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957 results for “conference”
Support data for conference paper "Service-Oriented Model for Handling mMTC Subscribers' Traffic in a 5G Cluster"
<p>Support data for conference paper<br>V. Kovtun, and O. Kovtun, “Service-Oriented Model for Handling mMTC Subscribers’ Traffic in a 5G Cluster.” In Proc. 5th 5th International Workshop on Intelligent Information Technologies & Systems of Information Security, CEUR-WS, vol. 3675, 2024; pp. 236-246.<br>This research is part of the project No. 2022/45/P/ST7/03450 co-funded by the National Science Centre and the European Union Framework Programme for Research and Innovation Horizon 2020 under the Marie Skłodowska-Curie grant agreement No. 945339.</p>
Support data for conference paper "The Concept of Efficient Utilization of the Uplink Frequency Resource of a Smart Factory 5G Cluster by IIoT Devices"
<p>upport data for conference paper<br>Kovtun, and O. Kovtun, “The Concept of Efficient Utilization of the Uplink Frequency Resource of a Smart Factory 5G Cluster by IIoT Devices.” In Proc. 8th International Conference on Computational Linguistics and Intelligent Systems. Volume I: Machine Learning Workshop, CEUR-WS, vol. 3664, 2024; pp. 273-283.<br>This research is part of the project No. 2022/45/P/ST7/03450 co-funded by the National Science Centre and the European Union Framework Programme for Research and Innovation Horizon 2020 under the Marie Skłodowska-Curie grant agreement No. 945339.</p>
Support data for conference paper "Assessment of Communication Resource Allocation by the Transmission Control Protocol for the Target Virtual Connection under Competitive Conditions"
<p>Support data for article</p> <p>V. Kovtun, O. Kovtun, K. Grochla, and K. Połys, “Assessment of Communication Resource Allocation by the Transmission Control Protocol for the Target Virtual Connection under Competitive Conditions,” Electronics, vol. 13, no. 7. MDPI AG, p. 1180, Mar. 22, 2024. doi: 10.3390/electronics13071180.</p> <div> <p>This research is part of the project No. 2022/45/P/ST7/03450 co-funded by the National Science Centre and the European Union Framework Programme for Research and Innovation Horizon 2020 under the Marie Skłodowska-Curie grant agreement No. 945339.</p> </div>
Dataset about conference paper "Toward the Sea or the Land Cultural Identity and the Choice of Direction of Movement on the Water"
<p>Dataset about conference paper "Toward the Sea or the Land Cultural Identity and the Choice of Direction of Movement on the Water". Including heritage sites, DEM, wind environment, least-cost corridor, and least-cost path.</p>
Wind Value: Second Conference 2024 End of Life Choices for Wind Farms, Video
<p>Video of Slides written by Dorcas Mikindani presented by Peter Deeney. The topic is the use of real options in wind farm valuation as a guide for decisions at end of life.</p>
Survey of Current Reproducibility Practices at IEEE Workshops and Conferences and in Journals
<p>The goal of the IEEE Reproducibility Practices Survey was to assess the reproducibility practices of IEEE journals, magazines, and conferences. IEEE Strategic Research (with Josephine Russo as the primary point of contact) executed the survey. As part of the survey, 422 IEEE conference organizers, magazine editor-in-chiefs, and journal editors-in-chiefs were surveyed using a self-administered, online questionnaire, yielding 132 responses for a response rate of 31%. A detailed report associated with this survey can be found at https://www.computer.org/volunteering/boards-and-committees/Open-Science-Reproducibility.</p>
An aphid symbiont confers protection against a specialized RNA virus, another increases vulnerability to the same pathogen
<p>Insects often harbor heritable symbionts that provide defense against specialized natural enemies, yet little is known about symbiont protection when hosts face simultaneous threats. In pea aphids (Acyrthosiphon pisum), the facultative endosymbiont Hamiltonella defensa confers protection against the parasitoid, Aphidius ervi, and Regiella insecticola protects against aphid-specific fungal pathogens, including Pandora neoaphidis. Here we investigated whether these two common aphid symbionts protect against a specialized virus A. pisum virus (APV), and whether their anti-fungal and anti-parasitoid services are impacted by APV infection. We found that APV imposed large fitness costs on symbiont-free aphids and these costs were elevated in aphids also housing H. defensa. In contrast, APV titers were significantly reduced and costs to APV infection were largely eliminated in aphids with