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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β-cell function [RNAseq]
GEO Series GSE182931. Rattus norvegicus; Mus musculus. 42 samples. Type: Expression profiling by high throughput sequencing.
The impact of hepatocyte specific Cyp51 disruption on development and sexual dimorphism in mice
GEO Series GSE78892. Mus musculus. 30 samples. Type: Expression profiling by array.
Differential gene expression in renal cortex resulting from SPAK gene disruption
GEO Series GSE60728. Mus musculus. 8 samples. Type: Expression profiling by array.
Targeted p63 isoform modulation corrects dominant mutations in AEC syndrome without disrupting epidermal homeostasis
GEO Series GSE298875. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
TCPOBOP-induced hepatomegaly & hepatocyte proliferation is attenuated by combined disruption of MET & EGFR signaling in mice
GEO Series GSE110695. Mus musculus. 8 samples. Type: Expression profiling by array.
Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders
GEO Series GSE294049. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to a variety of infectious agents [EBV B-cells]
GEO Series GSE164345. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
GEO Series GSE193184. Mus musculus. 92 samples. Type: Expression profiling by high throughput sequencing.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [CUT&RUN]
GEO Series GSE225994. Homo sapiens. 43 samples. Type: Other.
Genetic background and transient prenatal disruption of vitamin A signaling determine susceptibility to airway hyperresponsiveness in mice [RNA-Seq]
GEO Series GSE307576. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Latent HIV infection disrupts cell-intrinsic innate immunity [scRNA-seq]
GEO Series GSE176386. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
TNF-α Driven m6A Modification Disrupts MSCs Immune Regulatory Function by Regulating HDAC5-dependent Super Enhancer [RNA-seq]
GEO Series GSE284785. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Selective Targeting of PARP2 Inhibits Androgen Receptor Signaling and Prostate Cancer Growth Through Disruption of FOXA1 Function
GEO Series GSE114275. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells [Bulk RNA-seq 2]
GEO Series GSE296377. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Heterochromatin rewiring and domain disruption-mediated chromatin compaction during erythropoiesis [CUT&RUN]
GEO Series GSE183989. Homo sapiens. 28 samples. Type: Other.
TRAP-seq in 3D Angiogenesis Assays Reveals Distinct Biological Processes Associated with Early and Late Morphogenesis that are Disrupted with PIK3CA-H1047R
GEO Series GSE296693. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Targeting Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
GEO Series GSE87773. Homo sapiens. 9 samples. Type: Expression profiling by array.
K27M and K36M mutations on non canonical Histone 3.3 promote redistribution of antagonistic chromatin marks, disrupted development, and tumorigenesis
GEO Series GSE140979. Drosophila melanogaster. 68 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Developmental exposure to methyl ester sulfonate induces autism-like behavioral deficits in mice by dysregulation of the Notch/Hes signaling pathway disrupting neuronal differentiation
GEO Series GSE268561. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
R-2-hydroxyglutarate-mediated inhibition of KDM4A disrupts telomere integrity
GEO Series GSE283914. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.