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Figure 21 in Atlas of Myriapod Biogeography. I. Indigenous Ordinal and Supra-Ordinal Distributions in the Diplopoda: Perspectives on Taxon Origins and Ages, and a Hypothesis on the Origin and Early Evolution of the Class
Figure 21. Distribution of Polyzoniida in Europe and the Middle East.
Figure 18 in Atlas of Myriapod Biogeography. I. Indigenous Ordinal and Supra-Ordinal Distributions in the Diplopoda: Perspectives on Taxon Origins and Ages, and a Hypothesis on the Origin and Early Evolution of the Class
Figure 18. Distribution of Platydesmida in North America/the Western Hemisphere.
Figure 17 in Atlas of Myriapod Biogeography. I. Indigenous Ordinal and Supra-Ordinal Distributions in the Diplopoda: Perspectives on Taxon Origins and Ages, and a Hypothesis on the Origin and Early Evolution of the Class
Figure 17. Distribution of the Order Platydesmida.
Figure 26 in Atlas of Myriapod Biogeography. I. Indigenous Ordinal and Supra-Ordinal Distributions in the Diplopoda: Perspectives on Taxon Origins and Ages, and a Hypothesis on the Origin and Early Evolution of the Class
Figure 26. Distribution of the Order Julida.
SARS-CoV-2 viral loads across the upper and lower respiratory tract, sex, disease severity and age groups for adult and pediatric COVID-19
<p>This dataset shows SARS-CoV-2 respiratory viral loads (viral RNA concentration in the respiratory tract) in the upper and lower respiratory tract for age, sex and COVID-19 severity groups. The data were obtained from a systematic review. The model outputs show the Weibull distributions, case percentiles, and sensitivity & specificity when using SARS-CoV-2 viral load (URT or LRT) as a prognostic indicator. See our paper for more information.</p>
Figure 3 in Population dynamics, age structure and sex ratio of the bromeliad-dwelling jumping spider, Psecas chapoda (Salticidae)
Figure 3. Climatic data from Itauna farm (5 km from the study site), from May 1998 to April 2000.
FGF-2-dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis
<p><span><span><span><span><span><span><span><span><span><span><span>Aged skeletal muscle is markedly affected by fatty muscle infiltration and strategies to reduce the occurrence of intramuscular adipocytes are urgently needed. Here, we show that fibroblast growth factor-2 (FGF-2) not only stimulates muscle growth, but also promotes intramuscular adipogenesis. Using multiple screening assays upstream and downstream of microRNA (miR)-29a signaling, we located the secreted protein and adipogenic inhibitor SPARC to an FGF-2 signaling pathway that is conserved between skeletal muscle cells from mice and humans and that is activated in skeletal muscle of aged mice and humans. FGF-2 induces the miR-29a/SPARC axis through transcriptional activation of FRA-1, which binds and activates an evolutionary conserved AP-1 site element proximal in the miR-29a promoter. Genetic deletions in muscle cells and AAV-mediated overexpression of FGF-2 or SPARC in mouse skeletal muscle revealed that this axis regulates differentiation of fibro/adipogenic progenitors <i>in vitro</i> and intramuscular adipose tissue (IMAT) formation <i>in vivo</i>. Skeletal muscle from human donors aged > 75 years versus < 55 years showed activation of FGF-2-dependent signaling and increased IMAT. Thus, our data highlights a disparate role of FGF-2 in adult skeletal muscle and reveals a novel pathway to combat fat accumulation in aged human skeletal muscle.</span></span></span></span></span></span></span></span></span></span></span></p>
Temporal and regional trends of antibiotic use in long-term aged care facilities across 39 countries, 1985-2019: systematic review and meta-analysis
