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Chromatin Accessibility Plays a Key Role in Selective Targeting of Hox Proteins
<p>Supplementary data tables for bioRxiv preprint "Chromatin Accessibility Plays a Key Role in Selective Targeting of Hox Proteins "</p> <p>All tables as Tab Delimited Text files</p>
Benchmark results for Vellamo and AnTuTu from Google Play in Xiaomi Redmi Note 4
<p>The dataset contains the print screens of the execution of following benchmark: Vellamo Browser, Vellamo Metal, Vellamo Multicore, and AnTuTu General. The benchmark was repeated until the smartphone reaches a battery level below 20%. For each benchmark, we recorded the numerical results for each microbenchmark. Each benchmark was evaluated using different approaches for CPU frequency scaling: Ondemand, Performance, Interactive, HS, ZT, OUR-G-0.1, OUR-G-0.5 and OUR-G-0.9.</p> <p>Ondemand, Performance, and Interactive are native from Android OS.</p> <p>OUR-G-0.1, OUR-G-0.5 and OUR-G-0.9 referrers to our proposed method to save energy, executed in smartphone Xiaomi Redmi Note 4.</p> <p>The approaches HS is from:<br> @article{hshen2013,<br> author = "H. Shen and Y. Tan and J. Lu and Q. Wu and Q. Qiu",<br> title = "Achieving Autonomous Power Management Using Reinforcement Learning",<br> journal = "ACM Transactions on Design Automation of Electronic Systems (TODAES)",<br> volume = "18",<br> month = "",<br> number = "2",<br> year = "2013",<br> pages = "24-32"<br> }</p> <p>and ZT in from:<br> @inproceedings{ztian2018,<br> author = "Zhongyuan Tian and Zhe Wang and Haoran Li and Peng Yang and Rafael Kioji Vivas Maeda and Jiang Xu",<br> title = "Multi-device collaborative management through knowledge sharing",<br> booktitle = "Proc. 23rd Asia and South Pacific Design Automation Conference (ASP-DAC)",<br> month = "" ,<br> year = "2018",<br> pages = "22-27"<br> }</p> <p>The energy.txt file contains the acquisition of voltage and current from smartphone fuel gauge.</p> <p>The other files are self-explained.</p> <p> </p> <p> </p>
Performance simulation of short term alternative refrigerants for plug and play small size reversible heat pump
<p>This dataset is generated by CNR-ITC in order to simulate and compare the thermodynamic performance of short-term alternative refrigerants in HP cycles at various operating conditions. The purpose of this dataset within the project is to select the most promising fluid to be used in the plug and play small size reversible HP prototype developed by HIREF.<br> The generated data are thermodynamic properties and performance (COP, VRE) values from simulation of thermodynamic HP cycles with homemade software developed in Matlab environment.</p>
Together by Debbie Wiseman - Preethi Premkumar playing
<p>Preethi Premkumar recorded her playing of Debbie Wiseman's "Together" on the piano in April 2024 during the COVID pandemic.</p>
PLayer: A Plug-and-Play Embedded Neural System to Boost Neural Organoid 3D Reconstruction
<p>This dataset supports the study titled "PLayer: A Plug-and-Play Embedded Neural System to Boost Neural Organoid 3D Reconstruction." It comprises a total of 539 high-resolution images, each with dimensions of 2048x2048 pixels. The image collection took place roughly over one month. We cultured the neural organoids ourselves based on the STEMdiff™ Cerebral Organoid Kit (STEMCELL Technologies Catalog #08570), aged 19, 34, 71, and 112 days, and the STEMdiff™ Dorsal Forebrain Organoid Differentiation Kit (STEMCELL Technologies Catalog #08620), aged 82 days. All organoids were collected on the same day, rinsed twice with PBS to remove any residual medium, and subsequently fixed with 4.0% (w/v) PFA at 4°C overnight before processing.</p>
Mr Burns: a post-electric play written by Anne Washburn / A tertiary performance staged by Te Kura o Toi Whakaari: NZ Drama School
<p>DIRECTOR</p> <p>Stella Reid</p> <p>MUSICAL DIRECTOR</p> <p>Hayden Taylor</p> <p>PRODUCER</p> <p>Natasha James</p> <p>CHOREOGRAPHER</p> <p>Stella Reid</p> <p>FIGHT CHOREOGRAPHY</p> <p>Shane Rangi</p> <p>LIGHTING DESIGNER</p> <p>Grace Newton</p> <p>SOUND DESIGNER</p> <p>Oliver Devlin</p> <p>DIALECT COACH</p> <p>Jacque Drew</p> <p>SET DESIGNER</p> <p>Eden Winters</p> <p>COSTUME DESIGNER</p> <p>Tessa Saunders</p> <p>ASSISTANT SOUND DESIGNER</p> <p>Jade Alborn</p> <div> <p>PRODUCTION TEAM</p> <p>PRODUCTION MANAGER</p> <p>Olivia Cowley</p> <p>STAGE MANAGER</p> <p>Michael Lyell-O'Reilly</p> <p>HEAD MECHANIST</p> <p>Caleb Grainger</p> <p>PUTY STAGE MANAGER/SHOW CALLER</p> <p>Sarah Davitt</p> <p>DEPUTY STAGE MANAGER</p> <p>Joseph McAllum</p> <p>PRODUCTION ASSISTANT</p> <p>Isla McLarin</p> <p>MECHANIST</p> <p>Eilidh Hamilton</p> <p>MECHANIST</p> <p>Jack Tankersley</p> <p>SOUND