00) for active and inactive lesions, respectively.</p> <p><strong>Conclusions: </strong>Video color-enhanced OCTA may help in diagnosing mMNV and should be considered by clinicians in addition to structural OCT and static OCTA.</p> <h3>This set of raw data cannot be made publicly availabe as including sensitive information, but might be made available to interested researchers upon reasonable request. Please, forward your request to: dottpaolomilani@hotmail.com</h3>
Algorithm of the major and minor diagnostic criteria for active myopic choroidal neovascularization
<p>Key Messages:<br> Leakage on fluorescein angiography and hyperreflectivity on SD-OCT are the gold standard diagnostic biomarkers<br> To date, the diagnostic accuracy of several biomarkers has been investigated singularly. However, the totality of biomarkers deriving from clinical and multimodal imaging has not been investigate thoroughly<br> This study proposes an algorithm with a combination of major and minor clinical and imaging parameters<br> identifying a classification tree based on rigorous statistical analysis.for myopic CNV.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.