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1,337
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Dataset results
1,337 results for “Neuropathy”
Effects of Massage Therapy on Peripheral Neuropathy and Quality of Life
ClinicalTrials.gov study NCT05433246. IPD Sharing: NO. Countries: 0. Publications: 0.
The Effect of Oral Administration of Hesperidin and Diosmin in Reducing Paclitaxel-induced Peripheral Neuropathy in Breast Cancer Patients
ClinicalTrials.gov study NCT06811220. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Postoperative Peripheral Neuropathy After Laparoscopic Colorectal Surgery
ClinicalTrials.gov study NCT04343911. IPD Sharing: NO. Countries: 0. Publications: 0.
Safety Study of TAK-128 in Subjects With Diabetic Peripheral Neuropathy
ClinicalTrials.gov study NCT00756041. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Psychiatric Comorbidities in Patients With Painful Peripheral Neuropathy
ClinicalTrials.gov study NCT03275233. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
GEO Series GSE55802. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing; Expression profiling by array.
tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase
GEO Series GSE160584. Mus musculus. 2 samples. Type: Other.
Microbial-derived Hyodeoxycholic Acid Ameliorates Painful Diabetic Neuropathy by Modulating Dorsal Root Ganglion TLR4-Mediated Neuroinflammation Signaling Pathway
GEO Series GSE286026. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Neuregulin 1 type III reduces severity in a mouse model of Congenital Hypomyelination Neuropathy
GEO Series GSE101808. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
R-loop-induced DNA replication defects drive neuropathy in Koolen-de Vries syndrome
GEO Series GSE289456. Homo sapiens. 18 samples. Type: Other.
Mutations in tRNA synthetases impair translation and activate the integrated stress response in inherited peripheral neuropathie
GEO Series GSE145006. Mus musculus. 167 samples. Type: Expression profiling by high throughput sequencing.
Macrophage depletion blocks congenital SARM1-dependent neuropathy
GEO Series GSE210403. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Obstructed defecation – an enteric neuropathy? An exploratory study of patient samples
GEO Series GSE101968. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Down-stream effects in demyelinating neuropathies
GEO Series GSE7423. Homo sapiens. 12 samples. Type: Expression profiling by array.
Braf-mutant Schwann cells divert to a repair phenotype to induce congenital demyelinating neuropathy [SCP]
GEO Series GSE262048. Homo sapiens. 29 samples. Type: Expression profiling by high throughput sequencing.
Full transcriptome analysis reveals key regulatory networks and potential therapeutic targets of dorsal root ganglion in rats with painful diabetic peripheral neuropathy
GEO Series GSE305770. Rattus norvegicus. 10 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to: "Predictive factors of functional abilities in older patients with peripheral neuropathy"
<p>We provide the raw data used for the following article:</p> <p>Gialanella B, Prometti P, Comini L, Monguzzi V, Santoro R. <strong>Predictive factors of functional abilities in older patients with peripheral neuropathy.</strong> Aging Clin Exp Res. 2022 Jan;34(1):193-199. doi: 10.1007/s40520-021-01910-2. </p> <p>Abstract</p> <p><strong>Background and aims: </strong>Little is known about the outcome predictors in peripheral neuropathy (PN). This prospective observational study aimed to identify possible factors predicting the functional abilities in older patients with PN undergoing motor rehabilitation.</p> <p><strong>Methods: </strong>Data were collected in 80 PN patients, aged over 65 years, performing a standard inpatient motor rehabilitation program. The total Functional Independence Measure (FIM) score after rehabilitation, as well as efficiency and effectiveness in total-FIM, were the outcome measures. Backward multiple regression analyses identified the predictors of functional status.</p> <p><strong>Results: </strong>At the end of rehabilitation, total-FIM score was 102.66 ± 10.75, efficiency in total-FIM 0.64 ± 0.29 and effectiveness in total-FIM 48.81 ± 15.35%. Katz index at admission was a predictor of the final total-FIM score (beta 0.46, p < 0.001) and efficiency in total-FIM (beta - 0.38, p = 0.001). Conversely, age was a predictor of the final total-FIM score (beta - 0.31, p = 0.002) and effectiveness in total-FIM (beta - 0.49, p < 0.001). The R<sup>2</sup> values of the models were, respectively, 0.39, 0.15, and 0.24.</p> <p><strong>Discussion: </strong>In PN patients, functional impairment at admission and age are important predictors of functional abilities at the end of rehabilitation.</p> <p><strong>Conclusions: </strong>These findings suggest the need for more intensive rehabilitation in older, more disabled PN patients because they risk achieving lower functional levels with standard rehabilitation programs.</p>