<p><b>Background</b></p> <p>Antibiotic misuse is a key contributor to antimicrobial resistance and a concern in long-term aged care facilities (LTCFs). Our objectives were to: i) summarise key indicators of systemic antibiotic use and appropriateness of use, and ii) examine temporal and regional variations in antibiotic use, in LTCFs (PROSPERO registration CRD42018107125).</p> <p><b>Methods & Findings</b></p> <p>Medline and EMBASE were searched for studies published between 1990-2021 reporting antibiotic use rates in LTCFs. Random effects meta-analysis provided pooled estimates of antibiotic use rates (percentage of residents on an antibiotic on a single day [point prevalence] and over 12 months [period prevalence]; percentage of appropriate prescriptions). Meta-regression examined associations between antibiotic use, year of measurement and region. </p> <p>A total of 90 articles representing 78 studies from 39 countries with data between 1985-2019 were included. Pooled estimates of point prevalence and 12-month period prevalence were 5.2% (95% CI: 3.3-7.9; n=523,171) and 62.0% (95% CI: 54.0-69.3; n=946,127), respectively. Point prevalence varied significantly between regions (Q=224.1, df=7, p<0.001), and ranged from 2.4% (95% CI: 1.7-2.7) in Eastern Europe to 9.0% in the British Isles (95% CI: 7.6-10.5) and Northern Europe (95% CI: 7.7-10.5). Twelve-month period prevalence varied significantly between region (Q=15.1, df-3, p=0.002) and ranged from 53.9% (95% CI: 48.3-59.4) in the British Isles to 68.3% (95% CI: 63.6-72.7) in Australia. Meta-regression found no association between year of measurement and antibiotic use prevalence. The pooled estimate of the percentage of appropriate antibiotic prescriptions was 28.5% (95% CI: 10.3-58.0; n=17,245) as assessed by the McGeer criteria. Year of measurement was associated with decreasing appropriateness of antibiotic use over time (OR: 0.78, 95% CI: 0.67-0.91). The most frequently used antibiotic classes were penicillins (n=44 studies), cephalosporins (n=36), sulphonamides/trimethoprim (n=31), and quinolones (n=28). </p> <p><b>Conclusions</b></p> <p>Coordinated efforts focusing on LTCFs are required to address antibiotic misuse in LTCFs. Our analysis provides overall baseline and regional estimates for future monitoring of antibiotic use in LTCFs. </p>
database/Fornix volumetric increase and microglia morphology contribute to spatial and recognition-like memory decline during ageing
<p>Published along with the journal paper: Fornix volumetric increase and microglia morphology contribute to spatial and recognition-like memory decline during ageing</p>
FIG. 12 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 12. Looking south toward Red Rum (arrow) at the intermediate white beds of Zos Canyon.
FIG. 13 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 13. The Red Rum sublocality, looking west-southwest.
FIG. 14 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 14. Looking northwest from the Red Rum sublocality toward the discovery site (arrow).
FIG. 11 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 11. Looking south at the basalmost fluvial red sands at Zos Canyon.
FIG. 7 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 7. Ventral view of the preserved dorsal vertebrae of IGM 100/3181. Anterior is to the right.
FIG. 5 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 5. The radius (top) and ulna (bottom) of IGM 100/3181.
FIG. 2. IGM 100 in A new specimen of the ornithischian dinosaur Haya griva, cross-Gobi geologic correlation, and the age of the Zos Canyon beds
FIG. 2. IGM 100/3181, a partial skeleton of Haya griva.
Fig. 3 in An Early Miocene Dome-Skulled Chalicothere from the ''Arikaree'' Conglomerates of Darton: Calibrating the Ages of High Plains Paleovalleys Against Rocky Mountain Tectonism
Fig. 3. Geologic crosssection from Spoon
Fig. 5 in Gomphos elkema (Glires, Mammalia) from the Erlian Basin: Evidence for the Early Tertiary Bumbanian Land Mammal Age in Nei-Mongol, China
Fig. 5. Lower teeth of Gomphos elkema. A–C. Occlusal, lingual, and labial views of right m1–m3
Fig. 6 in Gomphos elkema (Glires, Mammalia) from the Erlian Basin: Evidence for the Early Tertiary Bumbanian Land Mammal Age in Nei-Mongol, China
Fig. 6. Lower teeth of Gomphos elkema. A–B. Occlusal views of left and right m1–m3, respectively
Fig. 1 in Gomphos elkema (Glires, Mammalia) from the Erlian Basin: Evidence for the Early Tertiary Bumbanian Land Mammal Age in Nei-Mongol, China
Fig. 1. Locality map of the Erlian Basin (after Meng et al., 1998).
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.