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136
datasets available to search
ShareScore release 0.9.0
Dataset results
136 results for “diet modelling”
Alteration of gene expression patterns in the liver and spleen following exposure to nucleoprotein diet in the mouse LPS injection model
GEO Series GSE28176. Mus musculus. 4 samples. Type: Expression profiling by array.
DNA methylation in mouse cancer model with ketogenic diet and mifepristone treatment
GEO Series GSE236260. Mus musculus. 442 samples. Type: Methylation profiling by genome tiling array.
Various forms of calorie restriction, but not a nonrestricted low-fat diet, reverse obesity-associated tumor growth and lung metastasis in a mouse model of triple-negative breast cancer-RRBS
GEO Series GSE202331. Mus musculus. 25 samples. Type: Methylation profiling by high throughput sequencing.
Genotype-by-diet interactions determine susceptibility and resistance in T2D mouse models [adipose]
GEO Series GSE234947. Mus musculus. 47 samples. Type: Expression profiling by high throughput sequencing.
Various forms of calorie restriction, but not a nonrestricted low-fat diet, reverse obesity-associated tumor growth and lung metastasis in a mouse model of triple-negative breast cancer-RNAseq
GEO Series GSE202330. Mus musculus. 29 samples. Type: Expression profiling by high throughput sequencing.
Genotype-by-diet interactions determine susceptibility and resistance in T2D mouse models [Dorsal Vagal Complex]
GEO Series GSE234951. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Genotype-by-diet interactions determine susceptibility and resistance in T2D mouse models [Hypothalamus]
GEO Series GSE235479. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Genotype-by-diet interactions determine susceptibility and resistance in T2D mouse models
GEO Series GSE235498. Mus musculus. 420 samples. Type: Expression profiling by high throughput sequencing.
Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes
GEO Series GSE230469. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Role of liquid sugar in regulating the hepatic transcriptome in a high fat Western diet model of NAFLD
GEO Series GSE89296. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer’s disease.
GEO Series GSE301153. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
A low protein diet drives short and long-term improvements in metabolic health in a mouse model of sleeve gastrectomy
GEO Series GSE307617. Mus musculus. 62 samples. Type: Expression profiling by high throughput sequencing.
Expression data from prostate tissues from mouse models of prostate cancer fed a high-fat diet or a control diet.
GEO Series GSE184381. Mus musculus. 10 samples. Type: Expression profiling by array.
The effect of lovastatin and fenofibrate in a short term diet-induced hyperlipidemia model in mice
GEO Series GSE6652. Mus musculus. 6 samples. Type: Expression profiling by array.
Various forms of calorie restriction, but not a nonrestricted low-fat diet, reverse obesity-associated tumor growth and lung metastasis in a mouse model of triple-negative breast cancer
GEO Series GSE202332. Mus musculus. 54 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
data set from Mollica G, Senesi P, Codella R, Vacante F, Montesano A, Luzi L, Terruzzi I. L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. Dig Liver Dis. 2020 Mar;52(3):314-323. doi: 10.1016/j.dld.2019.09.002. Epub 2019 Oct 10. PMID: 31607566.
<p>data set from Mollica G, Senesi P, Codella R, Vacante F, Montesano A, Luzi L, Terruzzi I. L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. Dig Liver Dis. 2020 Mar;52(3):314-323. doi: 10.1016/j.dld.2019.09.002. Epub 2019 Oct 10. PMID: 31607566.</p> <p> </p> <p>This is the abstract:</p> <p>Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disorder. NAFLD, associated lipotoxicity, fibrosis, oxidative stress, and altered mitochondrial metabolism, is responsible for systemic inflammation, which contributes to organ dysfunction in extrahepatic tissues, including the heart. We investigated the ability of L-carnitine (LC) to oppose the pathogenic mechanisms underlying NAFLD progression and associated heart dysfunction, in a mouse model of methionine-choline-deficient diet (MCDD). Mice were divided into three groups: namely, the control group (CONTR) fed with a regular diet and two groups fed with MCDD for 6 weeks. In the last 3 weeks, one of the MCDD groups received LC (200 mg/kg each day) through drinking water (MCDD + LC). The hepatic lipid accumulation and oxidative stress decreased after LC supplementation, which also reduced hepatic fibrosis via modulation of α-smooth muscle actin (αSMA), peroxisome-activated receptor gamma (PPARγ), and nuclear factor kappa B (NfƙB) expression. LC ameliorated systemic inflammation, mitigated cardiac reactive oxygen species (ROS) production, and prevented fibrosis progression by acting on signal transducer and activator of transcription 3 (STAT3), extracellular signal-regulated kinase 1-2 (ERK1-2), and αSMA. This study confirms the existence of a relationship between fatty liver disease and cardiac abnormalities and highlights the role of LC in controlling liver oxidative stress, steatosis, fibrosis, and NAFLD-associated cardiac dysfunction.</p> <p> </p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.