OPERATOR/ENGINEER</p> <p>Paige Johns</p> <p>LIGHTING OPERATOR</p> <p>Luci McDougall</p> <p>COSTUME SUPERVISORS</p> <p>Sally Huges-Allen, Maysie Pyatt, Evan Stone, Kaitlyn Jacobs</p> <p> </p> <p>PRODUCTION TEAM</p> <p>COSTUME CONSTRUCTION</p> <p>Maxence Benoist, Lillian Denness,</p> <p>Renske Gordon, Evie Howard, Maria McCarthy, Dottie Olsen, Mikkel Rivett,</p> <p>Hannah van den Eikhof, Jordyn Williams</p> <p>SET CONSTRUCTION & SCENIC PAINTING</p> <p>Emile Commarieu, Molly Friis, Azalea Lewis-Milne, Lora Nankivell, Grace O'Brien, Weston Symes</p> <p> </p> <p> </p> <p>CAST</p> <p>ZACHARY BELL - МАТТ/ACT II, HOMER/ACT III CHORUS</p> <p>BRAYDEN CRESWELL- GIBSON/SIDESHOW BOB, FIRST FBI AGENT / TROY MCCLURE</p> <p>FIPE FOAI - ACT III BART</p> <p>EMILIO FUENTES MANCILLA - ACT III LISA/APU</p> <p>KIMIORA HONEYCOMBE - JENNY ACT II, MARGE/ACT III CHORUS</p> <p>JUSTICE KALOLO - SAM ACT II, BART/ACT III, CHORUS /ACT III SCRATCHY</p> <p>SARAH LAWRENCE - COLLEEN, ACT III CHORUS</p> <p>MAIZY METEKINGI - ACT III MARGE/FLANDERS</p> <p>IZZIE NEWTON-CROSS - ITCHY/NELSON</p> <p>SUGAR REA-BRUCE MARIA/ACT II, LISA/2ND FBI AGENT/EDNA KRABAPPEL</p> <p>TAMAHOU TEHEI - ACT III HOMER / WILLY</p> <p>PARIS TUIMASEVE-FOX - QUINCY/ACT II, MAGGIE/ACT III CHORUS</p> <p>CASSIDY KEMP-WOFFENDEN - MR BURNS</p> <p>IAN BLACKBURN - MR BURNS SWING</p> </div>
Barley endosomal MONENSIN SENSITIVITY1 is a target of the powdery mildew effector CSEP0162 and plays a role in plant immunity
<p><span>Encasements formed around haustoria and biotrophic hyphae as well as hypersensitive reaction (HR) cell death are essential plant immune responses to filamentous pathogens. In this study we examine the components that may contribute to the absence of these responses in susceptible barley attacked by the powdery mildew fungus. We find that the effector CSEP0162 from this pathogen targets plant MONENSIN SENSITIVITY1 (MON1), which is important for the fusion of multivesicular bodies to their target membranes. Overexpression of CSEP0162 and silencing of barley MON1 both inhibit encasement formation. We find that the Arabidopsis ecotype No-0 has resistance to powdery mildew, and that this is partially dependent on MON1. Surprisingly, we find the MON1-dependent resistance in No-0 not only includes an encasement response, but also an effective HR. Similarly, silencing of MON1 in barley also blocks Mla3-mediated HR-based powdery mildew resistance. Our results indicate that MON1 is a vital plant immunity component, and we speculate that the barley powdery mildew fungus introduces the effector CSEP0162 to target MON1 and hence reduces encasement formation and HR.</span></p>
Data for: Repeated genetic divergence plays a minor role in repeated phenotypic divergence of lake-stream stickleback
<p>Recent studies have shown that the repeated evolution of similar phenotypes in response to similar ecological conditions (here 'parallel evolution') often occurs through mutations in the same genes. However, many previous studies have focused on known candidate genes in a limited number of systems. Thus, the question of how often parallel phenotypic evolution is due to parallel genetic changes remains open. Here, we used quantitative trait locus (QTL) mapping in F2 intercrosses between lake and stream threespine stickleback (<em>Gasterosteus aculeatus</em>) from four independent watersheds on Vancouver Island, Canada to determine whether the same QTL underlie divergence in the same phenotypes across, between, and within watersheds. We find few parallel QTL, even in independent crosses from the same watershed or for phenotypes that have diverged in parallel. These findings suggest that different mutations can lead to similar phenotypes. The low genetic repeatability observed in these lake-stream systems contrasts with the higher genetic repeatability observed in other stickleback systems. We speculate that differences in evolutionary history, gene flow, and/or the strength and direction of selection might explain these differences in genetic parallelism and emphasize that more work is needed to move beyond documenting genetic parallelism to identifying the underlying causes.</p>
When parents play favourites: Brood demand shapes parental preference for offspring UV colour
