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322
datasets available to search
ShareScore release 0.9.0
Dataset results
322 results for “hypoglycemia”
Study of Insulin Pump in Prevention of Low Glucose Events in Adults With Type 1 Diabetes at Risk of Severe Hypoglycemia
ClinicalTrials.gov study NCT02657213. IPD Sharing: NO. Countries: 1. Publications: 1.
Effect of Antenatal Corticosteroids on Neonatal Hypoglycemia
ClinicalTrials.gov study NCT06716918. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Reducing Hypoglycemia Fear in Parents of Young Children With Type 1 Diabetes
ClinicalTrials.gov study NCT03879642. IPD Sharing: NO. Countries: 0. Publications: 3.
Cerebral Responses to Insulin Induced Hypoglycemia
ClinicalTrials.gov study NCT02747680. IPD Sharing: NO. Countries: 1. Publications: 0.
The Role of 1.5-anhydro-D-glucitol as Clinical Biomarkers of Hypoglycemia in Patients With Diabetes
ClinicalTrials.gov study NCT02068300. IPD Sharing: NO. Countries: 1. Publications: 1.
Evaluation of the Effect of Hypoglycemia With PET and a Norepinephrine Transporter Ligand
ClinicalTrials.gov study NCT02056249. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Paternal Touch on Sucking Performance, Comfort, and Glucose Levels in Newborns at Risk for Hypoglycemia
ClinicalTrials.gov study NCT07302412. IPD Sharing: NO. Countries: 0. Publications: 4.
Home Video-based Telemedicine to Reduce Hypoglycemia Fear in Parents of Young Children
ClinicalTrials.gov study NCT03914547. IPD Sharing: NO. Countries: 1. Publications: 1.
Revisiting peak serum cortisol response to insulin-induced hypoglycemia in children and adolescents
<p>Purpose: To evaluate factors that could potentially affect the hypothalamic-pituitary adrenal (HPA) axis response to insulin-induced hypoglycemia in children without history or symptoms of adrenal insufficiency and to propose a cut-off value to define a normal response in this population. Methods: Exploratory single-centre study involving 78 children that prospectively underwent insulin tolerance test (ITT) for suspected growth hormone (GH) deficiency. Methods: Glucose, cortisol, GH, adrenocorticotropic hormone (ACTH), epinephrine and norepinephrine levels were measured at baseline and after insulin-induced hypoglycemia. Serum cortisol was measured using Access automated immunoassay. Results: Mean (range) basal morning serum cortisol of 8 (2.2-19.5) µg/dL/ 222 (61-542) nmol/L increased after hypoglycemia to 20.5 (14.6-29.5) µg/dL / 570 nmol/L (405 -819) nmol/L. Peak serum cortisol levels of 14.6 µg/dL (405nmol/L) and 15.4 µg/dL (428 nmol/L) corresponded to the 2.5<sup>th</sup> and 5<sup>th</sup> percentiles, respectively. Peak serum cortisol correlated with peak plasma epinephrine (r = 0.367; <em>P</em> = 0.0014) but did not correlate with age, BMI-SD or peak serum GH. Children with intact and abnormal GH responses presented similar mean peak serum cortisol levels (20.0 vs. 20.6 µg/dL / 555 vs. 572 nmol/L; <em>P</em> = 0.21). Conclusion: Our data indicate that the current cut-off to define normal HPA axis response in children after insulin-induced hypoglycemia warrants reevaluation in order to avoid overdiagnosis of adrenal insufficiency. Our results suggest that peak serum cortisol levels ³ 15.4 µg/dL (428 nmol/L) in children undergoing ITT might represent a normal cortisol response to stress, regardless of age, BMI or GH secretory capacity.</p>
Data from: Hypoglycemia Following intravenous insulin plus glucose for hyperkalemia in patients with impaired renal function
Background: Hypoglycemia is a serious complication following the administration of insulin for hyperkalemia. We determined the incidence of hypoglycemia and severe hypoglycemia (blood glucose <70 or ≤40 mg/dl, respectively) in a cohort of AKI and non-dialysis dependent CKD patients who received an intravenous infusion of insulin plus glucose to treat hyperkalemia. Methods: We retrospectively reviewed charts of all AKI and non-dialysis dependent CKD patients who received 10 U of insulin plus 50 g glucose to treat hyperkalemia from December 1, 2013 to May 31, 2015 at our Department. Results: One hundred sixty four episodes of hyperkalemia were treated with insulin plus glucose and were eligible for analysis. Serum potassium levels dropped by 1.18 ± 1.01 mmol/l. Eleven treatments (6.1%) resulted in hypoglycemia and two (1.2%) in severe hypoglycemia. A lower pretreatment blood glucose tended to associate with a higher subsequent risk of hypoglycemia. Age, sex, renal function, an established diagnosis of diabetes or previous treatment were not associated with the development of this complication. We did not register any significant adverse events. Conclusion: Our intravenous regimen combining an infusion of insulin plus glucose effectively reduced serum potassium levels compared to previous studies and associated a low risk of symptomatic hypoglycemia and other complications.
Treatment of Hypoglycemia Following Gastric Bypass Surgery
ClinicalTrials.gov study NCT02527993. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Carvedilol in Treating Hypoglycemia Unawareness
ClinicalTrials.gov study NCT03538015. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Usability of Intranasal Glucagon in Treatment of Hypoglycemia
ClinicalTrials.gov study NCT02171130. IPD Sharing: YES. Countries: 2. Publications: 0.
Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia
ClinicalTrials.gov study NCT01972152. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Hypoglycemia and Autonomic Nervous System Function-B
ClinicalTrials.gov study NCT03429946. IPD Sharing: YES. Countries: 1. Publications: 0.
CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism
ClinicalTrials.gov study NCT02937558. IPD Sharing: NO. Countries: 1. Publications: 0.
Hypoglycemia Prediction Model
ClinicalTrials.gov study NCT03006510. IPD Sharing: Not stated. Countries: 0. Publications: 11.
Closed Loop and Education for Hypoglycemia Awareness Restoration
ClinicalTrials.gov study NCT06325202. IPD Sharing: YES. Countries: 3. Publications: 0.
IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase
ClinicalTrials.gov study NCT04028960. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Amitriptyline in Treating Hypoglycemia
ClinicalTrials.gov study NCT03591458. IPD Sharing: NO. Countries: 1. Publications: 0.
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International Brain Laboratory public data
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OpenNeuro
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