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329 results for “histopathology”
Figure 10 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 10. Transmission electron micrographs comparing energy and waste reserves in nonparasitized and Thripinema fuscum-parasitized Frankliniella fusca females including electrondense vesicles within the (A) fat body underlying the host cuticle and (B) midgut cells of a parasitized F. fusca; (C) an obvious depletion of glycogen (arrow) in the fat body and (D) a juvenile nematode with an accumulation of glycogen and lipid deposits probably sequestered from the host; (E) cross-section of healthy F. fusca muscle tissue and (F) of muscle tissue from a female parasitized by T. fuscum with the presence of numerous glycogen granules (arrowheads); (G) glycogen granules embedded between the muscle fibres and mitochondria in a parasitized female; (H) uric acid crystals formed from nitrogenous waste within the cytoplasm of a Malpighian tubule of a healthy female; (I) the accumulation of secretory vesicles and uric acid crystals in the cytoplasm of the Malpighian tubule of a parasitized host. Abbreviations: gly, glycogen; lp, lipid; mf, muscle fibres; mt, mitochondria; sv, secretory vesicle; tr, trachea; ua, uric acid crystals; ves, electron-dense vesicles. Scale bars: A, B, E, F, 2 µm; D, G, H 1 µm; C, I, 5 µm.
Figure 9. A in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 9. A healthy Frankliniella fusca female with (A) a robust reproductive system with developing eggs in the ovary; transmission electron micrographs showing (B) an ovariole in a healthy female with distinct follicle cells surrounding the developing oocyte and (C) the tight ladderlike extensions between the oocyte and follicle cell, the abundance of organelles in the oocyte, and the well-defined nucleus in the follicle cell; (D) a F. fusca female parasitized by Thripinema fuscum with a reduced reproductive system with atrophied ovary; transmission electron micrographs showing (E) the displacement of host ovarioles as a result of the numerous juvenile nematodes in abdominal haemocoele and (F) the tears in the ladder-like connections between the oocyte and follicle cell, the depletion of organelles in the oocyte, and the poorly defined nucleus. Abbreviations: n, nucleus; nem, nematode; org, organelles, ov, ovariole. Scale bars: A, D, 0.5 mm; B, E, 10 µm; C, F, 2 µm.
Figure 8 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 8. Scanning electron micrographs that show (A) numerous juvenile Thripinema fuscum juveniles aggregated longitudinally in the female Frankliniella fusca haemocoele and (B) the resulting compressed host midgut (arrow) with depressions. Scale bars: A, 75 µm; B, 30 µm.
Figure 7 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 7. Scanning electron micrographs of the free-living Thripinema fuscum female with (A) annulated cuticle with transverse striations and fully-developed mouth, (B) excretory pore on the anterior ventral surface, and (C) two lateral lines extending the length of the body. Scanning electron micrographs showing (D) the T. fuscum male with (E) copulatory structures including caudal alae, paired spicules and a gubernaculum. Abbreviations: ep, excretory pore; ll, lateral lines. Scale bars: A, 2.73 µm; B, 5 µm; C, 8.57 µm; D, 60 µm; E, 6 µm.
Figure 6 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 6. (A) Thick section of a Frankliniella fusca female 9 days after parasitization with an aggregation of late-staged Thripinema fuscum juveniles in the hindgut; scanning electron micrographs of a fractured F. fusca revealing (B, C) T. fuscum aggregation in hindgut with (D) a male (arrow) coiled around the females; (E) gross dissection of the F. fusca female host showing a nematode mass in the hindgut. Abbreviations: mt, Malpighian tubules; nem, nematodes. Scale bars: A, 100 µm; B, 231 µm; C, 50 µm; D, 30 µm; E, 250 µm.
Figure 2 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 2. The life cycle of Thripinema fuscum in (A) an adult female Frankliniella fusca host: (B) the progressive enlargement of the parasitic female (right to left); (C) eggs (=J1) produced by the parasitic female; (D–F) J2-stage through J3-stage juveniles; (G) infectious free-living females; (H) free-living male; (G) ingress of a free-living female regenerates the cycle. Scale bar: 200 µm.
Figure 4 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 4. Thripinema fuscum eggs: (A) thick section of a host Frankliniella fusca female 6 days after parasitization with abdominal cavity full of nematode eggs; (B) scanning electron micrographs of T. fuscum eggs including J1 embryos visible through egg chorion; (C) transmission electron micrograph of a T. fuscum embryo curled inside chorion in the host abdomen; scanning electron micrographs of (D) protuberances on the egg's surface and (E) aeropylar process on egg (arrow), (F) eggs cushioned within host fat body, and (G) host immune factors on the egg surface. Abbreviations: nem eggs, nematode eggs. Scale bars: A, 100 µm; B, 10 µm; C, 30 µm; D, G, 2 µm; E, 1.2 µm; F, 30 µm.
Figure 5 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 5. Thripinema fuscum juveniles: (A) transmission electron micrograph documenting various cuticular structures; (B) scanning electron micrographs showing the host factors adhered to the cuticle surface, (C) shedding of the cuticle, (D) transmission electron micrograph of a juvenile completing ecdysis as evidenced by the shed outer cuticle (arrow) and the assembly of a new cuticle peripheral to the hypodermis, and (E) scanning electron micrograph of the developing mouthparts with visible stylet. Scale bars: A, 0.5 µm; B, E, 2 µm; C, 4.3 µm; D, 3.75 µm.
