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6,699 results for “DEPRESSION”
Severe inbreeding depression is predicted by the "rare allele load" in Mimulus guttatus
<p>Most flowering plants are hermaphroditic and experience strong pressures to evolve self‐pollination (automatic selection, reproductive assurance). Inbreeding depression (ID) can oppose selection for selfing, but it remains unclear if ID is typically strong enough to maintain outcrossing. To measure the full cost of sustained inbreeding on fitness, and its genomic basis, we planted highly homozygous, fully genome‐sequenced inbred lines of yellow monkeyflower (<i>Mimulus guttatus)</i> in the field next to outbred plants from crosses between the same lines. The cost of full homozygosity is severe: 65% for survival, 86% for lifetime seed production. Accounting for the unmeasured effect of lethal and sterile mutations, we estimate that the average fitness of fully inbred genotypes is only 3–4% that of outbred competitors. The genome sequence data provides no indication of simple overdominance, but the number of rare alleles carried by a line, especially within rare allele clusters nonrandomly distributed across the genome, is a significant negative predictor of fitness measurements. These findings are consistent with a deleterious allele model for ID. High variance in rare allele load among lines and the genomic distribution of rare alleles both suggest that migration might be an important source of deleterious alleles to local populations.</p>
Data from: Effects of a titin mutation on force enhancement and force depression in mouse soleus muscles
The force produced by muscles varies with muscle length. Compared to isometric contractions at the same final length, force increases after lengthening, known as force enhancement, and decreases after shortening, known as force depression. The mechanisms of force enhancement remain unexplained by the sliding-filament and cross-bridge theories of muscle contraction. Although cross-bridge mechanisms have been proposed to account for force depression, so too have other mechanisms. In addition to cross bridges, titin has been suggested to contribute to both force enhancement and depression. Although titin is too compliant in passive muscles to contribute to active stiffness, recent evidence suggests that calcium activation increases titin stiffness. To test the hypothesis that titin plays a role in force enhancement and depression, we investigated muscle force in active and passive wild type and mdm soleus muscles after isovelocity stretching and shortening at three activation levels. Muscles from mdm mice (muscular dystrophy with myositis) have a predicted 83 amino acid deletion in the N2A region of titin and show no increase in stiffness when activated. We found that: 1) force enhancement and depression were reduced in mdm soleus compared to wild type muscles; 2) force enhancement increased with the amplitude of stretch across all activation levels in wild type and mdm muscles, while force depression increased with amplitude in wild type but not in mdm muscles; and 3) maximal shortening velocity of wild type and mdm muscles was similar, although active stress was reduced in mdm compared to wild type muscles. The results of this study suggest a role for titin in force enhancement and depression, which contribute importantly to regulation of muscle force during natural movements.
Inbreeding depression in a sexually selected weapon and the homologue in females
<p>Theory predicts that traits with heightened condition-dependence, such as sexually selected traits, should be affected by inbreeding to a greater degree than other traits. The presence of environmental stress may compound the negative consequences of inbreeding depression. In this study we examined inbreeding depression across multiple traits and whether it increased with a known form of environmental stress. We conducted our experiment using both sexes of the sexually dimorphic leaf-footed cactus bug, <em>Narnia femorata </em>(Hemiptera: Coreidae). Adult male cactus bugs have enlarged hind legs used as weapons in male-male contests; these traits, and their homologue in females, have been previously found to exhibit high condition-dependence. In this study, we employed small developmental group size as an environmental stress challenge. Nymph <em>N. femorata</em> aggregate throughout their juvenile stages, and previous work has shown the negative effects of small group size on survivorship and body size. We found evidence of inbreeding depression for survival and seven out of the eight morphological traits measured, in both sexes. Inbreeding depression was higher for the size of the male weapon and the female homolog. Additionally, small developmental group size negatively affected survival to adulthood. However, small group size did not magnify the effects of inbreeding on morphological traits. These findings support the hypothesis that traits with heightened condition-dependence exhibit higher levels of inbreeding depression.</p>