R. insecticola. To our knowledge, R. insecticola is the first aphid symbiont shown to protect against a viral pathogen, and only the second arthropod symbiont reported to do so. In contrast, APV infection did not impact the protective services of either R. insecticola or H. defensa. To better understand APV biology, we produced five genomes and examined transmission routes. We found that moderate rates of vertical transmission, combined with horizontal transfer through food plants, were the major route of APV spread, although lateral transfer by parasitoids also occurred. Transmission was unaffected by facultative symbionts. In summary, the presence and species identity of facultative symbionts resulted in highly divergent outcomes for aphids infected with APV, while not impacting defensive services that target other enemies. These findings add to the diverse phenotypes conferred by aphid symbionts, and to the growing body of work highlighting extensive variation in symbiont-mediated interactions.</p>
Data from: Glutaredoxin regulation of primary root growth confers early drought stress tolerance in pearl millet
<p><span>Seedling root traits impact plant establishment under challenging environments. Pearl millet is one of the most heat- and drought-tolerant cereal crops that provides a vital food source across the sub-Saharan Sahel region. Pearl millet's early root system features a single fast-growing primary root which we hypothesize is an adaptation to the Sahelian climate. Using crop modelling, we demonstrate that early drought stress is an important constraint in agrosystems in the Sahel where pearl millet was domesticated. Furthermore, we show that increased pearl millet primary root growth is correlated with increased early water stress tolerance in field conditions. Genetics including GWAS and QTL approaches identify genomic regions controlling this key root trait. Combining gene expression data, re-sequencing and re-annotation of one of these genomic regions identified a glutaredoxin-encoding gene <em>PgGRXC9</em> as the candidate stress resilience root growth regulator. Functional characterization of its closest <em>Arabidopsis</em> homolog <em>AtROXY19</em> revealed a novel role for this glutaredoxin (GRX) gene clade in regulating cell elongation. In summary, our study suggests a conserved function for GRX genes in conferring root cell elongation and enhancing resilience of pearl millet to its Sahelian environment. </span></p>
Dataset for CFD4NRS-9 conference paper "Simulation of noble metal particle growth and removal in the molten salt fast reactor"
<p>Dataset used for the results presented in the CFD4NRS-9 conference paper "Simulation of noble metal particle growth and removal in the molten salt fast reactor". Also the code used to generate results is included (it is also publicly available at https://github.com/edofrederix/flotationFoam), and contains a README with instructions. The plots can be generated with their respective Python files.</p>
COMSOL simulation & example datasets for: Nonuniform structural properties of wings confer sensing advantages
<p>Sensory feedback is essential to both animals and robotic systems for achieving coordinated, precise movements. Mechanosensory feedback, which provides information about body deformation, depends not only on the properties of sensors but also on the structure in which they are embedded. In insects, wing structure plays a particularly important role in flapping flight: in addition to generating aerodynamic forces, wings provide mechanosensory feedback necessary for guiding flight while undergoing dramatic deformations during each wingbeat. However, the role that wing structure plays in determining mechanosensory information is relatively unexplored. Insect wings exhibit characteristic stiffness gradients and are subject to both aerodynamic and structural damping. Here we examine how both of these properties impact sensory performance, using finite element analysis combined with sensor placement optimization approaches. We show that wings with nonuniform stiffness exhibit several advantages over uniform stiffness wings, resulting in higher accuracy of rotation detection and lower sensitivity to the placement of sensors on the wing. Moreover, we show that higher damping generally improves the accuracy with which body rotations can be detected. These results contribute to our understanding of the evolution of the nonuniform stiffness patterns in insect wings, as well as suggest design principles for robotic systems.</p>
Does competitive asymmetry confer polyploid advantage under changing environments?
