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310 results for “aortic stenosis”
Data files for the manuscript Oxidized phospholipids associated with lipoprotein(a) contribute to hypofibrinolysis in severe aortic stenosis
Open the record for dataset details and reuse information.
Outcomes of Transcatheter Aortic Valve Implantation in Management of Severe Symptomatic Aortic Stenosis
ClinicalTrials.gov study NCT03633383. IPD Sharing: Not stated. Countries: 0. Publications: 6.
Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Study
ClinicalTrials.gov study NCT01272388. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Involvement of the Gut Microbiota in Calcified Aortic Stenosis
ClinicalTrials.gov study NCT06021535. IPD Sharing: NO. Countries: 0. Publications: 6.
Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis
ClinicalTrials.gov study NCT01905852. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS)
ClinicalTrials.gov study NCT03483051. IPD Sharing: NO. Countries: 1. Publications: 0.
The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis
ClinicalTrials.gov study NCT03471065. IPD Sharing: NO. Countries: 2. Publications: 0.
COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis.
ClinicalTrials.gov study NCT04420325. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Impact of a Patient Decision Aid for Treatment of Aortic Stenosis
ClinicalTrials.gov study NCT04103931. IPD Sharing: YES. Countries: 1. Publications: 0.
Rapid Non-invasive Detection of Aortic Stenosis
ClinicalTrials.gov study NCT04024566. IPD Sharing: NO. Countries: 1. Publications: 0.
ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
ClinicalTrials.gov study NCT03517436. IPD Sharing: NO. Countries: 1. Publications: 0.
Inflammation and Thrombosis in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (TAVR)
ClinicalTrials.gov study NCT02486367. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis
ClinicalTrials.gov study NCT03442400. IPD Sharing: NO. Countries: 1. Publications: 0.
Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study
ClinicalTrials.gov study NCT01275339. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effective Management of Calcific Aortic Stenosis in the Elderly
ClinicalTrials.gov study NCT03343314. IPD Sharing: NO. Countries: 0. Publications: 15.
Mechanisms of Fibrotic Aortic Valve Stenosis
GEO Series GSE71534. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Aortic Valve Tissue: Stenosis vs. Sclerosis
GEO Series GSE138531. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to the article "Isolated Valve Amyloid Deposition in Aortic Stenosis: Potential Clinical and Pathophysiological Relevance"
<p>This record contains raw data related to the article "Isolated Valve Amyloid Deposition in Aortic Stenosis: Potential Clinical and Pathophysiological Relevance"</p> <p>Abstract: Amyloid deposition within stenotic aortic valves (AVs) also appears frequent in the absence of cardiac amyloidosis, but its clinical and pathophysiological relevance has not been investigated. We will elucidate the rate of isolated AV amyloid deposition and its potential clinical and pathophysiological significance in aortic stenosis (AS). In 130 patients without systemic and/or cardiac amyloidosis, we collected the explanted AVs during cardiac surgery: 57 patients with calcific AS<br>and 73 patients with AV insufficiency (41 with AV sclerosis and 32 without, who were used as controls). Amyloid deposition was found in 21 AS valves (37%), 4 sclerotic AVs (10%), and none of the controls. Patients with and without isolated AV amyloid deposition had similar clinical and echocardiographic characteristics and survival rates. Isolated AV amyloid deposition was associated with higher degrees of AV fibrosis (p = 0.0082) and calcification (p < 0.0001). Immunohistochemistry analysis suggested serum amyloid A1 (SAA1), in addition to transthyretin (TTR), as the protein possibly involved in AV amyloid deposition. Circulating SAA1 levels were within the normal range<br>in all groups, and no difference was observed in AS patients with and without AV amyloid deposition. In vitro, AV interstitial cells (VICs) were stimulated with interleukin (IL)-1β which induced increased SAA1-mRNA both in the control VICs (+6.4 ± 0.5, p = 0.02) and the AS VICs (+7.6 ± 0.5, p = 0.008). In conclusion, isolated AV amyloid deposition is frequent in the context of AS, but it does not appear to have potential clinical relevance. Conversely, amyloid deposition within AV leaflets, probably promoted by local inflammation, could play a role in AS pathophysiology.</p>
Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis
ClinicalTrials.gov study NCT04613193. IPD Sharing: NO. Countries: 1. Publications: 0.
Smartphone Based Digital Screening for Aortic Valve Stenosis
ClinicalTrials.gov study NCT07284550. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.