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260
datasets available to search
ShareScore release 0.9.0
Dataset results
260 results for “inflammatory mediators”
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases
GEO Series GSE125931. Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Electrophilic stress induced by dimethyl itaconate regulates IkB-zeta-mediated inflammatory responses
GEO Series GSE102190. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Difamilast treatment inhibits the expression of inflammatory mediators in bone marrow-derived basophils (BMBAs) stimulated by IL-3 + IL-33
GEO Series GSE234541. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Chronic Psychological Stress regulates Visceral Adipocyte-mediated Glucose Metabolism and Inflammatory Circuits in male Rats
GEO Series GSE47754. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
NINJ1 mediates inflammatory cell death, PANoptosis, and drives lethality during heat stress
GEO Series GSE252609. Mus musculus. 4 samples. Type: Other.
Bromodomain and extra-terminal (BET) inhibitors regulate NK cell biology by inhibiting BRD2 mediated NK cytolytic activity and BRD2/BRD4 mediated inflammatory function
GEO Series GSE156423. Homo sapiens. 64 samples. Type: Expression profiling by high throughput sequencing.
The anti-inflammatory nature of HDL in macrophages is mediated by ATF3
GEO Series GSE44034. Mus musculus. 60 samples. Type: Expression profiling by array.
Loss of tumor suppressors promotes a non-cell-autonomous inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression [RNA_seq_vitro]
GEO Series GSE249971. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide profiling of inflammatory cistrome reveals AP-1/c-Jun as a key regulator of TNFalpha-mediated triple-negative breast cancer progression.
GEO Series GSE71977. Homo sapiens. 16 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
Ptgs2+ Telocytes Mediate M2 Macrophages for Anti-Inflammatory Effects Following Acupuncture in the Abdominal Midline Fascia of Dysenteric Rats
GEO Series GSE271811. Rattus norvegicus. 4 samples. Type: Expression profiling by high throughput sequencing.
NEDD4L mediates intestinal epithelial cell ferroptosis to restrict inflammatory bowel diseases and colorectal tumorigenesis
GEO Series GSE282497. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A pathogenic CD4 T cell phenotype in experimental uveitis shares common features with other immune mediated inflammatory diseases
GEO Series GSE289820. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
NF-κB- and TET2-mediated macrophage reprogramming overrides the anti-inflammatory effects of hypoxia and improves responses in human cancer (DNA methylation I).
GEO Series GSE261317. Homo sapiens. 20 samples. Type: Methylation profiling by array.
NF-κB- and TET2-mediated macrophage reprogramming overrides the anti-inflammatory effects of hypoxia and improves responses in human cancer (RNA-Seq II).
GEO Series GSE261323. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Integrative Epigenome-Wide Analysis Shows That DNA Methylation May Mediate Genetic Risk In Inflammatory Bowel Disease [Cells, Methylation profiling]
GEO Series GSE87640. Homo sapiens. 240 samples. Type: Methylation profiling by genome tiling array.
HIF-alpha signaling mediates the macrophage inflammatory response during Leishmania majorinfection
GEO Series GSE273822. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Data from: Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents development of atherosclerosis in high-fat diet-fed apoE-deficient mice via ameliorating hyperlipidemia, pro-inflammatory mediators and oxidative responses
Pantoea agglomerans (P. agglomerans) is a Gram-negative bacterium that grows symbiotically with various edible plants, and the oral or sublingual administration of lipopolysaccharide derived from P. agglomerans (LPSp) have been suggested to contribute to prevention of immune-related diseases. Our previous study indicated that orally administered LPSp was shown to exhibit an LDL-lowering effect in hyperlipidemic volunteers; however, a preventive effect of LPSp on atherosclerosis is unclear. The present study attempted to evaluate the anti-atherosclerotic effect by LPSp in a mouse model of high-fat diet (HFD)-induced atherosclerosis. For 16 weeks, apoE-deficient mice were fed an HFD and received drinking water containing LPSp (0.3 or 1 mg/kg body weight/day). The results showed that the orally administered LPSp decreased body weight. A significant reduction in atherosclerotic plaque deposition was observed even with the lower dose of LPSp. The biochemical analyses showed that LPSp markedly improved glucose tolerance and reduced plasma LDL and oxidized LDL levels. In addition, LPSp significantly reduced the production of pro-inflammatory mediators including MCP-1 (in the plasma), TNF-α and IL-6 (in the colon), and decreased the oxidative burst activities in the peripheral blood sample. Taken together, these results suggest the possibility that oral administration of LPSp can effectively ameliorate HFD-induced hyperlipidemia and inflammatory/oxidative responses to prevent atherosclerosis and related metabolic disorders.
A Study of Adalimumab on Inflammatory Mediators Following a Systemic Endotoxin Challenge
ClinicalTrials.gov study NCT05884242. IPD Sharing: YES. Countries: 1. Publications: 0.
Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
ClinicalTrials.gov study NCT05732987. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of the Anti-VZV Vaccine Response of Patients With Immune-mediated Systemic Inflammatory Diseases Vaccinated in the Care Setting
ClinicalTrials.gov study NCT07047053. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.