Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
763
datasets available to search
ShareScore release 0.9.0
Dataset results
763 results for “Antioxidant”
Underlying data for In vivo assessment of the relationship between oral lichen planus and antioxidant status of vitamins A, C, and E in diabetic and hypertensive patients: An observational study
<p>Underlying data for In vivo assessment of the relationship between oral lichen planus and antioxidant status of vitamins A, C, and E in diabetic and hypertensive patients: An observational study</p>
STROBE checklist for: In vivo assessment of the relationship between oral lichen planus and antioxidant status of vitamins A, C, and E in diabetic and hypertensive patients: An observational study
<p>STROBE checklist for: In vivo assessment of the relationship between oral lichen planus and antioxidant status of vitamins A, C, and E in diabetic and hypertensive patients: An observational study</p>
Underlying data for Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients: an observational study
<p>Underlying data for Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients: an observational study</p>
Mammalian animal & human retinal organ culture as pre-clinical model to evaluate oxidative stress and antioxidant intraocular therapeutics
<p>Oxidative stress (OS) is involved in the pathogenesis of retinal neurodegenerative diseases like age-related macular degeneration (AMD) and diabetic retinopathy (DR) and an important target of therapeutic treatments. New therapeutics are tested in vivo despite limits in transferability and ethical concerns. Retina cultures using human tissue can deliver critical information and significantly reduce the number of animal experiments along with increased transferability. We cultured up to 32 retina samples derived from one eye, analyzed models’ quality, induced OS, and tested efficiency of antioxidative therapeutics. Bovine, porcine, rat, and human retinae were cultured in different experimental settings for 3-14 d. OS was induced by high-glucose or hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and treated by Scutellarin, pigment epithelium-derived factor (PEDF), and/or granulocyte macrophage-colony stimulating factor (GM-CSF). Tissue morphology, cell viability, inflammation, and glutathione level were determined. Retina samples showed only moderate necrosis (23.83±5.05 increased to 27.00±1.66 AU PI-staining over 14 d) after 14 days in culture. OS was successfully induced (reduced ATP content of 288.3±59.9 vs. 435.7±166.8 nM ATP in controls); antioxidants reduced OS-induced apoptosis (from 124.20±51.09 to 60.80±319.66 cells/image after Scutellarin-treatment). Enhanced mammalian animal and human retina cultures allow reliable, highly transferable research on OS-triggered age-related diseases and pre-clinical testing during drug development.</p>
Oxidation of a commercial antioxidant is driving increasing atmospheric abundance of a novel organophosphate ester: Implication for global regulation
<p>Data presented in the manuscript "Oxidation of a commercial antioxidant is driving increasing atmospheric abundance of a novel organophosphate ester: Implication for global regulation" by Liu et al. (2023).</p>
Fig. 2 in The antioxidant potential of retrochalcones isolated from liquorice root: A comparative DFT study
Fig. 2. Optimized geometries of the retrochalcones (1–6) in the gas phase (Mittal and Kakkar, 2021).
Fig. 1 in The antioxidant potential of retrochalcones isolated from liquorice root: A comparative DFT study
Fig. 1. The basic skeleton of a retrochalcone with atomic labeling and the list of substituents for the different retrochalcones (1–6).
Fig. 3 in The antioxidant potential of retrochalcones isolated from liquorice root: A comparative DFT study
Fig. 3. Probable routes associated with different antioxidant mechanisms of a retrochalcone molecule (Ch(OH)n).
Physicochemical characteristics and antioxidant activities of polysaccharides from red seaweeds
<p>Figure S1: <sup>1</sup>H NMR spectra of <em>Chondrus crispus </em>(CC), <em>Palmaria palmate </em>(PP)<em>, Ahnfeltiopsis devoniensis </em>(AD), <em>Sarcodiotheca gaudichaudii </em>(SG). <sup>1</sup>H-NMR spectroscopy showed the full spectrum: 0.0 to 9.0 ppm</p> <p>Figure S2: Spectroscopic analysis of <em>Chondrus crispus </em>extracts 2D HC-HSQC spectra A) CC1A, B) CC2B, C) AD3A, D) SG1A, E) PP2B;</p> <p>Figure S3:<em> </em>2D spectra (CC2A, CC2B) based on HSQCs with k- and i-standards carrageenans samples</p>
Fig. 8 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 8. The changes of the relative expression of WRI1 (A), BCCP2 (B), FAD2 (C), FAD3 (D) genes encoding after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves. Multivariate data analyses of gene expression analysis under investigation.
