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115
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ShareScore release 0.9.0
Dataset results
115 results for “time-dependence”
Genome-wide analysis of time-dependent gene expression in MCF-10A cells treated with the EGFR-specific inhibitor gefitinib for 45 hours
GEO Series GSE23135. Homo sapiens. 16 samples. Type: Expression profiling by array.
Time-Dependent miRNA Profiling Following Ischemia/Reperfusion Injury in Rat Retina
GEO Series GSE61072. Rattus norvegicus. 60 samples. Type: Non-coding RNA profiling by array.
Identification of time-dependent biomarkers and effects of exposure to volatile organic compounds using high-throughput analysis
GEO Series GSE68909. Homo sapiens. 72 samples. Type: Expression profiling by array; Methylation profiling by genome tiling array.
Time-dependent toxic effects of dietary TCDD in juvenile rainbow trout
GEO Series GSE45780. Coregonus clupeaformis; Oncorhynchus mykiss; Salmo salar; Oncorhynchus tshawytscha; Osmerus mordax. 16 samples. Type: Expression profiling by array.
Genome-wide analysis of time-dependent gene expression in MCF-10HER-2 cells treated with the EGFR-specific inhibitor gefitinib for 45 hours
GEO Series GSE23136. Homo sapiens. 16 samples. Type: Expression profiling by array.
Time-dependent transcriptomic profiles of mouse hippocampus in kainic acid-induced mesial temporal lobe epilepsy (MTLE)
GEO Series GSE73878. Mus musculus. 80 samples. Type: Expression profiling by array.
Time-dependent molecular responses differ between gastric bypass and dieting but are conserved across species
GEO Series GSE113823. Homo sapiens; Mus musculus. 58 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing.
SARS-CoV-2 airway infection results in time-dependent sensory abnormalities in a hamster model
GEO Series GSE224710. Mesocricetus auratus. 30 samples. Type: Expression profiling by high throughput sequencing.
Hepatic BMAL1 and HIF1a regulate a time-dependent hypoxic response and their absence leads to Hepatopulmonary Syndrome
GEO Series GSE254219. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Time-dependent expression data from human fibrosarcoma human cell line (HT1080) in collagen matrix with protease inhibitors
GEO Series GSE197310. Homo sapiens. 9 samples. Type: Expression profiling by array.
Time-dependent changes in gene expression after endotoxinic challenge followed by LR12-scrambled or LR12 treatment.
GEO Series GSE48311. Macaca fascicularis; Homo sapiens. 56 samples. Type: Expression profiling by array.
A Time-dependent Glia cell-Mediated Neuroprotective Effects of Kv7/KCNQ channel opener QO-83 in Ischemic Stroke: Mechanisms of Action and Therapeutic Potential
GEO Series GSE244576. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
Selective time-dependent changes in activity- and cell-specific gene expression in human postmortem brain
GEO Series GSE153669. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article: "Time-dependent effect of GLP-1 receptor agonists on cardiovascular benefits: a real-world study"
<p>This record contains data related to article "<strong>Time-dependent effect of GLP-1 receptor agonists on cardiovascular benefits: a real-world study" </strong></p><p>Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown cardiovascular benefits in cardiovascular outcome trials in type 2 diabetes mellitus. However, the most convincing evidence was obtained in subjects with established cardiovascular (CV) disease. We analyzed the determinants of GLP-1 RA-mediated CV protection in a real-world population of persons with type 2 diabetes with and without a history of CV events with long-term follow-up.</p><p>Methods: Retrospective cohort study of 550 individuals with type 2 diabetes (395 in primary CV prevention, 155 in secondary CV prevention), followed at a single center after the first prescription of a GLP-1 RA between 2009 and 2019. CV and metabolic outcomes were assessed.</p><p>Results: Median duration of follow-up was 5.0 years (0.25-10.8) in primary prevention and 3.6 years (0-10.3) in secondary prevention, with a median duration of treatment of 3.2 years (0-10.8) and 2.5 years (0-10.3) respectively. In the multivariable Cox regression model considering GLP-1 RA treatment as a time-dependent covariate, in the primary prevention group, changes in BMI and glycated hemoglobin did not have an impact on MACE risk, while age at the time of GLP-1 initiation (HR 1.08, 95% CI 1.03-1.14, p = 0.001) and GLP-1 RA cessation by time (HR 3.40, 95% CI 1.82-6.32, p < 0.001) increased the risk of MACE. Regarding the secondary prevention group, only GLP-1 RA cessation by time (HR 2.71, 95% CI 1.46-5.01, p = 0.002) increased the risk of MACE. With respect to those who withdrew treatment, subjects who continued the GLP-1 RA had significantly greater weight loss and lower glycated hemoglobin levels during follow-up.</p><p>Conclusions: In this real-world type 2 diabetes population, discontinuation of GLP-1 RA treatment was associated to a higher risk of major cardiovascular events, in both subjects with and without a history of CV events.</p><p> </p>
Proteomic and metabolomic profiling underlines the stage- and time-dependent effects of high temperature on grape berry metabolism
<p>Supplementary figures and Tables from Lecourieux's manuscript submitted to IJMS</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.