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2,009 results for “Disruption”

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geo24/100

NOTCH2 disrupts the synovial fibroblast identity and the inflammatory response of epiphyseal chondrocytes [scRNA-Seq]

GEO Series GSE292807. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [RNA-seq]

GEO Series GSE226002. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo24/100

A germline ETV6 mutation disrupts hematopoiesis via de novo creation of a nuclear export signal

GEO Series GSE287784. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo24/100

Azithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation

GEO Series GSE208399. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenAug 2022View details →
geo24/100

Placental effects on maternal brain revealed by disrupted placental gene expression in mouse hybrids

GEO Series GSE126469. Mus musculus domesticus x Mus spretus; Mus spretus; Mus musculus domesticus. 44 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2019View details →
geo24/100

Global early replication disrupts gene expression and chromatin conformation in a single cell cycle: targeted origin deletion

GEO Series GSE199448. Saccharomyces cerevisiae. 48 samples. Type: Other.

openGEO-OpenSep 2022View details →
geo24/100

Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus

GEO Series GSE35829. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2012View details →
geo24/100

Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure

GEO Series GSE241486. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo24/100

Obesity Disrupts the Pituitary-Hepatic UPR Communication Leading to NAFLD Progression (pituitary scRNA seq)

GEO Series GSE263189. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

­­­Loss of Snhg5 disrupts cell-cycle regulation without altering cystogenesis in a mouse model of polycystic kidney disease.

GEO Series GSE300255. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

Converging Effects of Three Different Endocrine Disrupters on Sox and Pou Gene Expression in Developing Rat Hippocampus: Possible Role of microRNA in Sex Differences

GEO Series GSE180054. Rattus norvegicus. 66 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo24/100

Disruption of miRNA Sequence by TALENs and CRISPR/Cas9 Induces Varied Length of miRNA Production [TALENs]

GEO Series GSE130239. Oryza sativa. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenApr 2019View details →
geo24/100

Retinoic acid disrupts an NPM1c/ROS/SENP3/ARF oncogenic axis in acute myeloid leukemia

GEO Series GSE298593. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2025View details →
geo24/100

Disruption of Autism Spectrum Disorder-Susceptibility Genes Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

GEO Series GSE107878. Homo sapiens. 86 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2018View details →
geo24/100

KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells

GEO Series GSE146769. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2020View details →
geo24/100

Spliceosomal disruption of the non-canonical BAF complex in cancer

GEO Series GSE124720. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJun 2019View details →
geo24/100

Nicotine exposure declines quality of early embryos and disrupts placental structure by destabilizing Notch signaling pathway

GEO Series GSE186660. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.

GEO Series GSE101300. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2018View details →
geo24/100

Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

GEO Series GSE251849. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2024View details →
geo24/100

Airway Aging and Methylation Disruptions in HIV-associated Chronic Obstructive Pulmonary Disease [methylation]

GEO Series GSE178808. Homo sapiens. 76 samples. Type: Methylation profiling by genome tiling array.

openGEO-OpenMar 2022View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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