Fig. 5 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 5. The changes of the relative band intensity of different types of glutathione S-transferase activity isoenzymes (GST, A) and GST activity (B), and glutathione peroxidase activity (GPX, C) after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves.
Fig. 1 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 1. The average absorption per active reaction center (ABS/RC), the electron transport flux per active reaction center (ETo/RC), the flux of trapped exciton per active reaction center (TRo/RC), and the energy flow on the acceptor side of PSI ((Ro), The number of QA-reducing reaction centers per PSII antenna chlorophyll ((ΦPo/(1-ΦPo)), the efficiency with which a trapped exciton transfers an electron to the photosynthetic electron transfer chain ((ΨEo/(1-ΨEo)), the number of QA- reducing reaction centers per PSII antenna chlorophyll (γRC/(1-γRC)), the ratio of total dissipation to the number of active reaction centers (DIo/RC). The relative variable fluorescence intensity at J (VJ) and I step (VI), the performance index based on light absorption (PIABS), and the performance index (potential) for energy conservation from exciton to PSI and acceptor reduction (PItotal) were determined in A. thaliana leaves following treatment with rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦ C).
Fig. 7 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 7. The changes of monodehydroascorbate reductase activity (MDHAR, A), dehydroascorbate reductase activity (DHAR, B), ascorbate content (AsA, C), dehydroascorbate content (DHA, D), glutathione content (GSH, E), oxidized glutathione content (GSSG, F), AsA/DHA (G), GSH/GSSG (H) and GSH redox state (I) after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves.
Fig. 4 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 4. The changes of the relative band intensity of different types of peroxidase isoenzymes (POX, A) and POX activity (B), relative band intensity of different types of NADPH oxidase isoenzymes (NOX, C) and NOX activity (D) after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves.
Fig. 3 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 3. The changes of the relative band intensity of different types of superoxide dismutase isoenzymes (SOD, A) and SOD activity (B), the relative band intensity of different types of catalase isoenzymes (CAT, C) and CAT activity (D) after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves.
Fig. 2 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 2. The changes of hydrogen peroxide content (H O, A), lipid peroxidation (TBARS content, B), histochemical staining for O • accumulation (C), histochemical 2 2 2 staining for H2O2 determination (D), histochemical staining for plasma membrane integrity (E) and histochemical staining for lipid peroxidation (F) after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves.
Fig. 6 in Rosmarinic acid and hesperidin regulate gas exchange, chlorophyll fluorescence, antioxidant system and the fatty acid biosynthesis-related gene expression in Arabidopsis thaliana under heat stress
Fig. 6. The changes of the relative band intensity of different types of ascorbate glutathione isoenzymes (APX, A) and APX activity (B), and glutathione reductase activity (GR, C) after rosmarinic acid (RA, 100 μM) and/or hesperidin (HP, 100 μM) with/without heat stress (38 ◦C) in A. thaliana leaves.
Fig. 5 in Determination of phenolic profiles of Herniaria polygama and Herniaria incana fractions and their in vitro antioxidant and anti-inflammatory effects
Fig. 5. Antioxidant activity of the examined fractions isolated from Herniaria incana (HIhfr) and Herniaria polygama (HPfr) in blood plasma under the ONOO - induced oxidative stress in vitro. Protective effects of the examined Herniaria fractions were evaluated based on measurements of protein thiol groups (panel A), 3- nitrotyrosine (panel B), and the ferric reducing ability of plasma (panel C); n = 7, 8, and 9 for –SH groups, 3-nitrotyrosine, and FRAP assay, respectively.
Fig. 4 in Determination of phenolic profiles of Herniaria polygama and Herniaria incana fractions and their in vitro antioxidant and anti-inflammatory effects
Fig. 4. UHPLC – diode array detector (DAD) and charged aerosol detector (CAD) profiles of the Herniaria incana herb phenolic fraction.
Fig. 3 in Determination of phenolic profiles of Herniaria polygama and Herniaria incana fractions and their in vitro antioxidant and anti-inflammatory effects
Fig. 3. The chemical structures of isolated compounds (46, 52, 54, 55, and 56) from Herniaria incanaherb.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.