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441
datasets available to search
ShareScore release 0.9.0
Dataset results
441 results for “Amyloidosis”
Exploration of Arrhythmia Burden in Cardiac Amyloidosis Using Implantable Loop Recorders
ClinicalTrials.gov study NCT04856267. IPD Sharing: UNDECIDED. Countries: 1. Publications: 13.
Epigallocatechingallate (EGCG) in Cardiac AL Amyloidosis
ClinicalTrials.gov study NCT01511263. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Prospective Identification of Cardiac Amyloidosis by Cardiac Magnetic Resonance Imaging
ClinicalTrials.gov study NCT02462213. IPD Sharing: Not stated. Countries: 1. Publications: 19.
A Study of PRX004 in Subjects With Amyloid Transthyretin (ATTR) Amyloidosis
ClinicalTrials.gov study NCT03336580. IPD Sharing: NO. Countries: 4. Publications: 1.
Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL Amyloidosis
ClinicalTrials.gov study NCT04392960. IPD Sharing: Not stated. Countries: 1. Publications: 10.
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
ClinicalTrials.gov study NCT06355934. IPD Sharing: YES. Countries: 10. Publications: 1.
EFICAC-TTR Trial: Exercise and Nutritional Supplementation in Transthyretin Cardiac Amyloidosis
ClinicalTrials.gov study NCT07343999. IPD Sharing: YES. Countries: 0. Publications: 5.
Lenalidomide, Dexamethasone and Cyclophosphamide in Amyloidosis (AL)
ClinicalTrials.gov study NCT00981708. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Minimal Residual Disease as a Possible Predictive Factor for Relapse in Patients With AL Amyloidosis
ClinicalTrials.gov study NCT02555969. IPD Sharing: Not stated. Countries: 1. Publications: 15.
Thalidomide/Dexamethasone Treatment And PET Evaluation In Organ Involvemenet of Cardiac Amyloidosis
ClinicalTrials.gov study NCT02966522. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Nutritional Counseling in Systemic Immunoglobulin Light-chain Amyloidosis
ClinicalTrials.gov study NCT02055534. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Recurrent AA Amyloidosis After Renal Transplantation
ClinicalTrials.gov study NCT02704065. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Phenotypic Manifestations of Hereditary ATTR Amyloidosis
ClinicalTrials.gov study NCT07124377. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Cardiac Amyloidosis Registry Study
ClinicalTrials.gov study NCT05174338. IPD Sharing: YES. Countries: 2. Publications: 0.
Application of High Resolution Optical Coherence Tomography in Skin Disease: Amyloidosis and Differential Diagnosis
ClinicalTrials.gov study NCT04068077. IPD Sharing: UNDECIDED. Countries: 1. Publications: 10.
Pomalidomide and Dexamethasone (PDex) in AL Amyloidosis
ClinicalTrials.gov study NCT01510613. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Amyloidosis Typing Using Mass Spectrometry-based Proteomics: a New Accurate Tool for Difficult Typing
ClinicalTrials.gov study NCT03984721. IPD Sharing: NO. Countries: 1. Publications: 2.
124I-p5+14 Injection Safety in Subjects With Systemic Amyloidosis
ClinicalTrials.gov study NCT03678259. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Neurofilament light chain (NfL) as a biomarker of hereditary transthyretin-mediated amyloidosis
<p>To identify changes in the proteome associated with onset and progression of ATTRv amyloidosis, we performed an observational, case-controlled study which compared proteomes of patients with ATTRv amyloidosis and healthy controls.</p> <p>Plasma levels of >1,000 proteins were measured in patients with ATTRv amyloidosis with polyneuropathy who received either placebo or patisiran in the APOLLO study and in healthy controls. The impact of patisiran on the time profile of each protein was determined by linear mixed model at 0, 9, and 18 months. Neurofilament light chain (NfL) was further assessed using an orthogonal quantitative approach.</p> <p>Levels of 66 proteins were significantly changed with patisiran vs placebo, with NfL change most significant (p < 10<sup>−20</sup>). Analysis of changes in protein levels demonstrated that the proteome of patisiran-treated patients trended toward healthy controls at 18 months. Healthy controls' NfL levels were 4-fold lower than in patients with ATTRv amyloidosis with polyneuropathy (16.3 vs 69.4 pg/mL, effect: −53.1 pg/mL, 95% CI [–60.5 to −45.9]). NfL levels at 18 months increased with placebo (99.5 vs 63.2 pg/mL, 36.3 pg/mL, [16.5–56.1]) and decreased with patisiran treatment (48.8 vs 72.1 pg/mL, −23.3 pg/mL, [–33.4 to −13.1]) from baseline. At 18 months, improvement in modified Neuropathy Impairment Score +7 following patisiran significantly correlated with reduced NfL (R = 0.43, [0.29–0.55]).</p> <p>Findings suggest NfL may serve as a biomarker of nerve damage and polyneuropathy in ATTRv amyloidosis, may enable earlier diagnosis of patients with ATTRv amyloidosis, and facilitate monitoring of disease progression.</p> <p>This study provides Class III evidence that NfL levels may enable earlier diagnosis of polyneuropathy in patients with ATTRv amyloidosis and facilitate monitoring of disease progression.</p>
Human Immune Globulin in Treating Patients With Primary Amyloidosis That is Causing Heart Dysfunction
ClinicalTrials.gov study NCT00547365. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.