datset related to article "PATHOLOGICAL MITOPHAGY DISRUPTS MITOCHONDRIAL HOMEOSTASIS IN LEBER'S HEREDITARY OPTIC NEUROPATHY"
<p><strong>Raw data from Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy – experiments of</strong> <strong>mito-autophagy present in specific regions of the idNeurons (soma and axon-dendrite (Ax-De) regions) </strong></p>
Dataset related to: "Determinants of improvement in functional abilities in peripheral neuropathy patients undergoing rehabilitation: the role of Berg Balance Scale items"
<p>We provide the raw data used for the following article:</p> <p>Gialanella B, Comini L, Prometti P. <strong>Determinants of improvement in functional abilities in peripheral neuropathy patients undergoing rehabilitation: the role of Berg Balance Scale items</strong>. Acta Neurol Belg. 2023 Feb;123(1):173-179. doi: 10.1007/s13760-021-01806-y. </p> <p>Abstract<br> Purpose This prospective observational cohort study aimed to verify whether single Berg Balance Scale (BBS) items were<br> important determinants of improvement in functional abilities in patients with peripheral neuropathy (PN).<br> Methods Data were collected in 75 older patients with PN performing a standard motor rehabilitation program. Backward<br> stepwise multiple regression analyses were performed to identify determinants of outcome measures. Gain in total and motor<br> Functional Independence Measure (FIM) and gain in motor-FIM areas were the outcome measures.<br> Results Among BBS items, at the end of rehabilitation, the score was higher in "sitting unsupported" (3.94 ± 0.22) and lower<br> in "standing on one foot" (1.18 ± 1.06). The gain was higher in "standing to sitting" (1.02 ± 0.67) and "standing unsupported"<br> (1.00 ± 1.00), and lower in "sitting unsupported" (0.22 ± 0.60) and "standing on one foot" (0.65 ± 0.77). "Standing unsupported"<br> was the only determinant of gain in motor-FIM (beta − 0.36, p = 0.002) and gain in self-care (beta − 0.37, p = 0.002).<br> The R2 value of the models was 0.13 and 0.14, respectively. No independent variable was a determinant of gain in total-FIM.<br> Conclusions The study shows that "unsupported standing" is an important determinant of results of ADL rehabilitation in<br> PN patients and indicates that ability to stand without support for a fairly long time is an essential requirement to achieve<br> with rehabilitation higher gain levels in functional abilities in PN patients.</p>
Dataset related to: "Effects of Motor Rehabilitation on Balance and Functional Activities in Elderly Patients with Peripheral Neuropathy and Recurrent Falls"
<p>We provide the raw data used for the following article:</p> <p><strong>Gialanella B, Comini L, Prometti P, Vanoglio F, Santoro R.</strong> Effects of Motor Rehabilitation on Balance and Functional Activities in Elderly Patients with Peripheral Neuropathy and Recurrent Falls. Life (Basel). 2023 Apr 20;13(4):1059. doi: 10.3390/life13041059. </p> <p><strong>Abstract:</strong> To date, little is known about the effects of motor rehabilitation in peripheral neuropathy (PN) patients with a history of recurrent falls (RFH). This study aimed to assess balance and the activities of daily living (ADLs) in elderly lower limb PN patients with and without RFH and to verify the effects of motor rehabilitation on balance and ADLs in these patients. We collected data from<br> 64 lower limb PN patients, who underwent a conventional motor rehabilitation program: 35 patients had a history of recurrent falls, and 29 did not. The Berg Balance Scale (BBS) and motor FIM, before and after rehabilitation, were the outcome measures. After rehabilitation, lower limb PN patients with RFH had significantly higher scores in BBS and motor FIM (p < 0.001, for both) than at entry. The final BBS score and effectiveness in the BBS score of lower limb PN patients with RFH were lower than those of patients without RFH (p < 0.05 and p = 0.009, respectively). The study shows that conventional motor rehabilitation improves both balance and ADLs in patients, but balance improvement is lower in those with RFH. Thus, motor rehabilitation can be a therapeutic option for<br> the management of these patients.</p> <p> </p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.