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13,017 results for “Positionning”
Profiling of H3K27ac positioning in primary erythroid cells by CUT&RUN
GEO Series GSE171385. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
NR2F2 is a key downstream effector of NF1 loss in estorgen receptor positive breast cancer (ChIP-seq)
GEO Series GSE217416. Homo sapiens. 52 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Androgen receptor is a back-door inhibitor of Androgen Receptor is a Backdoor Inhibitor of Wildtype and Mutant Estrogen Receptors in Refractory Hormone Receptor-Positive Breast Cancers
GEO Series GSE126318. Homo sapiens. 7 samples. Type: Expression profiling by array.
Study of gene expression following Pim2 knockdown in FLT3-ITD-positive acute myeloid leukemia
GEO Series GSE94870. Homo sapiens. 4 samples. Type: Expression profiling by array.
Immunohistochemical and transcriptional analysis uncover RasGRF2-mediated regulation of nestin-positive stem cell density and early neuronal differentiation in the dentate gyrus of the hippocampus of
GEO Series GSE98213. Mus musculus. 12 samples. Type: Expression profiling by array.
DE 1 8-sec Position Data
Two Dynamics Explorer (DE) spacecraft were launched August 3, 1981, and placed into coplanar polar orbits with DE-1 in a highly elliptical orbit and DE-2 in a lower more circular orbit. The primary objective of the DE program was to investigate magnetosphere-ionosphere-atmosphere coupling processes. The DE mission provided a wealth of new information on a wide variety of magnetospheric plasma wave phenomena including auroral kilometric radiation, auroral hiss, Z mode radiation, narrow-band electromagnetic emissions associated with equatorial upper hybrid waves, whistler mode emissions, wave-particle interactions stimulated by ground VLF transmitters, equatorial ion cyclotron emissions, ion Bernstein mode emissions, and electric field turbulence along the auroral field lines. These files contain 8 second resolution emphemeris and spacecraft attitude parameters that coincide with DE-1 telemetry frames containing PWI lowrate data. These parameters are not to be taken as an authoritative set, but are convenient when working with PWI science data products. Most of these data are provided in the Geocentric Equatorial Inertial (GEI) TOD reference frame. The Z axis of the GEI frame is parallel to Earth's spin axis; the X axis points towards the First Point of Aries with the Y axis aligned so as to generate a right-handed coordinate system.
CSSWE REPTile Level 1 6-s Counts and Position
This data set contains Level 1 corrected count rates from the Relativistic Electron and Proton Telescope integrated little experiment (REPTile)on board the Colorado Student Space Weather Experiment (CSSWE) CubeSat. Electron counts are provided for 0.5-1.7 MeV, 1.7-3.3 MeV, and >3.3 MeV. Proton counts are provided for 9-18 MeV, 19-30 MeV, and 30-40 MeV. All counts, in units of number per 6 seconds, have been corrected for transmission and temperature noise. L is calculated using the IGRF magnetic field model. Geographic latitude, longitude and altitude (km) are provided.
VOYAGER 2 JUPITER POSITION RESAMPLED DATA 48.0 SECONDS
This data set includes Voyager 2 Jupiter encounter position data that have been generated at a 48.0 second sample rate using the NAIF SPICE kernals. The data set is composed of 4 columns: 1) ctime - this column contains the data acquisition time. The time is always output in the ISO standard spacecraft event time format (yyyy-mm-dd-Thh:mm:ss.sss) but is stored internally in Cline time which is measured in seconds after 00:00:00.000 Jan 01, 1966, 2) r - this column contains the radial distance from Jupiter in Rj = 71398 km, 3) longitude - this column contains the east longitude of the spacecraft in degrees, 4) latitude - this column contains the latitude of the spacecraft in degrees. Position data is given in Minus System III coordinates.
GALILEO CRUISE POSITION DATA (RTN COORDINATES)
This dataset contains the Galileo spacecraft trajectory during the interplanetary cruise. The data have been derived from SPICE kernels at a 1 minute sample rate. The data are provided in RTN coordinates.
VOYAGER 2 SATURN POSITION RESAMPLED DATA 48.0 SECONDS
This data set includes Voyager 2 Saturn encounter position data that have been generated at a 48.0 second sample rate using the NAIF SPICE kernals. The data set is composed of 4 columns: 1) ctime - this column contains the data acquisition time. The time is always output in the ISO standard spacecraft event time format (yyyy-mm-dd-Thh:mm:ss.sss) but is stored internally in Cline time which is measured in seconds after 00:00:00.000 Jan 01, 1966, 2) r - this column contains the radial distance from Saturn in Rs = 60330 km, 3) longitude - this column contains the east longitude of the spacecraft in degrees, 4) latitude - this column contains the latitude of the spacecraft in degrees. Position data is given in Minus Saturn Longitude System (kronographic) coordinates.