Residual force depression data
<p>Raw data used to create the results text and figures presented in the manuscript entitled "Residual force depression is not related to positive muscle fascicle work during submaximal voluntary dorsiflexion contractions in humans".</p>
Evaluation of Yoga Nidra In the Treatment of Depressive Disorder
<p>Abstract<br>The purpose of this study was to find out the effect of Yoga Nidra <br>interventions in improving depressive disorder. This study was conducted at <br>the Sir Sundar Lal Hospital, BHU, Varanasi. 10 patients were kept in <br>experimental group undergoing Yoga Nidra and 10 patients were kept in <br>control group who were taking the herbal medication. Each patient of <br>experimental group underwent 30 minutes practice of Yoga Nidra for the <br>total duration of 7 days. DASS- scale was used to assess the level of <br>depression in patients. The result has shown significant reduction of <br>depression score in the both of the groups. It was important to note that<br>the reduction of depression score was relatively more in experimental group <br>as compared to control group. Therefore the practice of Yoga Nidra has an <br>edge over the medication intake in tackling the depression</p> <p>Keywords: Yoga Nidra, Depression</p>
Data from: A randomized controlled safety and feasibility trial of floatation-REST in anxious and depressed individuals
<div> <div> <div> <div> <p>Background: Reduced Environmental Stimulation Therapy via floatation (floatation- REST) is a behavioral intervention designed to attenuate exteroceptive sensory input to the nervous system. Prior studies in anxious and depressed individuals demonstrated that single sessions of floatation-REST are safe, well-tolerated, and associated with an acute anxiolytic and antidepressant effect that persists for over 48 hours. However, the feasibility of using floatation-REST as a repeated intervention in anxious and depressed populations has not been well-investigated.</p> <p>Methods: In this single-blind safety and feasibility trial, 75 individuals with anxiety and depression were randomized to complete six sessions of floatation-REST in different formats: pool-REST (weekly 1-hour float sessions), pool-REST preferred (float sessions with flexibility of duration and frequency), or an active comparator (chair- REST; weekly 1-hour sessions in a Zero Gravity chair). Feasibility (primary outcome) was assessed via an 80% rate of adherence to the assigned intervention; tolerability via study dropout and duration/frequency of REST utilization; and safety via incidence of adverse events and ratings about the effects of REST.</p> <p>Results: Of 1,715 individuals initially screened, 75 participants were ultimately randomized. Six-session adherence was 85% for pool-REST (mean, M=5.1 sessions; standard deviation, SD=1.8), 89% for pool-REST preferred (M=5.3 sessions; SD=1.6), and 74% for chair-REST (M=4.4 sessions; SD=2.5). Dropout rates at the end of the intervention did not differ significantly between the treatment conditions. Mean session durations were 53.0 minutes (SD=12.3) for pool-REST, 75.4 minutes (SD=29.4) for pool-REST preferred, and 58.4 minutes (SD=4.3) for chair-REST. There were no serious adverse events associated with any intervention. Positive experiences were endorsed more commonly than negative ones and were also rated at higher levels of intensity.</p> <p>Conclusions: Six sessions of floatation-REST appear feasible, well-tolerated, and safe in anxious and depressed individuals. Floatation-REST induces positively-valenced experiences with few negative effects. Larger randomized controlled trials evaluating markers of clinical efficacy are warranted.</p> <p>Clinical Trial Registration Identifier: NCT03899090</p> </div> </div> </div> </div>
Human Placental Lactogen (Human Chorionic Somataomammotropin) and Oxytocin during Pregnancy: Individual Patterns and Association with Maternal-Fetal Attachment, Anxiety, and Depression
<p>Dataset from Human Placental Lactogen (Human Chorionic Somataomammotropin) and Oxytocin during Pregnancy: Individual Patterns and Association with Maternal-Fetal Attachment, Anxiety, and Depression</p>
Data from: An experimental paradigm for triggering a depressive syndrome
