Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Disruption of the Integrator complex triggers the Integrated Stress Response through formation of double-stranded RNA [RIPseq]
GEO Series GSE267044. Homo sapiens. 10 samples. Type: Other.
Elevated Endothelial Sox2 Causes Lumen Disruption and Cerebral AVMs
GEO Series GSE129644. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption of Nipbl/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome
GEO Series GSE145966. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA-Seq analysis of WT and BbTdp1 disruption strain in Beauveria bassiana
GEO Series GSE179456. Beauveria bassiana ARSEF 2860. 6 samples. Type: Expression profiling by high throughput sequencing.
Combined epigenetic therapy with FACT and BET inhibitors remodels chromatin and disrupts oncogenic transcription in Diffuse Midline Glioma [ATAC-seq]
GEO Series GSE272129. Homo sapiens. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Human ZNF341 deficiency underlies a recessive form of hyper IgE syndrome by disrupting STAT3 transcription-dependent STAT3 activity
GEO Series GSE113945. Homo sapiens. 11 samples. Type: Expression profiling by array.
Targeted disruption of glycerol kinase gene in mice: expression analysis in liver
GEO Series GSE3843. Mus musculus. 8 samples. Type: Expression profiling by array.
Disruptions of Topological Chromatin Domains Causes Pathogenic Rewiring of Gene-Enhancer Interactions [4C-Seq-human]
GEO Series GSE66378. Homo sapiens. 6 samples. Type: Other.
Disruption of ARID1B recruitment to the nuclear pore complex as a new anticancer therapeutic strategy [ATAC-seq]
GEO Series GSE274400. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer [ATAC]
GEO Series GSE239645. human gammaherpesvirus 4. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Brain samples in a metamorphosis assay for thyroid axis disruption
GEO Series GSE7189. Aquarana catesbeiana; Xenopus laevis. 124 samples. Type: Expression profiling by array.
LSD1 inhibition disrupts super-enhancer activities in CRPC [ChIP-seq]
GEO Series GSE209886. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Transcriptomic Characterization Reveals Disrupted Medium Spiny Neuron Trajectories in Huntington's Disease and Possible Therapeutic Avenues
GEO Series GSE232649. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Disruption of the Nα-acetyltransferase NatB causes sensitivity to reductive stress in Arabidopsis thaliana
GEO Series GSE186324. Arabidopsis thaliana. 6 samples. Type: Expression profiling by array.
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders [ChIP-seq]
GEO Series GSE210465. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation
GEO Series GSE20472. Drosophila melanogaster. 30 samples. Type: Genome binding/occupancy profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [NTD-Seq]
GEO Series GSE254796. Homo sapiens. 12 samples. Type: Other.
Targeting KDM4B to disrupt the core regulatory transcription network governed by PAX3-FOXO1 in high-risk rhabdomyosarcoma [ChIP-seq]
GEO Series GSE157094. Homo sapiens. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption
GEO Series GSE213149. Homo sapiens. 120 samples. Type: Other.
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [scRNA-seq]
GEO Series GSE121429. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.