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ShareScore release 0.9.0
Dataset results
284 results for “Muscle disease”
Rehabilitative Impact of Exercise Training on Human Skeletal Muscle Transcriptional Programs in Parkinson’s Disease
GEO Series GSE140089. Homo sapiens. 41 samples. Type: Expression profiling by high throughput sequencing.
Single cell compendium of the muscle microenvironment in peripheral artery disease reveals capillary endothelial heterogeneity and activation of resident macrophages
GEO Series GSE287300. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profile of three-dimensional tissue-engineered human skeletal muscle model of Pompe disease and recombinant protein therapy
GEO Series GSE159062. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies
GEO Series GSE111163. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
Data from: Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne
Urine is increasingly being considered as a source of biomarker development in Duchenne Muscular Dystrophy (DMD), a severe, life-limiting disorder that affects approximately 1 in 4500 boys. In this study, we considered the mdx mice—a murine model of DMD—to discover biomarkers of disease, as well as pharmacodynamic biomarkers responsive to prednisolone, a corticosteroid commonly used to treat DMD. Longitudinal urine samples were analyzed from male age-matched mdx and wild-type mice randomized to prednisolone or vehicle control via liquid chromatography tandem mass spectrometry. A large number of metabolites (869 out of 6,334) were found to be significantly different between mdx and wild-type mice at baseline (Bonferroni-adjusted p-value < 0.05), thus being associated with disease status. These included a metabolite with m/z = 357 and creatine, which were also reported in a previous human study looking at serum. Novel observations in this study included peaks identified as biliverdin and hypusine. These four metabolites were significantly higher at baseline in the urine of mdx mice compared to wild-type, and significantly changed their levels over time after baseline. Creatine and biliverdin levels were also different between treated and control groups, but for creatine this may have been driven by an imbalance at baseline. In conclusion, our study reports a number of biomarkers, both known and novel, which may be related to either the mechanisms of muscle injury in DMD or prednisolone treatment.
Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease
ClinicalTrials.gov study NCT07292311. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov study NCT02877641. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Home-based Cardiovascular Rehabilitation in Young Patients With Congenital Heart Disease: the "Muscle Your Heart" Program
ClinicalTrials.gov study NCT07115589. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Inspiratory Muscle Activation Pattern Analysis in Assisting Precision in Inspiratory Muscle Training in Patients With Chronic Respiratory Disease
ClinicalTrials.gov study NCT03880630. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Disease Severity, Mortality Risk, and Muscle Function in Intensive Care Unit Patients
ClinicalTrials.gov study NCT07124442. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Transcriptomic Analysis to Put an End to Misdiagnosis in Patients With Rare Muscle Diseases
ClinicalTrials.gov study NCT06833489. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Vitamin D Supplementation on Muscle Function Among Grave's Disease Patients
ClinicalTrials.gov study NCT06451016. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of a Respiratory Muscle Warm-up Prior to Exercise in Patients With Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov study NCT02532075. IPD Sharing: NO. Countries: 1. Publications: 0.
Lingual Muscle Training in Late-Onset Pompe Disease (LOPD)
ClinicalTrials.gov study NCT03255213. IPD Sharing: NO. Countries: 1. Publications: 0.
Functional Inspiratory Muscle Training in Chronic Kidney Disease
ClinicalTrials.gov study NCT04958759. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Developing an Effective Intervention to Address Post-Corona-Virus-Disease-2019 Balance Disorders, Weakness and Muscle Fatigue in Individuals Aged 65+
ClinicalTrials.gov study NCT05934279. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effect of Exercise Training on Skeletal Muscle Metabolism in Peripheral Artery Disease (PAD)
ClinicalTrials.gov study NCT01231360. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Inspiratory Muscle Training on Parkinson's Disease
ClinicalTrials.gov study NCT06912997. IPD Sharing: NO. Countries: 1. Publications: 0.
The Optimal Protein Intake to Enhance Muscle Mass in Elderly Patients With Pre-dialysis Chronic Kidney Disease
ClinicalTrials.gov study NCT07102667. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Skeletal Muscle Function in Interstitial Lung Disease
ClinicalTrials.gov study NCT03800017. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.