<p><span>Research investigating whether depression is an adaptation or a disorder has been hindered by the lack of an experimental paradigm that can test causal relationships. Moreover, studies attempting to induce the syndrome often fail to capture the suite of feelings, thoughts, and behaviours that characterize depression. An experimental paradigm for triggering depressive symptoms can improve our etiological understanding of the syndrome. The present study attempts to induce core symptoms of depression, particularly those related to rumination, in a healthy, non-clinical sample through a controlled social experiment. These symptoms are sad or depressed mood, anhedonia, feelings of worthlessness or guilt, and difficulty concentrating.</span><span> 134 undergraduate students were randomly assigned to either an Exclusion (EX) or Inclusion (IN) group. Participants in the Exclusion group were exposed to a modified Cyberball paradigm, designed to make them feel socially excluded, followed by a dual-interference task to </span><span>assess whether their exclusion interfered with their working memory. </span><span>Excluded participants: (1) self-reported a significant increase in sadness and decrease in happiness, but not anxiety or calmness; (2) scored significantly higher in four of five variables related to depressive rumination; and (3) performed significantly worse on a dual-interference task, suggesting an impaired ability to concentrate.</span></p>
Antenatal depression: Associations with birth and neonatal outcomes among women attending maternity care in Harare, Zimbabwe
<p>This is a dataset used to describe the results in a manuscript submitted to PLoS ONE</p>
Data from: Parasite-driven cascades or hydra effects: susceptibility and foraging depression shape parasite-host-resource interactions
<p>This contains data for the manuscript listed in the title.<br><br>We measured the foraging rates of individual zooplankton hosts, <em>Daphnia dentifera</em>, on phytoplankton resources, <em>Ankistrodesmus falcatus</em>, in the presence of fungal parasites of zooplankton, <em>Metschnikowia bicuspidata</em>. Some of these data are previously published (Genotypes12_foraging.csv by Strauss, Alexander T., et al. "Genotypic variation in parasite avoidance behaviour and other mechanistic, nonlinear components of transmission." <em>Proceedings of the Royal Society B</em> 286.1915 (2019): 20192164.) and some are published now for the first time (Genotype3_foraging.csv).<br><br>In addition, we present novel evidence from a mesocosm experiment (Mesocosm_data1.csv-Mesocosm_data20.csv) of populations of each genotype or each pair of genotypes with phytoplankton resources and fungal parasites present or absent; our last treatment was low or high nutrient supply for the phytoplankton. With data on infection prevalence, host density, and phytoplankton density, we show how host traits and nutrients control outcomes for prevalence, host density, and phytoplankton density.<br><br>These data may be reused with appropriate citation.</p>
Brain-Derived Neurotrophic Factor and extracellular vesicle-derived miRNAs in an Italian cohort of individuals with obesity: a key to explain the link between depression and atherothrombosis.
<p>This record contains raw data related to the article “Brain-Derived Neurotrophic Factor and Extracellular Vesicle-Derived miRNAs in an Italian Cohort of Individuals With Obesity: A Key to Explain the Link Between Depression and Atherothrombosis” </p> <p><em><strong>Abstract: </strong></em></p> <p><strong>Background</strong>: Obesity and depression are intertwined diseases often associated with an increased risk of cardiovascular (CV) complications. Brain-Derived Neurotrophic Factor (BDNF), altered in the brain both of subjects with depression and obesity, provides a potential link between depression and thrombosis. Since the relationship among peripheral BDNF, depression and obesity is not well-defined, the aim of the present report has been to address this issue taking advantage of the contribution played by extracellular vesicle (EV)-derived miRNAs. <strong>Research Process</strong>: Associations among circulating BDNF, depression and EVderived miRNAs related to atherothrombosis have been evaluated in a large Italian cohort of obese individuals (n = 743), characterized by the Beck Depression Inventory (BDI-II) score.<br> <strong>Results</strong>: BDI-II was negatively associated with BDNF levels without a significant impact of the rs6265 BDNF polymorphism; this association was modified by raised levels of IFN-g. BDNF levels were linked to an increase of 80 EV-derived miRNAs and a decrease of 59 miRNAs related to atherosclerosis and thrombosis. Network analysis identified at least 18 genes targeted by these miRNAs, 7 of which involved in depression and CV<br> risk. The observation of a possible link among BDNF, depression, and miRNAs related to atherothrombosis and depression in obesity is novel and may lead to a wider use of BDNF as a CV risk biomarker in this specific subject group.</p>
Datasets for Explainable Depression Detection on Twitter Aided by Metaphor Concept Mappings
