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120
datasets available to search
ShareScore release 0.9.0
Dataset results
120 results for “long-read sequencing”
High-throughput manual-quality annotation of full-length long noncoding RNAs with Capture Long-Read Sequencing (CLS)
GEO Series GSE93848. Mus musculus; Homo sapiens. 36 samples. Type: Non-coding RNA profiling by high throughput sequencing.
An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing
<p>Relavant codes and notebooks for data analysis: <a href="https://github.com/lzx325/CRC-atlas">https://github.com/lzx325/CRC-atlas</a></p>
Accurate isoform quantification by joint short- and long-read RNA-sequencing
GEO Series GSE271530. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Long-read sequencing for the assessment of therapeutic CRISPR/Cas9 strategy for the removal of aberrant DM1-causing CTG repeats in DMPK gene locus
GEO Series GSE279054. Homo sapiens. 5 samples. Type: Other.
Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station
Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground control, after direct exposure to space conditions onboard the International Space Station (ISS) for 1.5 years. The resulting ISS-flown and non-flown strains were sequenced using the Nanopore MinION and an in-house method and pipeline to identify methylated positions in the genome. Our analysis indicated genomic variants and m6A methylation increased in the ISS-flown SAFR-032. To complement the broader omics investigation and explore phenotypic changes, ISS-flown and non-flown strains were compared in a series of laboratory-based chamber experiments using an X-ray irradiation source (doses applied at 250, 500, 750, 1000 and 1250 Gy); results show a potentially higher survival fraction of ISS-flown DS2 at the two highest exposures. Taken together, results from this study document lasting changes to the genome by methylation, potentially triggered by conditions in spaceflight, with functional consequences for the resistance of bacteria to stressors expected on long-duration missions beyond low Earth orbit.
Long-read RNA sequencing reveals synaptic genes with differential isoform usage in schizophrenia [long-read RNAseq ]
GEO Series GSE282551. Homo sapiens. 30 samples. Type: Expression profiling by high throughput sequencing.
Long-read RNA sequencing reveals synaptic genes with differential isoform usage in schizophrenia [short-read RNAseq ]
GEO Series GSE282552. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Long-Read Single-Cell Sequencing Confirms the Synaptic Disruptions and Developmental Delays in Neurabin I+/- iNeurons: Molecular Rescue via Gene-based Approaches
GEO Series GSE283629. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Long-Read Sequencing and Proteomics Reveal Blood Transcriptome and Protein Expression Profiles in Multiple Primary Lung Cancers
GEO Series GSE311391. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Long-read single-cell RNA sequencing analysis of key genes and isoforms during corneal wound healing in Macaca fascicularis
GEO Series GSE278797. Macaca fascicularis. 6 samples. Type: Expression profiling by high throughput sequencing.
Long-read RNA Sequencing of Human Meningiomas
GEO Series GSE300855. Homo sapiens. 84 samples. Type: Expression profiling by high throughput sequencing.
Long-read nascent RNA sequencing from S. pombe
GEO Series GSE104679. Schizosaccharomyces pombe. 4 samples. Type: Expression profiling by high throughput sequencing; Other.
Comparative multi-omic analyses of Trichinella Pseudospiralis based on a new genome assembly by long-read sequencing
GEO Series GSE113105. Trichinella pseudospiralis. 6 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Benchmarking long-read RNA-sequencing technologies with LongBench: a cross-platform reference dataset profiling cancer cell lines with bulk and single-cell approaches
GEO Series GSE303762. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic plasticity is a driver of heritable pollution tolerance in Atlantic killifish [ONT Long-read sequencing; DNA]
GEO Series GSE313974. Fundulus heteroclitus. 4 samples. Type: Other.
Targeted Long-Read Sequencing of the Ewing Sarcoma 6p25.1 Susceptibility Locus
Ewing Sarcoma (EwS) is rare but the second most common cancer in children, adolescents and young adults. Recent studies suggest germline variation in or around GGAA microsatellites may interact with fusion oncoprotein binding causing changes in binding affinity and potentially impacting enhancer activity on nearby target genes. This study aims to better understand germline variation around EwS susceptibility regions by performing long-range haplotype sequencing of these regions using PacBio sequencing. Our analysis focused on characterizing variation in GGAA microsatellite length as well as germline variants in or around the microsatellite and their association with EwS risk.
LINE-1 transposable elements regulate the exit of human pluripotency and early brain development [long-read RNA and DNA sequencing]
GEO Series GSE283599. Homo sapiens. 4 samples. Type: Other.
Pacbio long read Iso-sequencing is performed to acquire a high-precision transcription landscape after STAMBPL1 knockingdown in Huh7 cells（Long-read）
GEO Series GSE276508. Homo sapiens. 4 samples. Type: Other.
Long-read sequencing for molecular diagnostics in constitutional disorders
<p>These are the alignment files (.bam) for specific gene regions (TRIOBP for Patient 1 and STRC for Patient 2) from PacBio long-read sequencing. These patients were referred to genetic testing for hearing loss and received an inconclusive result from the standard of care testing. Long-read sequencing was performed to infer phase without parental samples and resolve the diagnostic dilemma. This is part of the publication submitted to Human Mutation (Conlin LK et al., Long-read sequencing for molecular diagnostics in constitutional genetic disorders, Human Mutation, Submitted).</p>
Long-reads Next Generation Sequencing for the analysis of mitochondrial DNA
<p>Long-reads Next Generation Sequencing for the analysis of mitochondrial DNA</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.