Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
3,947
datasets available to search
ShareScore release 0.9.0
Dataset results
3,947 results for “Requirement”
Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin accessibility and looping [RNA-Seq 2]
GEO Series GSE156306. Homo sapiens; Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
GEO Series GSE21503. Danio rerio. 5 samples. Type: Non-coding RNA profiling by high throughput sequencing.
cis-Regulatory Requirements for Tissue-Specific Programs of the Circadian Clock
GEO Series GSE40467. Drosophila melanogaster. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The TFIID subunit TAF4 is required for pancreatic beta cell function and identity [single-cell RNA-seq]
GEO Series GSE151365. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells
GEO Series GSE124409. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
Sox2 is required for global chromatin interactions in brain-derived neural stem cells [ChIP-seq]
GEO Series GSE90559. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
H3K27me3 is dispensable for early differentiation but required to maintain differentiated cell identity
GEO Series GSE151486. Mus musculus. 69 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
A Genome-wide RNAi screen identifies factors required for distinct stages of C. elegans piRNA biogenesis
GEO Series GSE53970. Caenorhabditis elegans. 34 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Ibf1 and Ibf2 are DNA-binding proteins required for insulator function in Drosophila [ChIP-seq]
GEO Series GSE46614. Drosophila melanogaster. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MLL3/4 Direct a Gene-expression Program Required for Efficient Platelet Production [RNA-seq]
GEO Series GSE255020. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Myocardin-related Transcription Factors Are Required for Skeletal Muscle Development
GEO Series GSE84063. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
HexSDF are Required for Synthesis of a Novel Glycolipid that Mediates Daptomycin and Bacitracin Resistance in C. difficile
GEO Series GSE220119. Clostridioides difficile. 6 samples. Type: Expression profiling by high throughput sequencing.
Isha is a su(Hw) mRNA-binding protein required for insulator function [ChIP-seq]
GEO Series GSE200993. Drosophila melanogaster. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Lmx1b is required at multiple stages to build expansive serotonergic axon architectures
GEO Series GSE130514. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
GATA2 mitotic bookmarking is required for definitive haematopoiesis [ChIP-seq]
GEO Series GSE207551. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
PDK1 is required for maintenance of CD4+ FoxP3+ regulatory T cell function [heterozygous]
GEO Series GSE163659. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
WDR5 is required for DUX4 expression and its pathological effects in FSHD muscular dystrophy
GEO Series GSE210610. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
KMT2B is selectively required for neuronal transdifferentiation [RNAseq]
GEO Series GSE120440. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline
GEO Series GSE154209. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Identification of required host factors for SARS-CoV-2 infection in human cells [RNA-seq]
GEO Series GSE159522. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.