<p><strong>Introduction</strong></p> <p>The datasets for training and evaluating our model for explainable depression detection on Twitter aided by metaphor concept mappings proposed in the following paper:</p> <p>Sooji, Han, Rui Mao, and Erik Cambria. "Hierarchical Attention Network for Explainable Depression Detection on Twitter Aided by Metaphor Concept Mappings." In Proceedings of the 29th International Conference on Computational Linguistics (COLING), 2022. in press</p> <p>Source code for our model is available at <a href="https://github.com/soojihan/HAN/blob/main/README.md">github.com/soojihan/HAN</a>.</p> <p>These datasets were generated using the dataset proposed in Shen et al., 2017. The original dataset is available at <a href="https://github.com/sunlightsgy/MDDL">github.com/sunlightsgy/MDDL</a>.</p> <p> </p> <p><strong>Description</strong></p> <p>There are three datasets. </p> <p><strong>1. mdl_HAN: </strong>This dataset contains tweets and metaphor concept mappings (MCMs) for 5,899 positive (i.e. depressed) and 4,469 negative users. Tweets in this dataset are extracted from the original MDDL dataset (Shen et al., 2017). MCMs were extracted using MetaPro (Mao et al., 2022). Please refer to our paper for more details.The name of each subfolder under the 'positive' and 'negative' subfolders is tweet userid. Each user's folder contains one or two json files:</p> <ul> <li>[userid].json: This json file contains tweet text objects, each of which is represented by [timestamp, tweet text].</li> <li>[userid]_cm.json: This json file contains MCMs, each of which is represented by [timestamp, MCM]</li> </ul> <p>Note that some users do not have MCMs. There's no [userid]_cm.json file in such users' folders.</p> <p><strong>2. imdl_HAN: </strong>This dataset has the same contents and structure as mdl_HAN except that explicit linguistic cues for depression (i.e., “I’m/I was/I am/I’ve been diagnosed depression” and words containing “depress”, “diagnos”, “anxiety”, “bipolar” and “disorder”) were removed from all tweets.</p> <p><strong>3. sampled_training_eval_data: </strong>This dataset contains 5 randomly sampled cross-validation sets. Each of the five set contains train.csv, test,csv and dev.csv. Each csv file contains user ids.</p> <p> </p> <p><strong>Remarks</strong></p> <p>If you use the datasets, please cite our paper:</p> <p>Sooji, Han, Rui Mao, and Erik Cambria. "Hierarchical Attention Network for Explainable Depression Detection on Twitter Aided by Metaphor Concept Mappings." In Proceedings of the 29th International Conference on Computational Linguistics (COLING), 2022. in press</p> <p> </p> <p><strong>Contact</strong></p> <p>If you have any questions about the datasets or source code for our model, please contact <a href="https://soojihan.github.io/">Sooji Han</a>.</p> <p> </p> <p><strong>References</strong></p> <p>Shen, Guangyao, Jia Jia, Liqiang Nie, Fuli Feng, Cunjun Zhang, Tianrui Hu, Tat-Seng Chua, and Wenwu Zhu. "Depression detection via harvesting social media: A multimodal dictionary learning solution." In <em>IJCAI</em>, pp. 3838-3844. 2017.</p> <p>Rui Mao, Xiao Li, Mengshi Ge, and Erik Cambria. 2022. MetaPro: A computational metaphor pro- cessing model for text pre-processing. Information Fusion, 86-87:30–43.</p> <p> </p>
Can age-related changes in parental care modulate inbreeding depression? A test using the burying beetle, Nicrophorus orbicollis
<p>Parental care has been shown to reduce the magnitude of inbreeding depression in some species with facultative care. However, parents often vary in the quality or amount of care they provide to their offspring and it is less clear whether this variation also impacts the magnitude of inbreeding depression. Here, we tested whether age related changes in parental care modulate the expression of inbreeding depression in the burying beetle, Nicrophorus orbicollis. Consistent with previous studies, we found that older parents produced larger broods of offspring than younger parents without sacrificing mean larval mass. Inbreeding depression was evident in several fitness-related traits: brood size at dispersal, the proportion of the brood that survived to eclosion, and mean age at death were all reduced in inbred broods compared to outbred broods. Surprisingly, inbred offspring were heavier at dispersal than outbred offspring. This was likely due to reduced sibling competition in inbred broods. Despite evidence for age related changes in parental investment and the existence of inbreeding depression, there was no evidence that an interaction between the two influenced any of the traits we measured. Our results suggest that age-related changes in parental care may be too slight to influence the expression of inbreeding depression.</p>
Associations of adverse maternal experiences and diabetes on postnatal maternal depression and child social-emotional outcomes in a South African community cohort
