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454
datasets available to search
ShareScore release 0.9.0
Dataset results
454 results for “preclinical”
Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV- 2 mRNA vaccination
GEO Series GSE254537. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Highly selective HSP90 inhibitor, pimitespib, demonstrates its potent growth suppressive activity to adult T-cell leukemia in preclinical models (Su9T01).
GEO Series GSE168558. Homo sapiens. 6 samples. Type: Expression profiling by array.
Zongertinib (BI01810631), an irreversible HER2 TKI, spares EGFR signaling and improves therapeutic response in preclinical models and patients with HER2-driven cancers
GEO Series GSE252799. Homo sapiens. 90 samples. Type: Expression profiling by high throughput sequencing.
Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease
GEO Series GSE249611. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [Click-Seq 1]
GEO Series GSE88748. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Insights into the mechanisms of serplulimab: a distinctive anti-PD-1 monoclonal antibody, in combination with a TIGIT or LAG3 inhibitor in preclinical tumor immunotherapy studies
GEO Series GSE263274. Mus musculus. 45 samples. Type: Expression profiling by high throughput sequencing.
Antitumor Activity of the Novel Flavonoid Oncamex in Preclinical Breast Cancer Models
GEO Series GSE70949. Homo sapiens. 10 samples. Type: Expression profiling by array.
Rational selection of syngeneic preclinical tumor models for immunotherapeutic drug discovery
GEO Series GSE85509. Mus musculus. 299 samples. Type: Expression profiling by array; Genome variation profiling by genome tiling array.
Intratumoral administration of lipid nanoparticles carrying mRNA encoding for IL-21, IL-7, and 4-1BBL induces anti-tumor immunity in preclinical tumor models.
GEO Series GSE249674. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Glycaemic variability identified as a critical determinant of myocyte dysfunction and risk for myocardial injury in preclinical models of diabetes
GEO Series GSE279917. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Analysis of the brain metastasis-associated microenvironment in different preclinical models of brain metastasis
GEO Series GSE231646. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy II
GEO Series GSE145349. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
A novel preclinical mouse model of spontaneous breast cancer metastasis
GEO Series GSE34666. Mus musculus. 35 samples. Type: Genome variation profiling by genome tiling array.
Preclinical Validation of a Microarray Method for Full Molecular Karyotyping of Blastomeres in a 24-hour Protocol
GEO Series GSE19247. Homo sapiens. 622 samples. Type: Other.
Targeting SUMOylation triggers interferon-beta-dependent activation of patient and allogenic Natural Killer cells in preclinical models of Acute Myeloid Leukemia [CUT&RUN]
GEO Series GSE285061. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution.
GEO Series GSE173339. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [Click-Seq 2]
GEO Series GSE88749. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MRTX1719 is an MTA-cooperative PRMT5 inhibitor that exhibits synthetic lethality in preclinical models and patients with MTAP deleted cancer
GEO Series GSE240145. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Preclinical evaluation of the efficacy of anti-human SIRPα antibody for cancer immunotherapy using the MITRG humanized mouse model
GEO Series GSE239693. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Ex Vivo Lung Perfusion as a Human Platform for Preclinical Small Molecule Testing
GEO Series GSE118566. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.