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1,880
datasets available to search
ShareScore release 0.9.0
Dataset results
1,880 results for “Dimensionality”
High-dimensional single cell analysis reveals an effector Treg molecular program that correlates with lung cancer progression
GEO Series GSE128822. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion
GEO Series GSE148185. Homo sapiens. 275 samples. Type: Other; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Transcriptomic profile of three-dimensional tissue-engineered human skeletal muscle model of Pompe disease and recombinant protein therapy
GEO Series GSE159062. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Impact of microgravity on a three-dimensional microphysiologic culture of the human kidney proximal tubule epithelium: cell response to serum and vitamin D
GEO Series GSE268236. Homo sapiens. 73 samples. Type: Expression profiling by high throughput sequencing.
Mutational synergy coordinately remodels chromatin accessibility, enhancer landscape and 3-Dimensional DNA topology to alter gene expression during leukemia induction (pCHiC)
GEO Series GSE146662. Mus musculus. 10 samples. Type: Other.
Three-dimensional genome structures of single mammalian sperm [scHi-C]
GEO Series GSE276999. Homo sapiens; Mus musculus. 717 samples. Type: Other.
Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression
GEO Series GSE50199. Plasmodium falciparum 3D7. 4 samples. Type: Other.
Three-dimensional genomic structure and cohesin occupancy correlates with transcriptional activity during spermatogenesis
GEO Series GSE132054. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
Three-dimensional chromatin reorganization during CD8+ T cell activation is mediated by TRIM28
GEO Series GSE260940. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Dysregulated NK Cell Activation and Myeloid-Lymphoid Imbalance Underpin COPD Progression: Insights from High-Dimensional Immune Profiling and Smoking-Induced Immune Remodeling
GEO Series GSE306950. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
Comparison of spheroid-based 3-dimensional culture to monolayer of larynx carcinoma cell line HLaC78.
GEO Series GSE67495. Homo sapiens. 2 samples. Type: Expression profiling by array.
Three-dimensional genome architectural CCCTC-binding factor makes choice in duplicated enhancers at Pcdhα locus. [ChIP-seq II]
GEO Series GSE147279. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
High Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune Checkpoint Cancer Therapy
GEO Series GSE119352. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Three-dimensional chromatin landscapes in MLLr AML [RNA-Seq]
GEO Series GSE244470. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Three-dimensional hydraulic tomography analysis of long-term municipal wellfield operations: Validation with synthetic flow and solute transport data
<p>Attached are the datasets utilized to accomplish the study of "<em>Three-dimensional hydraulic tomography analysis of long-term municipal wellfiled operations: Validation with synthetic flow and solute transport data". </em>Basically, it includes the information of the discrete model and assigned, wells as well as the generated synthetic hydraulic head and solute concentration data.</p>
Supplementary Data: Cloud-based multi-dimensional parallel dynamic programming algorithm for a hydropower station system
<p>The files in this record contain data for cloud-based multi-dimensional parallel dynamic programming algorithm for a hydropower station system considered for publication in Water Resources Research.</p> <p>The files consist of:</p> <ul> <li>cascade reservoir system data;</li> <li>Source code and results of the parallel dynamic programming algorithm program on the physical machine;</li> <li>Source code and results of the parallel dynamic programming algorithm program on the cloud virtual machine;</li> </ul>
Multi-dimensional Toy Data
<p>Dataset taken from https://sites.google.com/view/mstamp</p> <p>Stored on Zenodo as backup for Stumpy Multi-dimensional Matrix Profiles</p>
Data from: Encounter complexes and dimensionality reduction in protein-protein association
An outstanding challenge has been to understand the mechanism whereby proteins associate. We report here the results of exhaustively sampling the conformational space in protein–protein association using a physics-based energy function. The agreement between experimental intermolecular paramagnetic relaxation enhancement (PRE) data and the PRE profiles calculated from the docked structures shows that the method captures both specific and non-specific encounter complexes. To explore the energy landscape in the vicinity of the native structure, the nonlinear manifold describing the relative orientation of two solid bodies is projected onto a Euclidean space in which the shape of low energy regions is studied by principal component analysis. Results show that the energy surface is canyon-like, with a smooth funnel within a two dimensional subspace capturing over 75% of the total motion. Thus, proteins tend to associate along preferred pathways, similar to sliding of a protein along DNA in the process of protein-DNA recognition.
Data from: From the cover: three-dimensional (3d) heparg spheroid model with physiologically relevant xenobiotic metabolism competence and hepatocyte functionality for liver toxicity screening.
Effective prediction of human responses to chemical and drug exposure is of critical importance in environmental toxicology research and drug development. While significant progress has been made to address this challenge using invitro liver models, these approaches often fail due to inadequate tissue model functionality. Herein, we describe the development, optimization, and characterization of a novel three-dimensional (3D) spheroid model using differentiated HepaRG cells that achieve and maintain physiologically relevant levels of xenobiotic metabolism (CYP1A2, CYP2B6, and CYP3A4/5). This invitro model maintains a stable phenotype over multiple weeks in both 96- and 384-well formats, supports highly reproducible tissue-like architectures and models pharmacologically- and environmentally important hepatic receptor pathways (ie AhR, CAR, and PXR) analogous to primary human hepatocyte cultures. HepaRG spheroid cultures use 50–100× fewer cells than conventional two dimensional cultures, and enable the identification of metabolically activated toxicants. Spheroid size, time in culture and culture media composition were important factors affecting basal levels of xenobiotic metabolism and liver enzyme inducibility with activators of hepatic receptors AhR, CAR and PXR. Repeated exposure studies showed higher sensitivity than traditional 2D cultures in identifying compounds that cause liver injury and metabolism-dependent toxicity. This platform combines the well-documented impact of 3D culture configuration for improved tissue functionality and longevity with the requisite throughput and repeatability needed for year-over-year toxicology screening.
Three-dimensional sediment dynamics in well-mixed estuaries: importance of the internally-generated overtide, spatial settling lag and gravitational circulation
<p>model outputs</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.