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140 results for “secondary metabolites”
Data from: Secondary metabolites in floral nectar reduce parasite infections in bumblebees
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Data from: Light and nutrient dependent responses in secondary metabolites of Plantago lanceolata offspring are due to phenotypic plasticity in experimental grasslands
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Data from: A plant pathogen modulates the effects of secondary metabolites on the performance and immune function of an insect herbivore
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The COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus [ATAC-seq]
GEO Series GSE285953. Aspergillus flavus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Comparative transcriptome analysis of a novel obligate Methylomonas sp. DH-1 reveals key differences in the transcriptional responses in C1 and secondary metabolite pathways during growth on methane a
GEO Series GSE101494. Methylomonas sp. DH-1. 6 samples. Type: Expression profiling by high throughput sequencing.
Ribosome pausing at the AT-rich codons regulates the protein expression of secondary metabolite gene clusters in the Streptomyces tsukubaensis NRRL 18488
GEO Series GSE97637. Streptomyces tsukubensis. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
Knock-down of the methyltransferase Kmt6 reliefs H3K27me3 and induces expression of cryptic otherwise silent secondary metabolite gene clusters in Fusarium fujikuroi [gene expression]
GEO Series GSE80477. Fusarium fujikuroi. 12 samples. Type: Expression profiling by array.
Analysis the Ability of Producing Secondary Metabolites of Streptomyces bingchenggensis By The Genome Sequence and GeneChip DNA microarrays
GEO Series GSE32205. Streptomyces bingchenggensis BCW-1; Streptomyces bingchenggensis. 16 samples. Type: Expression profiling by array.
Metabolic regulation of filamentous fungi is tailored for secondary secondary metabolite production
GEO Series GSE106983. Penicillium coprophilum; Penicillium decumbens; Penicillium flavigenum; Penicillium polonicum; Penicillium nalgiovense; Penicillium steckii. 36 samples. Type: Expression profiling by high throughput sequencing.
The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters
GEO Series GSE50689. Fusarium graminearum. 36 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Deletion of the celA gene in Aspergillus nidulans triggers overexpression of secondary metabolite biosynthetic genes
GEO Series GSE94110. Aspergillus nidulans. 6 samples. Type: Expression profiling by high throughput sequencing.
Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence
GEO Series GSE97495. Aspergillus fumigatus. 18 samples. Type: Expression profiling by high throughput sequencing.
Secondary metabolites in leaves of hybrid aspen (Populus tremula L. × P. tremuloides Michx.)
<p>This data set was generated as part of the study "Secondary metabolites in leaves of hybrid aspen are affected by the competitive status and early thinning in dense coppices", published in Annals of Forest Science in 2020.</p>
Data from: Convergently evolved toxic secondary metabolites in plants drive the parallel molecular evolution of insect resistance
Natural selection imposed by natural toxins has led to striking levels of convergent evolution at the molecular level. Cardiac glycosides represent a group of plant toxins that block the Na,K-ATPase, a vital membrane protein in animals. Several herbivorous insects have convergently evolved resistant Na,K-ATPases, and in some species, convergent gene duplications have also arisen, likely to cope with pleiotropic costs of resistance. To understand the genetic basis and predictability of these adaptations, we studied five independent lineages of leaf-mining flies (Diptera: Agromyzidae). These flies have colonized host plants in four botanical families that convergently evolved cardiac glycosides of two structural types: cardenolides and bufadienolides. We compared each of six fly species feeding on such plants to a phylogenetically related but nonadapted species. Irrespective of the type of cardiac glycoside in the host plant, five out of six exposed species displayed substitutions in the cardiac glycoside–binding site of the Na,K-ATPase that were previously described in other insect orders; in only one species was the gene duplicated. In vitro assays of nervous tissue extractions confirmed that the substitutions lead to increased resistance of the Na,K-ATPase. Our results demonstrate that target site insensitivity of Na,K-ATPase is a common response to dietary cardiac glycosides leading to highly predictable amino acid changes; nonetheless, convergent evolution of gene duplication for this multifunctional enzyme appears more constrained.
Figure 4 from: Rupcic Z, Chepkirui C, Hernández-Restrepo M, Crous PW, Luangsa-ard JJ, Stadler M (2018) New nematicidal and antimicrobial secondary metabolites from a new species in the new genus, Pseudobambusicola thailandica. MycoKeys 33: 1-23. https://doi.org/10.3897/mycokeys.33.23341
Figure 4 COSY, HMBC and ROESY correlations of 1.
Figure 3 from: Rupcic Z, Chepkirui C, Hernández-Restrepo M, Crous PW, Luangsa-ard JJ, Stadler M (2018) New nematicidal and antimicrobial secondary metabolites from a new species in the new genus, Pseudobambusicola thailandica. MycoKeys 33: 1-23. https://doi.org/10.3897/mycokeys.33.23341
Figure 3 Chemical structures of thailanones A–F (1–6), monocerin (7) and deoxyphomalone (8).
FIG. 2 in Analysis of lichen secondary metabolites and morphometrics in the Cladonia chlorophaea species group (Cladoniaceae, lichenized Ascomycota) in Hungary
FIG. 2. — Distribution of Cladonia chlorophaea s.l. species in Hungary before revision.
ctDNA and Metabolites in CSF as Early Biomarkers of Secondary CNS Involvement in Diffuse Large B-cell Lymphoma
ClinicalTrials.gov study NCT04112238. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Convergently evolved toxic secondary metabolites in plants drive the parallel molecular evolution of insect resistance
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Plant recognition by Trichoderma harzianum elicits upregulation of a novel secondary metabolite cluster required for colonization
GEO Series GSE229209. Trichoderma harzianum. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.