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2,009 results for “Disruption”

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geo24/100

CEBPA Dysfunction Intiates CSF3R Mutant Acute Myeloid Leukemia Through Disruption of Myeloid Lineage Enhancers (RNA-seq - orders)

GEO Series GSE122163. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2019View details →
geo24/100

Disrupted development and altered hormone signaling in male Padi2/Padi4 double knockout mice

GEO Series GSE194034. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2022View details →
geo24/100

Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in a Human Neural Stem Cell Model of Huntington’s Disease

GEO Series GSE74201. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2015View details →
geo24/100

Landscape of enhancer disruption and functional screen in melanoma [HiChIP]

GEO Series GSE210423. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 1]

GEO Series GSE108521. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2018View details →
geo24/100

Vitamin E deficiency disrupts gene expression networks during zebrafish development

GEO Series GSE164848. Danio rerio. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

Complement factor C1q mediates sleep spindle disruption and epileptic spikes after mild brain injury

GEO Series GSE179541. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2021View details →
geo24/100

Inhibition of TGF-β/Smad3 signaling disrupts cardiomyocyte cell cycle progression and EMT-like migration during ventricle regeneration

GEO Series GSE162820. Danio rerio. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2021View details →
geo24/100

Insulin resistance disrupts midbrain metabolic and functional homeostasis and aggravates dopaminergic neuron loss in GBA-PD via FOXO1 overexpression [WTvsGBA]

GEO Series GSE237115. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo24/100

TNFSF13 insuffiency causes epithelial and immune disruption in the human colon I

GEO Series GSE243443. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2024View details →
geo24/100

Targeted disruption of DNMT1, 3A and 3B in human embryonic stem cells [WGBS]

GEO Series GSE63278. Homo sapiens. 7 samples. Type: Methylation profiling by high throughput sequencing.

openGEO-OpenMar 2015View details →
geo24/100

Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation: MNase-seq data

GEO Series GSE22119. Drosophila melanogaster. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenOct 2010View details →
geo24/100

Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility

GEO Series GSE234050. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2023View details →
geo24/100

Disruption of Immune Responses By Type I Diabetes Exacerbates SARS-CoV-2 Mediated Lung Injury [scRNA-seq]

GEO Series GSE276765. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2024View details →
geo24/100

Long-term exposure to low-concentrations of Cr(VI) induce DNA damage and disrupt the transcriptional response to benzo[a]pyrene

GEO Series GSE49571. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2013View details →
geo24/100

Loss of Su(var)3-9 and SetDB1 disrupts late stages of larval development of Drosophila

GEO Series GSE223579. Drosophila melanogaster. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo24/100

Targeting HASPIN kinase disrupts SR protein-mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML

GEO Series GSE281301. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56

GEO Series GSE76023. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2016View details →
geo24/100

Reduced histone gene copy number disrupts Drosophila Polycomb function

GEO Series GSE228058. Drosophila melanogaster. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2023View details →
geo24/100

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β-cell function [ChIPseq]

GEO Series GSE182933. Rattus norvegicus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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