IRAS POSITION AND POINTING V1.0
This data presented with this data set includes: (a) The position of the satellite in its orbit about the Earth at 200 second intervals in heliocentric ecliptic rectangular coordinates (B1950), where the X axis points to the First Point of Ares. In addition an Earth ephemeris is also included, which was generated by Miles Standish at JPL using the information that was available in 1983 to best approximate the knowledge of the Earth's position that was used in the reduction of the IRAS data. Finally, the geocentric position of the satellite is calculated using the above information. (b) The IRAS Scan History File describes the pointing geometry and length of each survey-mode scan (by SOP OBS) over the entire mission.
VOYAGER 1 JUPITER POSITION RESAMPLED DATA 48.0 SECONDS
This data set includes Voyager 1 Jupiter encounter position data that have been generated at a 48.0 second sample rate using the NAIF SPICE kernals. The data set is composed of 4 columns: 1) ctime - this column contains the data acquisition time. The time is always output in the ISO standard spacecraft event time format (yyyy-mm-dd-Thh:mm:ss.sss) but is stored internally in Cline time which is measured in seconds after 00:00:00.000 Jan 01, 1966, 2) r - this column contains the radial distance from Jupiter in Rj = 71398 km, 3) longitude - this column contains the east longitude of the spacecraft in degrees, 4) latitude - this column contains the latitude of the spacecraft in degrees. Position data is given in Minus System III coordinates.
MPF LANDER MARS IMP STEREO-DERIVED 3D POSITIONS V1.0
This volume contains data from the Imager for Mars Pathfinder 3D Position data set.The data set consists of tables of three-dimensional spatial coordinates of each pixel in an IMP EDR stereo pair. The coordinates are derived from the Ames Stereo Pipeline, an automated machine vision algorithm that correlates features between the left and right images of stereo pairs to determine their disparity, then computes their position using the stereo camera properties
VOYAGER 1 SATURN POSITION RESAMPLED DATA 48.0 SECONDS
This data set includes Voyager 1 Saturn encounter position data that have been generated at a 48.0 second sample rate using the NAIF SPICE kernals. The data set is composed of 4 columns: 1) ctime - this column contains the data acquisition time. The time is always output in the ISO standard spacecraft event time format (yyyy-mm-dd-Thh:mm:ss.sss) but is stored internally in Cline time which is measured in seconds after 00:00:00.000 Jan 01, 1966, 2) r - this column contains the radial distance from Saturn in Rs = 60330 km, 3) longitude - this column contains the east longitude of the spacecraft in degrees, 4) latitude - this column contains the latitude of the spacecraft in degrees. Position data is given in Minus Saturn Longitude System (kronographic) coordinates.
Electrical Conductivity of Rocks and Dominant Charge Carriers: The Paradox of Thermally Activated Positive Holes
In this paper we have focused on fundamental processes that are important for understanding the electrical properties of materials, both single crystal minerals and igneous rocks, both laboratory-grown and from natural environments. The prevailing view in the geophysics community is that the electrical conductivity structure of the Earth’s continental crust over the 5-35 km depth range can best be understood by assuming the presence of intergranular fluids and/or intergranular carbon films. Based on studies of melt-grown MgO, magma-derived sanidine and anorthosite feldspar and upper mantle olivine single crystal we present evidence for the presence of electronic charge carriers, the importance of which has been largely ignored. These charge carriers derive from peroxy defects, which are introduced during cooling, under non-equilibrium conditions, through a redox conversion of pairs of solute OH– arising from the solid state dissolution of H2O. It can be shown that, during reheating, the peroxy defects become thermally activated in a 2-step process. Step 2 leads to the release of defect electrons in the oxygen anion sublattice. Known as positive holes and symbolized by h•, these electronic charge carriers are associated with energy states at the upper edge of the valence band. They are highly mobile. Chemically equivalent to O– in a matrix of O2– they are highly oxidizing. However, though metastable, the h• can exist in minerals, which crystallized in highly reduced environments. The h• appear to control the electrical conductivity of crustal rocks over much of the 5-35 km depth range. We make the extraordinary and seemingly paradoxial claim that MgO crystals, grown from the melt under the viciously reducing conditions of a carbon arc fusion furnace, contain peroxy defects in their crystal structure, hence oxygen in the valence state 1–. When the peroxy defects break up, they release positive hole charge carriers, formally defect electron in the oxygen anion sublattice, equivalent to O– in a matrix of O2–. These positive holes have two outstanding properties: they are highly mobile and highly oxidizing.
