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2,182 results for “organoid”
Depletion of hypercapnia-responsive neurons in human cerebral- and brainstem-organoids of congenital central hypoventilation syndrome
<p>key Rdata for the paper.</p>
Tabular datasets for for Morrone Parfitt, G., Coccia, E., Goldman, C. et al. Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model. Nat Commun 15, 447 (2024). https://doi.org/10.1038/s41467-024-44732-2
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Transcriptional atlas of kidney organoid development
<p>This repository contains curated AnnData objects for the kidney organoid atlas published in Wilson et al., 2024 (1) and further analysed in Wilson et al., 2024 (2). These objects can be opened in a cellxgene instance for instant visualisation and investigation.</p> <p>Wilson_kidney_organoid_atlas.h5ad; The entire dataset, all cells at all time points</p> <p>Wilson_KidneyOrganoid_Stage1_atlas.h5ad; The cells in Stage1, containing iPSC, day 3, day 4 and day 5 time-points</p> <p>Wilson_KidneyOrganoid_Stage2_atlas.h5ad; The cells in Stage2, all day 7, day 8 and day 9 time-points</p> <p>Wilson_KidneyOrganoid_Stage3_atlas.h5ad; The cells in Stage3, all day 12, day 13 and day 14 time-points</p> <p>Wilson_KidneyOrganoid_Stage4_atlas.h5ad; The cells in Stage4, all day 27 time-points, the final collection point and the most mature organoids.</p> <p> </p>
Dataset related to article "Neonicotinoid pesticides affect developing neurons in experi-mental mouse models and in human induced pluripotent stem cell (iPSC)-derived neural cultures and organoids"
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Neonicotinoid pesticides affect developing neurons in experi-mental mouse models and in human induced pluripotent stem cell (iPSC)-derived neural cultures and organoids
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Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinoma
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Imaging dataset for positron emission microscopy of patient-derived tumor organoids
<p>Here, we present a microscopy method to image <sup>18</sup>F-fluorodeoxyglucose and other radiotracers in patient-derived tumor organoids with spatial resolution up to 100-fold better than that of clinical positron emission tomography (PET). When combined with brightfield imaging, this metabolic imaging approach functionally mirrors clinical PET/CT scans and provides a quantitative readout of cell glycolysis other metabolic processes. </p>
The Clinical Efficacy of Drug Sensitive Neoadjuvant Chemotherapy Based on Organoid Versus Traditional Neoadjuvant Chemotherapy in Advanced Rectal Cancer
ClinicalTrials.gov study NCT05352165. IPD Sharing: NO. Countries: 0. Publications: 7.
Patient-Derived Organoids for Rectal Cancer
ClinicalTrials.gov study NCT04371198. IPD Sharing: YES. Countries: 1. Publications: 0.
Gut Organoid and Microbiome Interactions in Hypertension
ClinicalTrials.gov study NCT04497727. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Establishment and Validation of Prediction Model of Simultaneous Chemoradiotherapy for Cervical Cancer Organoids
ClinicalTrials.gov study NCT06786780. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Treatment of Refractory Breast Cancer Based on Organoid Drug Sensitivity Results
ClinicalTrials.gov study NCT06438055. IPD Sharing: NO. Countries: 0. Publications: 19.
Organoid-driven Chemotherapy Choice in Metastatic Pancreatic Cancer Patients.
ClinicalTrials.gov study NCT06615830. IPD Sharing: NO. Countries: 0. Publications: 13.
Imaging dataset for positron emission microscopy of patient-derived tumor organoids
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Vitamin D receptor (VDR) ChIP-Seq on human colonic organoids stimulated with 1,25(OH)2D3
GEO Series GSE206176. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
GEO Series GSE124299. Pan troglodytes; Macaca mulatta; Homo sapiens. 3096 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
Single-cell transcriptional analysis of human pluripotent stem cell-derived heart epicardium-myocardium organoids uncover principals of human epicardial-derived cells specification and coronary vascul
GEO Series GSE309829. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis
GEO Series GSE148366. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Single cell profiling of the cerebral organoids derived from Schinzel-Giedion syndrome cells and isogenic controls
GEO Series GSE171263. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
In vivo intratumoral Heterogeneity in a dish: Scalable Forebrain Organoid Models of Embryonal Brain Tumors for High-Throughput Personalized Drug Discovery (human organoids+cell lines subset 1)
GEO Series GSE269254. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.