<p><span>Parents might initially produce more offspring than they might be able to raise. However, when offspring demand exceeds their parents´ rearing capacity, parents might shift care towards the offspring that yield greater fitness returns to </span><span>achieve their optimal brood size via brood reduction</span><span>. Such favoritism could rely on offspring signaling traits if these inform parents about offspring quality and hence about the pay-offs of their investment. Here we investigated whether favoritism of blue tit (<em>Cyanistes caeruleus</em>) parents for an offspring signal (i.e., ultraviolet (UV) plumage coloration) varies with brood demand. To test this, we experimentally blocked the UV reflectance of yellow breast feathers in half of the nestlings of each brood, and then we sequentially performed two opposing brood size manipulations </span><span>to vary nestling demand below or above parental rearing capacity</span><span>. In reduced broods, nestlings begged overall less intensely and gained more body mass, supporting that parental rearing capacities sufficed to satisfy brood demand. Moreover, in reduced broods, UV-blocked nestlings (i.e., low-quality offspring) were fed and prey-tested more often. Yet, they begged more than control nestlings, suggesting that they were perhaps treated differently by other family members or that they may exploit parental preferences beyond actual need (at least in reduced nests). Parents flexibly shifted their feeding rate and favoritism in response to short-term changes in family size, as there was no parental preference in enlarged broods. Such flexible parental feeding rules may allow parents to gain the upper hand in parent-offspring conflict. However, we did not find evidence that parental favoritism facilitated brood reduction, at least in conditions were demand was temporally enhanced.</span> </p>
Inflammatory responses induced by the monophasic variant of Salmonella typhimurium in pigs play a role in the high shedder phenotype and fecal microbiota composition
<p>Pigs infected with <em><span>Salmonella</span></em> may excrete large amounts of <em><span>Salmonella</span></em>, increasing the risk of spread of this pathogen in the food chain. Identifying <em><span>Salmonella</span></em> high shedder pigs is therefore required to mitigate this risk. We analyzed immune-associated markers and composition of the gut microbiota in specific-pathogen-free pigs presenting different shedding levels after an oral infection with <span>Salmonella</span>. Immune response was studied through total blood cell counts, production of anti-<em><span>Salmonella</span></em> antibodies and cytokines, and gene expression quantification. Total <em><span>Salmonella</span></em> shedding for each pig was estimated and hierarchical clustering was used to cluster pigs into high, intermediate, and low shedders. Gut microbiota compositions were assessed using 16S rRNA microbial community profiling. Comparisons were made between control and inoculated pigs, then between high and low shedders pigs. Prior to infection, high shedders had similar immunological profiles compared to low shedders. As soon as 1 day postinoculation (dpi), significant differences in the cytokine production level and on the expression level of several host genes related to a proinflammatory response were observed between high and low shedders. Infection with <em><span>Salmonella</span></em> induced an early and profound remodeling of the immune response in all pigs, but the intensity of the response was stronger in high shedders. In contrast, low shedders seroconverted earlier than high shedders. Just after induction of the proinflammatory response (at 2 dpi), some taxa of the fecal microbiota were specific to the shedding phenotypes. This was related to the enrichment of several functional pathways related to anaerobic respiration in high shedders. In conclusion, our data show that the immune response to <em><span>Salmonella</span></em> modifies the fecal microbiota and subsequently could be responsible for shedding phenotypes. Influencing the gut microbiota and reducing intestinal inflammation could be a strategy for preventing <em><span>Salmonella</span></em> high shedding in livestock.</p>
Breastfeeding, carrying, grooming, and playing behaviours in wild Javan gibbons (Hylobates moloch)
<p><span>In pair-living species, female and male pairs may maintain stable social bonds by adjusting spatial and social associations. Nevertheless, each sex invests differently to maintain the pair bond, and the investment can depend on the presence of paternal care or 'male services.' While most species live in pairs, the sex responsible for pair bond maintenance in gibbons is still controversial. We investigated pair bond maintenance and parental care in three pairs of wild Javan gibbons in Gunung Halimun-Salak National Park, Indonesia, for over 21 months. We found that Javan gibbon fathers groomed their offspring more than adult females, especially as offspring get older. While both parents increased playing time with offspring when offspring became older and more independent, fathers played with offspring 20 times more than mothers on average. Grooming within Javan gibbon pairs was male-biased, suggesting that pair bond maintenance was heavily the job of males. However, offspring age as a proxy for paternal care did not affect the pair bond maintenance. Our study highlights that adult male Javan gibbons may have an important role in pair bond maintenance and the care of juveniles.</span></p>