<p>Previous literature has identified associations between diabetes during pregnancy and postnatal maternal depression. Both maternal conditions are associated with adverse consequences on childhood development. Despite an especially high prevalence of diabetes during pregnancy and maternal postnatal depression in low- and middle-income countries, related research predominates in high-income countries. In a South African cohort with or without diabetes, we investigated associations between adverse maternal experiences with postnatal maternal depression and child social-emotional outcomes. South African mother-child dyads were recruited from the Bishop Lavis community in Cape Town. Participants consisted of 82 mother-child dyads (53 women had GDM or type 2 diabetes). At 14–20 months postpartum, maternal self-report questionnaires were administered to assess household socioeconomic status, food insecurity, maternal depressive symptoms (Edinburgh Postnatal Depression Scale (EPDS)), maternal trauma (Life Events Checklist), and child social-emotional development (Brief Infant Toddler Social Emotional Assessment, Ages and Stages Questionnaires: Social-Emotional, Second Edition). Lower educational attainment, lower household income, food insecurity, living without a partner, and having experienced physical assault were each associated with postnatal maternal depressive symptoms and clinical maternal depression (EPDS ≥ 13). Maternal postnatal depression, lower maternal educational attainment, lower household income, household food insecurity, and living in a single-parent household were each associated with child social-emotional problems. Stratified analyses revealed maternal experiences (education, income, food insecurity, trauma) were associated with postnatal maternal depressive symptoms and child social-emotional problems only among dyads with <em>in utero</em> exposure to diabetes. Women with pre-existing diabetes or gestational diabetes in LMIC settings should be screened for health-related social needs to reduce the prevalence of depression and to promote child social-emotional development.</p>
Patient-reported outcomes via electronic health record portal vs. telephone: process and retention data in a pilot trial of anxiety or depression symptoms in epilepsy
<p>Objective: To close gaps between research and clinical practice, tools are needed for efficient pragmatic trial recruitment and patient-reported outcome(PROM) collection. The objective was to assess feasibility and process measures for patient-reported outcome collection in a randomized trial comparing electronic health record(EHR) patient portal questionnaires to telephone interview among adults with epilepsy and anxiety or depression symptoms.</p> <p>Results: Participants were 60% women, 77% White/non-Hispanic, with mean age 42.5 years. Among 15 individuals randomized to EHR portal, 10(67%, CI 41.7-84.8%) met the 6-month retention endpoint, versus 100%(CI 79.6-100%) in the telephone group(p=0.04). EHR outcome collection at 6 months required 11.8 minutes less research staff time per participant than telephone (5.9, CI 3.3-7.7 vs. 17.7, CI 14.1-20.2). Subsequent telephone contact after unsuccessful EHR attempts enabled near complete data collection and still saved staff time.</p> <p>Discussion: Data from this randomized pilot study of pragmatic outcome collection methods for patients with anxiety or depression symptoms in epilepsy includes baseline participant characteristics, recruitment flow resulting from a novel EHR-based, care-embedded recruitment process, and data on retention along with various process measures at 6-months.</p>
Machar Stones - natural depressions
Situated deep in the Carron Valley forest are two adjacent standing stones: one upright, the other semi-recumbent. Cups markings have been reported on the latter. However, on visiting these (15/2/19) it was apparent that any markings are natural. The rocks are a conglomerate with somewhat angular, gravel sized stones in a rather coarse sandstone matrix. There are depressions on the semi-recumbent stone but these are quite apparently the residual impressions of larger stones that have weathered out of the matrix. SCRAP ID 1721 LOCATION OS Grid Ref: NS 65707 83932 Source: Objaverse 1.0 / Sketchfab
Data for "Depressed-cladding thulium-doped fiber for applications below 1800 nm"
<p>Dataset includes simulation results as well as confirming experimental data for depressed-cladding thulium-doped fiber presented in the graphs.</p>
FIGURE 9 in Deciduous dentition and dental eruption sequence of Bothriogenys fraasi (Anthracotheriidae, Artiodactyla) from the Fayum Depression, Egypt
FIGURE 9. Comparison of the different stages (I-V) of the eruption sequence of Bothriogenys fraasi.
