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13,587 results for “specification”
Guidelines for applicants to service - CYBERSTAND.eu Specific Service Procedure
<p>This document provides the main guidelines for applicants who are interested in applying for CYBERSTAND.<br>eu Specific Service Procedures (SSPs).<br>In a series of six cycles, running until November 2026, CYBERSTAND.eu will assign a total of € 1.500,000<br>to acquire services to address Cyber Resilience Act (CRA) related standardisation priorities.<br>The objective is to enable the specialists to contribute to and help create a fully integrated European<br>Standardisation Ecosystem, thereby strengthening Europe’s position in global standardisation initiatives.</p>
Disease-specific antibody databases for bottom-up proteomics
<p>Heavy chains of antibody sequences were collected from the <a href="https://opig.stats.ox.ac.uk/webapps/oas/">OAS database</a>, and then digested into trypic peptides (enzym: tryptic, miscleavage: 2).</p> <p>Tryptic peptides that were exclusive to each disease and not available in public protein databases (e.g., UniProt and NCBI-RefSeq) were retained to form the final data files.</p> <p> </p> <p> </p>
F in Seed-infesting chalcids of the genus Megastigmus Dalman, 1820 (Hymenoptera: Torymidae) native and introduced to the West Palearctic region: taxonomy, host specificity and distribution
F. 5. Lateral view of thorax, M. suspectus, ex. Abies alba, Poland. acr, acropleuron; ax,
Text-fig. 1. Map of Turkey showing the localities Keseköy, Yapıntı and Horlak. in An Exceptional Large Sample Of The Early Miocene Ctenodactyline Rodent Sayimys Giganteus, Specific Variation And Taxonomic Implications
Text-fig. 1. Map of Turkey showing the localities Keseköy, Yapıntı and Horlak.
Dataset related to article "Nasal Polyposis Quality of Life (NPQ): Development and Validation of the First Specific Quality of Life Questionnaire for Chronic Rhinosinusitis with Nasal Polyps "
<p>This record contains raw data related to article “Nasal Polyposis Quality of Life (NPQ): Development and Validation of the First Specific Quality of Life Questionnaire for Chronic Rhinosinusitis with Nasal Polyps"</p> <p>Abstract</p> <p>To date, no disease-specific tool has been available to assess the impact of chronic rhinosinusitis with nasal polyps (CRSwNP) on health-related quality of life (HRQoL). Therefore, the purpose of this study was to develop and validate a questionnaire specifically designed to this aim: the Nasal Polyposis Quality of Life (NPQ) questionnaire. As indicated in the current guidelines, the development and validation of the NPQ occurred in two separate steps involving different groups of patients. The questionnaire was validated by assessing internal structure, consistency, and validity. Responsiveness and sensitivity to changes were also evaluated. In the development process of NPQ an initial list of 40 items was given to 60 patients with CRSwNP; the 27 most significant items were selected and converted into questions. The validation procedure involved 107 patients (mean age 52.9 ± 12.4). NPQ revealed a five-dimensional structure and high levels of internal consistency (Cronbach's alpha 0.95). Convergent validity (Spearman' coefficient r = 0.75; <em>p</em> < 0.01), discriminant validity (sensitivity to VAS score), and reliability in a sample of patients with a stable health status (Interclass Coefficient 0.882) were satisfactory. Responsiveness to clinical changes was accomplished. The minimal important difference was 7. NPQ is the first questionnaire for the assessment of HRQoL in CRSwNP. Our results demonstrate that the new tool is valid, reliable, and sensitive to individual changes.</p>
Dataset related to article "A comprehensive investigation of histotype-specific microRNA and their variants in stage I epithelial ovarian cancers"
<p>This record contains data related to article “A comprehensive investigation of histotype-specific microRNA and their variants in stage I epithelial ovarian cancers".</p> <p>isomiRs, the sequence-variants of microRNA, are known to be tissue and cell type specific but their physiological role is largely unknown. In this study we explored for the first time the expression of isomiRs across different stage I epithelial ovarian cancer (EOC) histological subtypes, in order to shed new light on their biological role in tumor growth and progression. In a multi-centric retrospective cohort of tumor biopsies (n=215) we sequenced small RNAs finding 971 expressed miRNAs, 64% of which are isomiRs. Among them, 42 isomiRs showed a clear histotype specific pattern, confirming our previously identified miRNA markers (miR192/194 and miR30a-3p/5p for mucinous and clear cell subtypes respectively) and uncovering new biomarkers for all the five subtypes. Using integrative models, we found that the 38% of these miRNA expression alterations is the result of copy number variations while the 17% of differential transcriptional activities. Our work represents the first attempt to characterize isomiRs expression in stage I EOC within and across subtypes and to contextualize their alterations in the framework of the large genomic heterogeneity of this tumor.</p>
To Validate the Specific Patterns of Magnetocardiography, a Non-invasive Non-contact Examination for Patients With Ischemic Heart Disease or Cardiac Arrhythmia
ClinicalTrials.gov study NCT00965614. IPD Sharing: Not stated. Countries: 0. Publications: 0.
CTL019 Out of Specification MAP for ALL or DLBCL Patients
ClinicalTrials.gov study NCT03601442. IPD Sharing: Not stated. Countries: 3. Publications: 0.
Prevention of Falls in Older Adults by Specific and Progressive Balance Training
ClinicalTrials.gov study NCT03464825. IPD Sharing: NO. Countries: 0. Publications: 0.
Afatinib (GILOTRIF®) in Patients Suffering From Tumors Harboring Neuregulin 1 (NRG1) Gene Alterations (Specifically NRG1 Gene Fusion-positive Advanced Solid Tumors)
ClinicalTrials.gov study NCT05107193. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Strand-specific DNA:RNA immunoprecipitation sequencing on T-47D breast cancer cells.
GEO Series GSE193225. Homo sapiens. 2 samples. Type: Other.
Transcription factor HMGA2 controls the K-RAS mediated transformation-specific genetic program
GEO Series GSE14658. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
De novo methylation enforces long-term lineage-specific programing of TFH and TH1 memory cells [WGBS]
GEO Series GSE168398. Mus musculus. 10 samples. Type: Methylation profiling by high throughput sequencing.
Microglia-specific loss of PU.1 function rescues neurodegenerative phenotypes in a mouse model of Alzheimer’s disease
GEO Series GSE117868. Mus musculus. 19 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Drought Recovery in Plants Triggers a Cell-State Specific Immune Activation [snRNA-Seq]
GEO Series GSE220277. Arabidopsis. 14 samples. Type: Expression profiling by high throughput sequencing.
Effect of cardiac specific KO of p38 MAPKα on gene expression profile of the heart
GEO Series GSE86075. Mus musculus. 7 samples. Type: Expression profiling by array.
The ALOG domain defines a new family of plant-specific transcription factors acting during Arabidopsis flower development
GEO Series GSE235674. Arabidopsis thaliana. 8 samples. Type: Other.
Dynamic DNA methylation turnover at the exit of pluripotency epigenetically primes gene regulatory elements for hematopoietic lineage specification [ChIP]
GEO Series GSE223569. Mus musculus. 131 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Specific multivalent molecules boost CRISPR-mediated transcriptional activation via optimal cis-trans interaction and functional chromatin looping [RNA-seq]
GEO Series GSE248523. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide binding reveals intrinsic specificity and regulatory function of lineage-specifying bHLH transcription factors (RNA-Seq).
GEO Series GSE97713. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.