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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq]
GEO Series GSE101788. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
TGF-β signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
GEO Series GSE225636. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
Disruption of Actin Dynamics Regulated by Rho Effector mDia1 Attenuates Pressure Overload-Induced Cardiac Hypertrophic Responses and Exacerbates Dysfunction
GEO Series GSE142697. Mus musculus. 2 samples. Type: Expression profiling by array.
Disruption of BCAAs degradation is the primary mechanism of diabetic cardiomyopathy revealed by integrated transcriptome and metabolome analysis
GEO Series GSE267352. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [Long read sequencing]
GEO Series GSE225992. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification.
GEO Series GSE165951. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Disrupting YAP phase separation attenuates the development of primary liver cancer in animal models
GEO Series GSE277433. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
TNF-induced ArhGEF10 activates RhoB in human endothelial cells and contributes to tight junction disruption and barrier breakdown
GEO Series GSE161021. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity
GEO Series GSE207405. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modifications [eCLIP-seq]
GEO Series GSE278893. Mus musculus. 140 samples. Type: Other.
Selective Disruption of Core Regulatory Transcription
GEO Series GSE120771. Homo sapiens; Mus musculus. 109 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Genomic context sensitizes regulatory elements to genetic disruption [RNA]
GEO Series GSE254963. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes [RNA-seq]
GEO Series GSE181828. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Stimulation of immunity-linked genes by membrane disruption is linked to Golgi function and the ARF-1 GTPase
GEO Series GSE242371. Caenorhabditis elegans. 4 samples. Type: Expression profiling by high throughput sequencing.
Impact of exposures to persistent endocrine disrupting compounds on the sperm methylome in regions associated with neurodevelopmental disorders
GEO Series GSE165915. Homo sapiens. 52 samples. Type: Methylation profiling by high throughput sequencing.
LSD1 inhibitor T-3775440 inhibits SCLC cell proliferation by disrupting LSD1 interactions with SNAG domain proteins INSM1 and GFI1B
GEO Series GSE100169. Homo sapiens. 18 samples. Type: Expression profiling by array.
Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors
GEO Series GSE183064. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption
GEO Series GSE230493. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Human Respiratory Syncytial Virus Non-Structural Protein NS1 enters the nucleus to disrupt gene transcription (RNA-seq)
GEO Series GSE155151. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
The inflammatory micro-environment induced by targeted CNS radiotherapy is underpined by disruption of DNA methylation [Array]
GEO Series GSE264703. Homo sapiens. 34 samples. Type: Methylation profiling by genome tiling array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.