Figure 1 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 1. (A) Dorsal view of a non-parasitized (right) and parasitized (left) Frankliniella fusca female; (B) a non-parasitized female with eggs and (C) a parasitized female with three parasitic Thripinema fuscum females and progeny; thick sections of (D) a non-parasitized F. fusca female and (E) a parasitized F. fusca female. Abbreviations: mg, midgut; fb, fat body; nem, nematode; ov, ovary; ves, electron-dense vesicle. Scale bars: A–C, 0.5 mm; D, E, 100 µm.
Figure 3 in The morphology and biology of the entomophilic Thripinema fuscum (Tylenchida: Allantonematidae), and the histopathological effects of parasitism on the host Frankliniella fusca (Thysanoptera: Thripidae)
Figure 3. Thripinema fuscum parasitic female: (A) differential interference contrast microscope image of the dorsal view of a fecund female; scanning electron micrographs of the external surface with (B) pit-like structures and (C) knob-like projections; transmission electron micrographs of the external cuticle with (D) microvilli and (E) knob-like projection; transmission electron micrographs of (F) the parasitic female in direct apposition to host midgut with (G) microvilliated cuticular surface of the parasitic female touching the basement membrane of the host midgut; (H) thick section of a Frankliniella fusca female 3 days after parasitization with a parasitic T. fuscum female with eggs (arrowheads) constricting the host midgut lumen. Abbreviations: mg, midgut; pf, parasitic female. Scale bars: A, 50 µm; B, 667 nm; C, 300 nm; D, E, G, 1 µm; F, 10 µm; H, 100 µm.
Histopathology images for end-to-end AI, based on TCGA-BRCA
<p>These are histopathological images which are derived from the TCGA-BRCA breast cancer histology dataset at https://portal.gdc.cancer.gov/ (please check this website for the original data license). They can be used for end-to-end artificial intelligence (AI) workflows such as DeepMed (https://github.com/KatherLab/deepmed) which aim to predict high-level features directly from digital images with weakly supervised transfer learning. Here, we use two subsets of these digitized images:</p> <p>1) TCGA-BRCA-A2, these are all images from Walter Reed National Military Medical Center (tissue source site code A2, N=100 images) in the TCGA-BRCA database (tcga-brca-a2-deepmed-tiles.zip)</p> <p>2) TCGA-BRCA-E2, these are all images from Roswell Park Comprehensive Cancer Center (tissue source site code E2, N=90 images) in the TCGA-BRCA database (tcga-brca-e2-deepmed-tiles.zip)</p> <p>see also https://gdc.cancer.gov/resources-tcga-users/tcga-code-tables/tissue-source-site-codes </p> <p>The images were preprocessed according to the Aachen Protocol for Deep Learning Histopathology which is available at https://zenodo.org/record/3694994. Specifically, digital whole slide images (SVS format) of hematoxylin & eosin (H&E) stained slides were tessellated (without manual annotations) into tiles of 256x256 px edge length at 1 µm/px. Then, images were color-normalized using the Macenko method as described before (https://www.nature.com/articles/s43018-020-0087-6) and saved as JPEG files. For the A2 cohort, an additional ZIP archive is provided in which only 100 random image tiles are saved for each patient (tcga-brca-a2-deepmed-tiles_100.zip). In addition, we provide a CLINI and a SLIDE table as defined in the "Aachen Protocol". The CLINI table contains clinico-pathological data for all included patients and it is derived from clinical information on www.cbioportal.org as well as from Thorsson et al. (https://pubmed.ncbi.nlm.nih.gov/29628290/). We recommend to use the A2 dataset for training and the E2 dataset for testing. Please cite the relevant papers if you re-use this dataset, more information is available on www.kather.ai</p>
Multi-channel auto-encoders for learning domain invariant representations enabling superior classification of histopathology images
<p>A partially synthetic histopathology dataset containing image patches of colon tissue from 3 staining and scanning conditions.</p> <p>This dataset can be used to develop novel histopathology image analysis algorithms that are better able to generalise to novel data domains.</p> <p>See repo for more information.</p>
Canine mammary tumors histopathological image classification by computer-aided pathology_ supplementary files
<p>Supplementary files</p>
Master Data for Histopathology
<p>Master data for the article of Comparison between premortem histopathology findings in rats with and without traumatic brain injury: Prospective application in forensic medicine.</p>
Study of Nasal Mucosa Histopathological Changes in Chronic Hypersensitivity Pneumonitis
ClinicalTrials.gov study NCT05723796. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases
ClinicalTrials.gov study NCT06208397. IPD Sharing: NO. Countries: 1. Publications: 4.
Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Inju
ClinicalTrials.gov study NCT05728216. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Endoscopic I-scan Versus Histopathological Evaluation Of Esophageal Lesions
ClinicalTrials.gov study NCT05876702. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Histopathological Comparison Between Superficial Pressure Ulcers and Incontinence-associated Dermatitis
ClinicalTrials.gov study NCT03685929. IPD Sharing: NO. Countries: 1. Publications: 1.
Is Routine Use of Histopathological Examination Necessary After Cholecystectomy ?
ClinicalTrials.gov study NCT02654873. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.