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482 results for “leukocyte”
White Blood Cell: A Dataset for Leukocyte Classification
<p>White Blood Cell Dataset</p>
Data from: Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
Macrophages and neutrophils are the first responders to invading pathogens and contribute strongly to the host defense against intracellular pathogens. The collective interplay and dynamic interactions between these leukocytes are to a large extent not understood. In the present study, we have investigated their role using a combination of confocal laser-scanning and electron microscopy in a zebrafish model for tuberculosis, a local Mycobacterium marinum infection in the tissue of the larval tail fin. Our results show that neutrophils are efficient in phagocytosis of mycobacteria and that they contribute largely to their dissemination. Macrophages appear to play a major role in efferocytosis, phagocytosis of dead cells that contain bacterial content. Phagocytic cells with large bacterial aggregates are formed that can be extruded out of the tissue after cell death. Alternatively, these excessively infected cells can undergo necrosis leading to immediate recruitment of surrounding leukocytes and subsequent phagocytosis of released bacteria. Our data show that these necrotic burst events result in progression of the infection, whereas extrusion abates the infection.
Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine
ClinicalTrials.gov study NCT03615755. IPD Sharing: UNDECIDED. Countries: 0. Publications: 23.
Gene Therapy for Patients With Leukocyte Adherence Deficiency (Follow-Up of Phase 1 Trial)
ClinicalTrials.gov study NCT00023010. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions
ClinicalTrials.gov study NCT01241903. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Quality of Life in Allergic Rhinoconjunctivitis Patients Treated With Dialyzable Leukocyte Extracts
ClinicalTrials.gov study NCT02506998. IPD Sharing: Not stated. Countries: 0. Publications: 1.
CCK1R Function in Patient Leukocytes
ClinicalTrials.gov study NCT03121755. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Clinical Significance of Leukocyte Cell Population Data in Patients with Myeloproliferative Neoplasms (MPNs)
ClinicalTrials.gov study NCT06753279. IPD Sharing: UNDECIDED. Countries: 0. Publications: 3.
A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It
ClinicalTrials.gov study NCT03487718. IPD Sharing: NO. Countries: 1. Publications: 0.
Diagnostic Performance of a Combination of Leukocyte Cell Surface Markers in Predicting the Risk of Severe Bacterial Infection in Febrile Children Under Three Months of Age in the Emergency Department
ClinicalTrials.gov study NCT06618989. IPD Sharing: YES. Countries: 1. Publications: 0.
Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic
ClinicalTrials.gov study NCT02500550. IPD Sharing: NO. Countries: 6. Publications: 0.
Trial to Evaluate Safety and Tolerability of Tacrolimus Extended-Release (Astagraf XL) in Human Leukocyte Antigen (HLA) Sensitized Kidney Transplant Recipients
ClinicalTrials.gov study NCT03194321. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Combination of Leukocyte Cell Surface Biomarkers Measured by Cytometry, to Differentiate Bacterial From Viral Infections in Emergency Department: a Multicentric Cohort for the Validation of Diagnostic
ClinicalTrials.gov study NCT06155266. IPD Sharing: YES. Countries: 1. Publications: 0.
To Compare Ridge Preservation Technique Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-dried Bone Allograft (FDBA) Layered Technique vs L-PRF/FDBA and L-PRF Alone in Influencing Quantity and
ClinicalTrials.gov study NCT04133363. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
Open the record for dataset details and reuse information.
Leukocyte gene expression variation as a function of Big 5 dimensions of human personality
GEO Series GSE60491. Homo sapiens. 119 samples. Type: Expression profiling by array.
Chromatin and gene expression profile at single nuclei level of CD45+ leukocytes from the rhesus brain parenchyma
GEO Series GSE261968. Macaca mulatta. 8 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Leukocyte gene expression variation as a function of chronic caregiving stress
GEO Series GSE52319. Homo sapiens. 261 samples. Type: Expression profiling by array.
In vitro exposure of leukocytes to HIV pre-exposure prophylaxis (PrEP) decreases mitochondrial function and alters gene expression profiles.
GEO Series GSE159339. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Leukocyte gene expression as a function of perceived social isolation (PSI): Year 10
GEO Series GSE65403. Homo sapiens. 100 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.