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131
datasets available to search
ShareScore release 0.9.0
Dataset results
131 results for “clinical cases”
Evaluation of Intracanal Reinforcement with Short Composite Post in Upper Primary Incisors with Severly Carious Teeth As in Early Childhood Caries Cases Using Randomized Clinical Trial
ClinicalTrials.gov study NCT06740643. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Clinical Effectiveness of the MultiCentre Pain Monitor to Guide and Personalize Psychological Treatments: A Single Case Design
ClinicalTrials.gov study NCT05098288. IPD Sharing: NO. Countries: 0. Publications: 0.
Short Clinical Outcome of Microscope Assisted Discectomy: Results of 90 Cases in Iraq
ClinicalTrials.gov study NCT04109781. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Lynparza Ovarian Cancer Clinical Experience Investigation (All Case Investigation)
ClinicalTrials.gov study NCT03505307. IPD Sharing: YES. Countries: 0. Publications: 0.
Clinical and Microbiological Relationships Between Periodontitis and Abdominal Aorta Aneurism: an Case Control Study
ClinicalTrials.gov study NCT03767023. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Active Case Finding of Clinical Hand Foot Mouth Disease in Children Aged 6 Months Old to 18 Years Old in Indonesia
ClinicalTrials.gov study NCT06251219. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
This Hospital-based Observational Study Employed a Study Will be Conducted in Sohag University Hospital Clinics Aiming to Ensure Cases Presented With Psychosis in Two Phases to Differentiate Into Two
ClinicalTrials.gov study NCT07184710. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Laboratory Study Using Samples From Patients With Non-Small Cell Lung Cancer Treated on Clinical Trial CASE-2507
ClinicalTrials.gov study NCT00907699. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Drug-interaction annotations over full text articles reporting on clinical studies reports or case reports
<p>Drug interaction annotations over full text reports. These annotations were done as part of the National Library of Medicine funded research project "Addressing gaps in clinically useful evidence on drug-drug interactions" (R01LM011838)</p>
Clinical entity annotations for clinical cases in French: gold and silver standard annotations
<p>Clinical entity annotations (gold and silver annotation files) produced for the CAS/DEFT corpus of clinical cases in French used in the 2020 DEFT challenge. These annotations are released with the paper "Privacy-preserving mimic models for clinical named entity recognition in French" and are available in the BRAT Rapid Annotation Tool (BRAT) standoff format. </p>
Thyroid cancer harboring PTEN and TP53 mutations: A peculiar molecular and clinical case report
<p>To date, the molecular mechanisms that underline aggressiveness and resistance to tyrosine kinase inhibitors in some thyroid carcinomas (TCs) are not known yet. We report the case of a young patient with a metastatic poorly differentiated (PDTC) and follicular thyroid carcinoma (FTC) refractory to conventional therapies and to Sorafenib. The patient, despite an initial partial response, died of progressive disease 21 months after diagnosis. The genetic analysis performed on the primary tumor and on lymph nodes and distant metastases allowed to identify a frameshift mutation (p.P248Tfs*5) in the <em>PTEN</em> gene, never described in TC. This mutation was present in the primary tumor and, with a lower allelic frequency, in metastases diagnosed after treatment with Sorafenib. Mutations in <em>TP53</em> (p.C135Y and c.920-2A>G previously detected in anaplastic carcinomas and p.M133R never found in TC) were also detected in the primary tissue together with a mono-allelic expression of the p.C135Y mutant at RNA level. At metastatic sites level, we found only the <em>TP53</em> splicing mutation c.920-2A>G. The presence of defects in mismatch repair (MMR) proteins and genomic instability was also evaluated. The primary tumor showed a partial expression of MMR proteins together with a strong genomic instability. In conclusion, we demonstrated that the rare combination of somatic <em>PTEN</em> and <em>TP53</em> mutations in a patient with a metastatic FTC, together with the presence of tumor heterogeneity and genomic instability, might be associated with a high tumor aggressiveness and resistance to treatments.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.