Data from: Heterosis is common and inbreeding depression absent in natural populations of Arabidopsis thaliana
The importance of genetic drift in shaping patterns of adaptive genetic variation in nature is poorly known. Genetic drift should drive partially recessive deleterious mutations to high frequency, and inter‐population crosses may therefore exhibit heterosis (increased fitness relative to intra‐population crosses). Low genetic diversity and greater genetic distance between populations should increase the magnitude of heterosis. Moreover, drift and selection should remove strongly deleterious recessive alleles from individual populations, resulting in reduced inbreeding depression. To estimate heterosis, we crossed 90 independent line pairs of Arabidopsis thaliana from 15 pairs of natural populations sampled across Fennoscandia, and crossed an additional 41 line pairs from a subset of 4 of these populations to estimate inbreeding depression. We measured lifetime fitness of crosses relative to parents in a large outdoor common garden (8448 plants in total) in central Sweden. To examine the effects of genetic diversity and genetic distance on heterosis, we genotyped parental lines for 869 SNPs. Overall, genetic variation within populations was low (median expected heterozygosity = 0.02), and genetic differentiation was high (median FST = 0.82). Crosses between 10 of 15 population pairs exhibited significant heterosis, with magnitudes of heterosis as high as 117%. We found no significant inbreeding depression, suggesting that the observed heterosis is due to fixation of mildly deleterious alleles within populations. Widespread and substantial heterosis indicates an important role for drift in shaping genetic variation, but there was no significant relationship between fitness of crosses relative to parents and genetic diversity or genetic distance between populations.
PSYCHE-D: predicting change in depression severity using person-generated health data (DATASET)
<p>This dataset is made available under <a href="https://creativecommons.org/licenses/by-nc/4.0/">Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)</a>. See LICENSE.pdf for details.</p> <p><strong>Dataset description</strong></p> <p>Parquet file, with:</p> <ul> <li>35694 rows</li> <li>154 columns</li> </ul> <p>The file is indexed on [<em>participant</em>]_[<em>month</em>], such that 34_12 means month 12 from participant 34. All participant IDs have been replaced with randomly generated integers and the conversion table deleted.</p> <p>Column names and explanations are included as a separate tab-delimited file. Detailed descriptions of feature engineering are available from the linked publications.</p> <p>File contains aggregated, derived feature matrix describing person-generated health data (PGHD) captured as part of the DiSCover Project (<a href="https://clinicaltrials.gov/ct2/show/NCT03421223">https://clinicaltrials.gov/ct2/show/NCT03421223</a>). This matrix focuses on individual changes in depression status over time, as measured by PHQ-9.</p> <p>The DiSCover Project is a 1-year long longitudinal study consisting of 10,036 individuals in the United States, who wore consumer-grade wearable devices throughout the study and completed monthly surveys about their mental health and/or lifestyle changes, between January 2018 and January 2020.</p> <p>The data subset used in this work comprises the following:</p> <ul> <li>Wearable PGHD: step and sleep data from the participants’ consumer-grade wearable devices (Fitbit) worn throughout the study</li> <li>Screener survey: prior to the study, participants self-reported socio-demographic information, as well as comorbidities</li> <li>Lifestyle and medication changes (LMC) survey: every month, participants were requested to complete a brief survey reporting changes in their lifestyle and medication over the past month</li> <li>Patient Health Questionnaire (PHQ-9) score: every 3 months, participants were requested to complete the PHQ-9, a 9-item questionnaire that has proven to be reliable and valid to measure depression severity</li> </ul> <p>From these input sources we define a range of input features, both static (defined once, remain constant for all samples from a given participant throughout the study, e.g. demographic features) and dynamic (varying with time for a given participant, e.g. behavioral features derived from consumer-grade wearables).</p> <p>The dataset contains a total of 35,694 rows for each month of data collection from the participants. We can generate 3-month long, non-overlapping, independent samples to capture changes in depression status over time with PGHD. We use the notation ‘SM0’ (sample month 0), ‘SM1’, ‘SM2’ and ‘SM3’ to refer to relative time points within each sample. Each 3-month sample consists of: PHQ-9 survey responses at SM0 and SM3, one set of screener survey responses, LMC survey responses at SM3 (as well as SM1, SM2, if available), and wearable PGHD for SM3 (and SM1, SM2, if available). The wearable PGHD includes data collected from 8 to 14 days prior to the PHQ-9 label generation date at SM3. Doing this generates a total of 10,866 samples from 4,036 unique participants.</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.