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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Adipocytes disrupt the translational programme of Acute Lymphoblastic Leukaemia to favour tumour survival and persistence
GEO Series GSE151802. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Disruption of histone methylation in developing sperm impairs offspring health transgenerationally [embryo]
GEO Series GSE66051. Mus musculus. 8 samples. Type: Expression profiling by array.
Targeting KDM4B to disrupt the core regulatory transcription network governed by PAX3-FOXO1 in high-risk rhabdomyosarcoma [ATAC-seq]
GEO Series GSE157092. Homo sapiens. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disrupted control of origin activation promotes genomic instability upon loss of POLE4 and disfunction of the TRP53-CDKN1A/P21 tumour suppressor axis.
GEO Series GSE200331. Mus musculus. 2 samples. Type: Other.
Targeting KDM4B to disrupt the core regulatory transcription network governed by PAX3-FOXO1 in high-risk rhabdomyosarcoma [CUT&RUN]
GEO Series GSE157093. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genomic and transcriptomic profiles underlying the effect of SETD1A disruption on human neurodevelopmental trajectories [ChIP-seq]
GEO Series GSE237297. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Activation of proto-oncogenes by disruption of chromosome neighborhoods [5C-Seq]
GEO Series GSE77142. Homo sapiens. 9 samples. Type: Other.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes [CUT&TAG]
GEO Series GSE222516. Homo sapiens. 29 samples. Type: Other.
Non-alcoholic steatohepatitis disrupts diurnal liver transcriptome rhythms in mice
GEO Series GSE217492. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
CRISPRi Screening of Enhancers in Human Primary Astrocytes Identifies Regulatory Circuitry Disrupted in Alzheimer’s Disease
GEO Series GSE252965. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Characterization of estrogen and the endocrine-disrupting chemical-induced mouse mammary gland reorganization via single-cell RNA-sequencing
GEO Series GSE125272. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeted p63 isoform modulation corrects dominant mutations in AEC syndrome without disrupting epidermal homeostasis [ChIP-seq]
GEO Series GSE297766. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis (RNA-Seq)
GEO Series GSE247992. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome Alterations Following Developmental Atrazine Exposure in Zebrafish Are Associated with Disruption of Neuroendocrine and Reproductive System Function, Cell Cycle, and Carcinogenesis
GEO Series GSE117398. Danio rerio. 12 samples. Type: Expression profiling by array.
Imatinib Disrupts Lymphoma Angiogenesis by Targeting Vascular Pericytes
GEO Series GSE30752. Mus musculus. 4 samples. Type: Expression profiling by array.
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer
GEO Series GSE234658. human gammaherpesvirus 4. 16 samples. Type: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A novel tumor suppressing role for RUNX3 is shown where a direct interaction with MYC leads to disruption of MYC-MAX heterodimers and consequent degradation of the MYC oncoprotein
GEO Series GSE233777. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [NTD-chIP-seq]
GEO Series GSE225997. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disrupting ATF4 expression mechanisms provides an effective strategy for BRAF-targeted melanoma therapy
GEO Series GSE136615. Homo sapiens. 14 samples. Type: Expression profiling by array.
Combined epigenetic therapy with FACT and BET inhibitors remodels chromatin and disrupts oncogenic transcription in Diffuse Midline Glioma [CUT&RUN]
GEO Series GSE272130. Homo sapiens. 29 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.