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141
datasets available to search
ShareScore release 0.9.0
Dataset results
141 results for “cardiac tissue”
Differential transcriptional responses to cardiomyocyte-specific Notch activation in right versus left atria of murine cardiac tissue
GEO Series GSE138253. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Leptin-Activated Crosstalk Among Brain, Brown Adipose Tissue, and Heart Drives Cardiac Protection After Ischemia-Reperfusion Injury [miRNA-seq]
GEO Series GSE315349. Rattus norvegicus. 16 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Leptin-Activated Crosstalk Among Brain, Brown Adipose Tissue, and Heart Drives Cardiac Protection After Ischemia-Reperfusion Injury [RNA-seq]
GEO Series GSE315348. Rattus norvegicus. 24 samples. Type: Expression profiling by high throughput sequencing.
Cytomegalovirus latency exacerbates cardiac inflammation and tissue remodeling after myocardial infarction
GEO Series GSE309570. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Connexin 43 Suppression Enhances Contractile Force in Human iPSC-derived Cardiac Tissues
GEO Series GSE304132. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Gene expression of cardiac tissues in dietary obese mice administered with a dipeptidyl peptidase-4 inhibitor
GEO Series GSE98226. Mus musculus; Mus sp.. 9 samples. Type: Expression profiling by array.
Transcriptome of cardiac tissue from WT mice, cardiac macrophages depleted mice, and mice deficient for Mertk and LxR
GEO Series GSE106295. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Untreated Rat Cardiac Ventricular tissue Age
GEO Series GSE272911. Rattus rattus. 6 samples. Type: Expression profiling by high throughput sequencing.
Gene Expression Profiles in Engineered Cardiac Tissues Respond to Mechanical Loading and Inhibition of Tyrosine Kinase
GEO Series GSE48342. Rattus norvegicus. 22 samples. Type: Expression profiling by array.
DNA methylation profiles of isolated embryonic and adult cardiomyocytes, cardiac fibroblasts, tissue and stem cells.
GEO Series GSE61249. Mus musculus. 10 samples. Type: Methylation profiling by high throughput sequencing.
Effect of depletion of vacuolar protein sorting 13 homolog c (Vps13c) in heart tissue from ventricles of wild-type (WT) and cardiac-specific knockout (Vps13c-cKO) mice.
GEO Series GSE307260. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing analysis of mouse cardiac endothelial cells in myocardial infarction tissues
GEO Series GSE163772. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Single Cell Transcriptomic Profiling of Cardiac Tissues and Surrounding Tissues During Early Cardiac Development
GEO Series GSE205950. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to the article "Presence of SARS-CoV-2 nucleoprotein in cardiac tissues of donors negative to COVID-19 molecular tests"
<p>This record contains raw data related to the article “Presence of SARS-CoV-2 nucleoprotein in cardiac tissues of donors negative to COVID-19 molecular tests”</p> <p> </p> <p>Abstract</p> <p><strong>Background:</strong> COVID-19 outbreak caused detrimental effects on essential medical services as organ and tissue donation. Lombardy, one of the most active Italian region in organ/tissue procurement, has been strongly affected by the COVID-19 pandemic. To date, data concerning the risk of SARS-CoV-2 transmission after tissue transplantation are controversial. Here we aim to evaluate the presence/absence of SARS-CoV-2 in different cardiac tissues eligible for transplantation obtained from Lombard donors.</p> <p><strong>Methods and Results:</strong> We used cardiovascular tissues from eight donors potentially suitable for pulmonary valve transplantation. All donor subjects involved in the study were negative for the SARS-CoV-2 RNA molecular tests (qRT-PCR and chip-based digital PCR) in NPS and/or BAL. None of the 8 donors included in this study revealed viral genome SARS-CoV-2 presence. However, the evaluation of protein content of pulmonary vein wall (PVW) tissue revealed in all donors variable levels of SARS-CoV-2 nucleoprotein signal.</p> <p><strong>Conclusion:</strong> Our study demonstrated for the first time, to the best of our knowledge, that, viral nucleoprotein but not viral RNA was present in the tissue bank examined specimens, suggesting caution and in-depth investigations on implantable tissue specimens collected during COVID-19 pandemic period.</p>
MicroRNA-122-mediated liver detargeting enhances the tissue specificity of cardiac genome editing
GEO Series GSE245091. Mus musculus. 138 samples. Type: Other.
NGS-based miRNome profile in cardiac muscle tissue of congenital heart disease patients
GEO Series GSE185565. Homo sapiens. 10 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptome analysis from human epicardial adipose tissue biopsies analyzed according to postoperative atrial fibrillation occurrence after cardiac surgery
GEO Series GSE143924. Homo sapiens. 30 samples. Type: Expression profiling by array.
Pharmacological inhibition of the MAPK pathway ameliorates RIT1M90I-driven cardiac tissue hypertrophy.
GEO Series GSE207187. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "A chromEM-staining protocol optimized for cardiac tissue"
<p>This record contains raw data related to article "A chromEM-staining protocol optimized for cardiac tissue"</p><p>Three-dimensional (3D) chromatin organization has a key role in defining the transcription program of cells during development. Its alteration is the cause of gene expression changes responsible for several diseases. Thus, we need new tools to study this aspect of gene expression regulation. To this end, ChromEM was recently developed: this is an electron-microscopy staining technique that selectively marks nuclear DNA without altering its structure and, thus, allows better visualization of 3D chromatin conformation. However, despite increasingly frequent application of this staining technique on cells, it has not yet been applied to visualize chromatin ultrastructure in tissues. Here, we provide a protocol to carry out ChromEM on myocardial tissue harvested from the left ventricles of C57BL/6J mice and use this in combination with transmission electron microscopy (TEM) to measure some morphological parameters of peripheral heterochromatin in cardiomyocytes. This protocol could also be used, in combination with electron tomography, to study 3D chromatin organization in cardiomyocytes in different aspects of heart pathobiology (e.g., heart development, cardiac aging, and heart failure) as well as help to set-up ChromEM in other tissues. </p>
Transcriptional characterization of cardiac tissue of rat pups with pulmonary banding
GEO Series GSE143745. Rattus norvegicus. 20 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.