The significance of parental mentalizing for four-year-old children's solitary pretend play
<p>De-identified data set necessary to replicate the findings reported in our study "The significance of parental mentalizing for four-year-old children’s solitary pretend play".</p> <p><strong>Abstract</strong></p> <p><strong>Background.</strong> Pretend play is a signature behavior of early childhood and is considered to reflect the child’s emerging symbolic function, enabling the interpretation of social signals, language development, and emotion understanding. While theory links parental mentalizing with children’s pretend play, only a few studies have investigated this association. These studies are limited to infancy and toddlerhood, and child pretend play is assessed during play with an adult (social play). Based on the assumption that child solitary pretend play reflects the child’s ‘baseline’ pretend play ability, in this study, we investigate children’s pretend play at its peak, i.e., during the preschool age without the facilitation of another player. The overall objective was to investigate if parental mentalizing increases pretend play complexity in children.</p> <p><strong>Methods.</strong> The sample consisted 99 Danish mothers and their 4-year-old children. Employing a cross-sectional design, we hypothesized that parental mentalizing during interaction with the child ('online' mentalizing) is a mechanism through which parental reflective functioning ('offline' mentalizing) is associated with child solitary pretend play. Child pretend play complexity was observed and coded with an adapted version of the 12-Step Play Scale. Maternal offline mentalizing was assessed with the Parental Reflective Functioning Questionnaire, and maternal online mentalizing was assessed by coding the mothers’ use of mental state language during interaction with the child using the Mind-mindedness approach.</p> <p><strong>Results.</strong> While there was no direct effect of maternal offline mentalizing on child pretend play, online mentalizing mediated the link between offline mentalizing and child pretend play.</p> <p><strong>Conclusions.</strong> These results provide support for the theoretically assumed link between parental mentalizing and children’s capacity for pretend play. Furthermore, our study contributes to the literature on parental mentalization, suggesting that parental mentalizing facilitates child development only if the parent can translate this ability into 'mentalizing in action'.</p>
Risky Play: A Risk-based Case Study for Common Mode Current Assessment of a Medical Plasma Device (Dataset)
<p>This dataset contains raw- and de-embedding data which are the source of the referenced publication's plots.</p> <p>Uploaded are raw common mode current measurements in dBm as a .mat file, touchstone files for the cable used and characteristics of the Fischer Customs Communication F-75 and F-2000 probes as .csv, both used for de-embedding cable and current probe from the raw data. </p> <p>In addition, touchstone files of the input impedance measurements are contained.</p> <p>This research is part of a project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 955816 (MSCA-ETN ETERNITY)</p>
"Effect of LEGO® Serious Play® Trauma-Informed Care Training on Nursing Students
ClinicalTrials.gov study NCT07304609. IPD Sharing: NO. Countries: 1. Publications: 18.
Efficacy of the START-Play Program for Infants With Neuromotor Disorders
ClinicalTrials.gov study NCT02593825. IPD Sharing: NO. Countries: 1. Publications: 6.
Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention
ClinicalTrials.gov study NCT02153736. IPD Sharing: NO. Countries: 1. Publications: 1.
Supporting Together Exercise and Play and Improving Nutrition
ClinicalTrials.gov study NCT02724839. IPD Sharing: NO. Countries: 1. Publications: 1.
Play Intervention for Dementia for Promoting Cognitive Function: A Feasibility Study
ClinicalTrials.gov study NCT02846415. IPD Sharing: NO. Countries: 1. Publications: 5.
Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome
ClinicalTrials.gov study NCT05307523. IPD Sharing: NO. Countries: 1. Publications: 12.
The Effect of Play on Social and Motor Skills of Children With ASD
ClinicalTrials.gov study NCT04258254. IPD Sharing: NO. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.