<p>Competitive interactions drive critical ecological processes in plant communities. Yet how competitive interactions are influenced by polyploidy which has a widespread incidence in plants remains largely unknown.</p> <p>To evaluate the hypothesis of competitive asymmetry between polyploids and diploids, we set up competing tetraploid and diploid plants of perennial herbaceous <em>Chrysanthemum indicum</em> L. (Asteraceae) at different relative frequencies under contrasting soil water contents. We quantified the interaction intensity between competing plants of the same (intraploidy) and different (interploidy) ploidy levels, and measured functional traits related to gas exchange and plant water use to understand the underlying mechanisms.</p> <p>The stronger competitive effect of tetraploids on diploids than that of diploids on tetraploids provided evidence for the competitive asymmetry. As a stronger competitor, tetraploids were limited more by individuals of their own than by diploids. Such competitive asymmetry was not only maintained under reduced soil water content, but also translated into higher aboveground biomass of tetraploids. Tetraploids showed more resource-acquisitive traits than diploids under high soil water content and more resource-conservative traits under reduced soil water content. As such, the higher trait plasticity in tetraploids than diploids likely explained the competitive asymmetry.</p> <p><em>Synthesis</em>. These results elucidate the nature and magnitude of species interactions between polyploid and diploid plants under changing environments and the underlying mechanisms, and provide important insights into the prevalence and persistence of polyploid plants under a changing climate.</p>
Biocuration 2023 Conference Booklet
A description of organizers, sponsors, speakers, and the schedule of the Biocuration 2023 Conference
Defensive symbiosis in the wild: seasonal dynamics of parasitism risk and symbiont-conferred resistance
<p class="MsoNormal"><span>Parasite-mediated selection can rapidly drive up resistance levels in host populations, but fixation of resistance traits may be prevented by costs of resistance. Black bean aphids (<em>Aphis fabae</em>) benefit from increased resistance to parasitoids when carrying the defensive bacterial endosymbiont <em>Hamiltonella defensa</em>. However, due to fitness costs that come with symbiont infection, symbiont-conferred resistance may result in either a net benefit or a net cost to the aphid host, depending on parasitoid presence as well as on the general ecological context. Balancing selection may therefore explain why in natural aphid populations, <em>H. defensa</em> is often found at intermediate frequencies.<strong> </strong>Here we present a two-year field study where we set out to look for signatures of balancing selection in natural aphid populations. We collected temporally well-resolved data on the prevalence of <em>H. defensa</em> in <em>A.f. fabae</em> and estimated the risk imposed by parasitoids using sentinel hosts.<strong> </strong>Despite a marked and consistent early-summer peak in parasitism risk and significant changes in symbiont prevalence over time, we found just a weak correlation between parasitism risk and <em>H. defensa </em>frequency dynamics. <em>H. defensa </em>prevalence in the populations under study was, in fact, better explained by the number of heat days that previous aphid generations were exposed to.<strong> </strong>Our study grants an unprecedentedly well-resolved insight into the dynamics of endosymbiont and parasitoid communities of <em>A.f. fabae </em>populations, and it adds to a growing body of empirical evidence suggesting that not only parasitism risk but rather multifarious selection is shaping <em>H. defensa</em> prevalence in the wild.</span></p>
Docking of chloroquine and piperaquine to PfCRT_Dd2 and to the PfCRT_Dd2 mutations conferring piperaquine resistance
<p>PDB files of the docking of chloroquine and piperaquine to the PfCRT_Dd2 variant and to the Dd2 mutants investigated</p> <p>reported in the manuscript</p> <p>"PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport"</p> <p>by Guillermo Martin Gomez; Giulia D'Arrigo; Fiona Berger; Cecilia P. Sanchez; Rebecca C. Wade and Michael Lanzer</p> <p>submitted to PLOS Pathogens</p> <p> </p> <p>1. <strong>Dockings.zip </strong>contains <strong>a)</strong> the individual pdb files of the PfCRT_Dd2 variants models prior to preparation with maestro and <strong>b)</strong> sub-folders with the docking results for each PfCRT_Dd2 variant and for PfCRT_7G8</p> <p>2. <strong>Simulations.zip </strong>contains the input file for the simulated systems. Each sub-folder contains:</p> <ul> <li>assembly.pdb - structure of the complex in PDB format</li> <li>assembly.prmtop - topology file in AMBER</li> <li>assembly.inpcrd - coordinates file in AMBER</li> <li>final.pdb - structure after NPT production</li> </ul>
56th CIRP Conference on Manufacturing Systems, CIRP CMS '23, South Africa - Enhancing SLM Stainless Steel: Model-Based Parameter Optimization
<p> SLM (selective laser melting) has faced challenges in ensuring consistent mechanical properties for various geometries in the past. However, the authors have developed a system that solves this issue by calculating the optimal process parameters for each scan vector on each layer. This approach ensures consistent melt pool geometry, derived from the most robust in conduction welding mode. The results from the single melt-line experiments and the presented thermal conduction solver demonstrate the effectiveness of this approach in achieving a stable melt pool geometry in stainless steel (1.4404 or 316L). Furthermore, a rigorous testing regimen has been implemented to evaluate the system under different changing boundary conditions, to further demonstrate its usefulness. By utilizing this system, manufacturers will achieve consistent and high-quality mechanical properties for small lot sizes, including spare and obsolescent parts.</p>
PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport
<p>These data were generated to investigate the effect of point mutations in PfCRT on the kinetics of chloroquine and piperaquine binding and transport. The protein confers resistance to a range of quinoline and quinoline-like antimalarials after the acquisition of certain amino acid substitutions, which occurs as a result of improper antimalarial use. The change in prescription from chloroquine (CQ) to piperaquine (PPQ) in Southeast Asian countries led to the emergence of a ninth mutation over the PfCRT Dd2 isoform, which renders the parasites resistant to piperaquine but re-sensitizes them to chloroquine. Despite structural information, how these individual mutations influence such opposing changes in the parasite's susceptibility to the aforementioned drugs remains unknown. Here, we show by biochemical studies that any of the piperaquine resistance-conferring mutations H97Y, F145I, M343L or G353V, either reduce the affinity of PfCRT Dd2 for CQ (Km) or reduce the efficiency of the transport cycle (Vmax). In parallel, they increase the Vmax, reduce the Km, or do both, in the case of PPQ transport. We also probed the binding cavity of PfCRT Dd2 and that of PfCRT Dd2_F145I, and found that it can readily bind both CQ and PPQ simultaneously, in a partial noncompetitive mechanism. We confirmed the latter finding through molecular docking and molecular dynamics simulations, describing for the first time the binding sites for both drugs in the cavity of PfCRT Dd2. With this, we found that the pocket where CQ binds seems to require an aromatic side chain, which is normally provided by F145, or by Y97 in the PPQ resistance-conferring H97Y mutant. Lastly, we generated an unnatural double mutant carrying both the H97Y and the F145I mutations. The engineered transporter displayed non-Michaelis-Menten kinetics both for CQ and PPQ transport and instead revealed sigmoidal kinetics, typical of proteins that bind substrate cooperatively. We thus provide new insights into the organization of the substrate-binding cavity of PfCRT and into the evolution of PfCRT.</p>
International E- Conference on "Recent Trends in Chemical Science, Physical Science, Life Science and Computer Technology (ICRTCPLCT–2022)
<p><strong>International E- Conference</strong> on “Recent Trends in Chemical Science, Physical Science, Life Science and Computer Technology (ICRTCPLCT–2022)” By Anjuman Islam Janjira Degree College of Science, Murud on <strong>29<sup>th</sup> March 2022.</strong></p>
International E-Conference On Post Covid-19 Situation
<p><strong>International E-Conference </strong>On <strong>Post Covid-19 Situation </strong>organized by<strong><em> Anjuman</em></strong> Islam Janjira Degree College of Science, Murud on <strong>30<sup>th</sup> March 2021 </strong></p>
Data for: Genome editing of an African elite rice variety confers resistance against endemic and emerging Xanthomonas oryzae pv. oryzae strains
<p class="MsoNormal"><span>Bacterial leaf blight (BB) of rice, caused by <em>Xanthomonas oryzae </em>pv<em>. oryzae</em> (<em>Xoo</em>), threatens global food security and the livelihood of small-scale rice producers.<em> </em>Analyses of <em>Xoo</em> collections from Asia, Africa and the Americas demonstrated complete continental segregation, despite robust global rice trade. Here, we report unprecedented BB outbreaks in Tanzania. The causative strains, unlike endemic African <em>Xoo</em>, carry Asian-type TAL effectors targeting the sucrose transporter <em>SWEET11a</em> and iTALes suppressing <em>Xa1</em>. Phylogenomics clustered these strains with <em>Xoo</em> from Southern-China. African rice varieties do not carry effective resistance. To protect African rice production against this emerging threat, we developed a hybrid CRISPR-Cas9/Cpf1 system to edit all known TALe-binding elements in three <em>SWEET</em> promoters of the East African elite variety Komboka. The edited lines show broad-spectrum resistance against Asian and African strains of <em>Xoo</em>, including strains recently discovered in Tanzania. The strategy could help to protect global rice crops from BB pandemics.</span></p>
Data for: Cooperative assembly confers regulatory specificity and long-term genetic circuit stability
<p>A ubiquitous feature of eukaryotic transcriptional regulation is cooperative self-assembly between transcription factors (TFs) and DNA cis-regulatory motifs. It is thought that this strategy enables specific regulatory connections to be formed in gene networks between otherwise weakly-interacting, low-specificity molecular components. Here, using synthetic gene circuits constructed in yeast, we find that high regulatory specificity can emerge from cooperative, multivalent interactions among artificial zinc finger-based TFs. We show that circuits 'wired' using the strategy of cooperative TF assembly are effectively insulated from aberrant misregulation of the host cell genome. As we demonstrate in experiments and mathematical models, this mechanism is sufficient to rescue circuit-driven fitness defects, resulting in genetic and functional stability of circuits in long-termcontinuous culture. Our naturally-inspired approach offers a simple, generalizable means for building high-fidelity, evolutionarily robust gene circuits that can be scaled to a wide range of host organisms and applications.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.