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299 results for “Risk stratification”
ChatGPT Provides Inconsistent Risk-Stratification of Patients With Atraumatic Chest Pain - Dataset
<p>Dataset for analysis of the ability of ChatGPT to risk-stratify patients with atraumatic chest pain</p>
Risk stratification and prognostic value of basic coagulation parameters among COVID-19 patients
<p class="MsoNormal"><strong><span>Background</span></strong><span>:<strong> </strong></span><span>COVID-19 is a viral disease caused by a new strain of coronaviru<span>s</span><span><span>.</span></span> Currently, prognosis and risk stratification of COVID-19 patients is done by the disease's clinical presentation. Therefore, identifying laboratory biomarkers for disease prognosis and risk stratification of COVID-19 patients is critical for prompt treatment. Therefore, the main objective of this study was to </span><span>assess the risk stratification and prognostic value of basic coagulation parameters and factors associated with disease severity among COVID-19 patients, Northwest Ethiopia.</span></p> <p class="MsoNormal"><strong><span>Methods</span></strong><span>:<strong> </strong></span><span>A follow-up study was conducted among conveniently recruited COVID-19 patients attended from March to June 2021. Socio-demographic and clinical data were collected using a structured questionnaire and checklist, respectively. </span><span>Prothrombin time (PT) and activated partial thromboplastin time (APTT)</span><span> were analyzed by the HUMACLOT DUE PLUS<sup>®</sup> machine. Descriptive statistics were used to summarize the socio-demographic and clinical characteristics of study participants. Kruskal Wallis tests were used to compare the difference between parametric and non-parametric continuous variables, respectively. The area under the receiver operating characteristic curve (AUC) was used to evaluate the value of PT and APTT in the risk stratification and disease prognosis of COVID-19 patients. </span><span>Ordinal</span><span> logistic regression<span> was used to identify the factors associated with disease severity and prognosis</span>. </span><span>A P-value < 0.05 was defined as statistically significant for all results.</span></p> <p class="MsoNormal"><strong><span>Result</span></strong><span>:<strong> </strong></span><span>Baseline PT at a cut-off value <span class="red-underline">≥ </span>16.25 seconds differentiated severe COVID-19 patients from mild and moderate patients (AUC: 0.89, 95% CI: 0.83</span><span><span>–</span>0.95). PT also differentiated mild COVID-19 patients from moderate and severe patients at a cut-off value <span class="red-underline">≤ </span>15.35 seconds (AUC: 0.90, 95% CI: 0.84–0.96). Moreover, alcohol drinkers were 3.52 times more likely chance of having severe disease than non-drinkers (95% CI: 1.41–8.81). A one-year increment in age also increased the odds of disease severity by 6% (95% CI: 3</span><span><span>–</span>9%). An increment of </span><span>≥ 0.65 </span><span>seconds from the baseline<span> </span>PT predicted poor prognosis (AUC:</span><span> 0.93, 0.87–0.99)</span><span>. </span></p> <p class="MsoNormal"><strong><span>Conclusions and recommendations</span></strong><span>:</span><strong><span> </span></strong><span>Prolonged baseline PT was observed in severe COVID-19 patients. <span>Prolonged baseline PT was also predicted to worsen prognosis. An increase from the baseline PT was associated with worsen prognosis. Therefore, </span></span><span>PT can be used as a risk stratification and prognostic marker in COVID-19 patients.</span></p>
The added value of right ventricular function normalized for afterload to improve risk stratification of patients with pulmonary arterial hypertension
<p>Dataset of the paper</p>
Avascular Retina Area Modeling for Stratification Risk in Retinopathy of Prematurity
<p>Source data</p>
Mean Platelet Volume and Its Relation to Risk Stratification of Myelodysplastic Syndromes
ClinicalTrials.gov study NCT05204953. IPD Sharing: Not stated. Countries: 0. Publications: 6.
Study of Early Stage Endometrial Cancer Based on Molecular Classification and Traditional Risk Stratification to Guide Adjuvant Radiotherapy Decisions
ClinicalTrials.gov study NCT05524389. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
ClinicalTrials.gov study NCT06023641. IPD Sharing: YES. Countries: 1. Publications: 0.
Phase II Treatment Stratification Trial Using Neck Dissection-Driven Selection to Improve Quality of Life for Low Risk Patients With HPV+ Oropharyngeal Squamous Cell Cancer
ClinicalTrials.gov study NCT02784288. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Risk Stratification-directed Therapy for AML With t(8;21) /AML1-ETO+
ClinicalTrials.gov study NCT02936089. IPD Sharing: YES. Countries: 0. Publications: 1.
Multifactorial Risk Stratification in Stroke Patients With Cardiac Disease
ClinicalTrials.gov study NCT04352790. IPD Sharing: UNDECIDED. Countries: 0. Publications: 2.
Implantable Cardioverter Defibrillators - Improving Risk Stratification
ClinicalTrials.gov study NCT01944514. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Risk Stratifications for Patients With Palpitations
ClinicalTrials.gov study NCT06103305. IPD Sharing: Not stated. Countries: 0. Publications: 15.
Risk Stratification and Early Alerting Regarding COVID-19 Hospitalization
ClinicalTrials.gov study NCT04709068. IPD Sharing: NO. Countries: 1. Publications: 0.
Biomarkers and Risk Scores for Risk Stratification of Unstable Angina
ClinicalTrials.gov study NCT03628586. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
The Role of Endothelial Function Test in Risk Stratification for Early and Late Complications After Pulmonary Embolism
ClinicalTrials.gov study NCT03149471. IPD Sharing: NO. Countries: 0. Publications: 12.
Deep Learning With MRI-based Multimodal-data Fusion Enhanced Postoperative Risk Stratification of Breast Cancer
ClinicalTrials.gov study NCT06546072. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Body Fat Index for Obstetric Risk Stratification
ClinicalTrials.gov study NCT05533996. IPD Sharing: NO. Countries: 0. Publications: 14.
Gene Expression Profiles and ctDNA for Risk Stratification in Patients With Melanoma
ClinicalTrials.gov study NCT06566404. IPD Sharing: Not stated. Countries: 0. Publications: 7.
The Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal
ClinicalTrials.gov study NCT03702270. IPD Sharing: NO. Countries: 1. Publications: 0.
Risk stratification and prognostic value of basic coagulation parameters among COVID-19 patients
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
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OpenNeuro
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