LP MOON SPACECRAFT POSITION V1.0
The Lunar Prospector spacecraft position data set consists of spacecraft position determinations in selenographic latitude, longitude, and altitude coordinates in one minute intervals. The data set also contains spacecraft velocity and distance from the center of the Moon as a function of time. The coordinate system is selenographic with east longitude positive. The data set is generated by the Goddard Flight Dynamics Analysis Branch.
Study of Tumor Recurrence Related to the Expression of the PAX3-FOXO1 Oncogenic Transcription Factor in Fusion-Positive Rhabdomyosarcoma
Alveolar rhabdomyosarcoma (ARMS) is a highly aggressive pediatric soft tissue cancer characterized by a recurrent 2;13 chromosome translocation. This translocation generates a PAX3-FOXO1 (P3F) fusion gene, which encodes a chimeric transcription factor with oncogenic activity. Using a human myoblast system that models targeted therapy directed against P3F, we demonstrated that the expression of the fibroblast growth factor 8 (FGF8), a direct transcriptional target of P3F, is necessary and sufficient for PAX3-FOXO1-independent tumor recurrence in addition to be required for the tumorigenic activity of primary tumors expressing P3F. In addition, we showed that FGF8 is expressed in human rhabdomyosarcoma cell lines that express P3F. We also demonstrated that FGF8 contributes to their proliferation and transformation in vitro, and is sufficient to maintain their oncogenicity after the loss of P3F expression. We suggest that targeting the expression of the PAX3-FOXO1 transcription factor can generate resistance and recommend that additional anticipated therapeutic approaches, such as targeting FGF8 pathway, may avoid this resistance mechanism.
Trastuzumab beyond progression in HER2-positive metastatic breast cancer
<p>The data about continuing trastuzumab treatment beyond progression in HER2-positive breast cancer are lacking in Iraq. This study aimed for investigating the use of trastuzumab in Iraqi women with metastatic HER2-positive breast cancer.</p> <p>A single-arm non-comparative observational prospective study was conducted in Oncology Teaching Hospital between 2013 and 2019. The study included metastatic HER2-positive breast cancer progressing after first-line chemotherapy plus trastuzumab.</p> <p>Only 16(27%) cases had tumor progression. Median time to progression was 16 months (95% CI:11.0–20.9). 55(93%) patients had a progression-free survival of ≥ 6 months, whereas 32(54%) had a progression-free survival of ≥ 12 months.</p> <p>The continuing trastuzumab beyond progression has clinical benefits in HER2-positive metastatic breast cancer.</p>
Development of emotional categorization of positive and negative faces.
<p>Biases in the processing of emotional facial expression have been the subject of much debate in the literature. Opposing views on this topic claim either that positive or negative facial expressions enjoy improved processing capabilities in the human brain. This disagreement may stem from examining different participant ages, and the use of various testing paradigms. Thus, the resulting findings may reflect differing aspects of facial emotion processing and therefore lead to differing results. To investigate the specific aspect of how rapidly an observer can access emotional valence information from a facial stimulus depending on the observer’s age and the original stimulus valence, we investigated different children’s age groups compared to adults with the same emotion categorization task in a single study. Six-, 9-, and 12-year-old children, as well as adults were asked to categorize various facial expressions as positive or negative as quickly as possible. Our results show an early age processing advantage for positive faces, which disappears in adults who show no such differences in the case of response time measures. In the case of accuracy measures, the early advantage for positive faces gradually disappears, and is in fact reversed into a negativity advantage in adults. These findings demonstrate that positive and negative processing advantages are strongly modulated by age, and can vary even within a single testing methodology depending on the developmental stage of the participant.</p>
Short-Term Effects of a Multidisciplinary Residential Rehabilitation Program on Perceived Risks, Confidence Toward Continuous Positive Airway Pressure Treatment, and Self-Efficacy in a Sample of Individuals Affected by Obstructive Sleep Apnea Syndrome.
<p>This dataset is related to the following article:</p> <p>Scarpina F, Bastoni I, Cappelli S, Priano L, Giacomotti E, Castelnuovo G, Molinari E, Tovaglieri IMA, Cornacchia M, Fanari P, Mauro A. Short-Term Effects of a Multidisciplinary Residential Rehabilitation Program on Perceived Risks, Confidence Toward Continuous Positive Airway Pressure Treatment, and Self-Efficacy in a Sample of Individuals Affected by Obstructive Sleep Apnea Syndrome. Front Psychol. 2021 Aug 18;12:703089. doi: 10.3389/fpsyg.2021.703089. PMID: 34484053; PMCID: PMC8416346.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.