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1,048 results for “interpreting”
Tissue-aware interpretation of genetic variants advances the etiology of rare diseases
<p>Pathogenic variants underlying Mendelian diseases often disrupt the normal physiology of a<br>few tissues and organs. However, variant effect prediction tools that aim to identify<br>pathogenic variants are typically oblivious to tissue contexts. Here we report a machine-<br>learning framework, denoted ‘Tissue Risk Assessment of Causality by Expression for<br>variants’ (TRACEvar, https://netbio.bgu.ac.il/TRACEvar/), that offers two advancements.<br>First, TRACEvar predicts pathogenic variants that disrupt the normal physiology of specific<br>tissues. This was achieved by creating 14 tissue-specific models that were trained on over<br>14,000 variants and combined 84 attributes of genetic variants with 495 attributes derived<br>from tissue omics. TRACEvar outperformed 10 well-established and tissue-oblivious variant<br>effect prediction tools. Second, the resulting models are interpretable, thereby illuminating<br>variants' mode-of-action. Application of TRACEvar to variants of 52 rare-disease patients<br>highlighted pathogenicity mechanisms and relevant disease processes. Lastly, interpretation<br>of large-scale models revealed that top-ranking determinants of pathogenicity included<br>attributes of disease-affected tissues, particularly cellular process activities. Hence, tissue<br>contexts and interpretable machine-learning models can greatly enhance the etiology of rare<br>diseases.</p> <p>Article link: https://www.embopress.org/doi/full/10.1038/s44320-024-00061-6</p> <p> </p>
◂Fig. 6 Gynoecial development, fruit and seedling of C. crenata %yellow frames), C. cf. grandicalyx %blue frames) and C. sinensis %pink frames; A–F light microscopy, G–K stereo microscopy of endocarp, mesocarp removed; L–O field images; TS in horizontal orientation). A, B TS of anthetic flower %note two to three abortive ovules and strongly stained, peripheral tissue). C, D TS of anthetic flower %note two to three abortive ovules and lignifying portions of prospective mesocarp). E Young fruit %note developing endocarp and flashily pink portions of the mesocarp). F TS of postanthetic flower %note three abortive ovules and lignifying portions of prospective mesocarp). G TS of endocarp, with three developed embryos removed %note scanty endosperm). H Endocarp. J TS of endocarp. K Endocarp. L Immature fruits. M Mature fruits. N Seedlings %note short hypocotyl and long petioles of cotyledons). O Seedlings %note long hypocotyl and short petioles of cotyledons; image taken from cultivated plant, accession number 2012–0005, in the Botanical Garden Munich) %LS, longisection; TS, transverse section; ao, abortive ovule; cot, cotyledon; db, dorsal bundle; c, calyx; ec, endocarp; ens, endosperm; ex, exocarp; fr, fruit; h, hypocotyl; int, integument; lb, lateral bundle; mc, mesocarp; o, ovule; pet, petiolus; sty, style; ut, peripheral tissue; vs, ventral slit) in Observations on flower and fruit anatomy in dioecious species of Cordia (Cordiaceae, Boraginales) with evolutionary interpretations
◂Fig. 6 Gynoecial development, fruit and seedling of C. crenata %yellow frames), C. cf. grandicalyx %blue frames) and C. sinensis %pink frames; A–F light microscopy, G–K stereo microscopy of endocarp, mesocarp removed; L–O field images; TS in horizontal orientation). A, B TS of anthetic flower %note two to three abortive ovules and strongly stained, peripheral tissue). C, D TS of anthetic flower %note two to three abortive ovules and lignifying portions of prospective mesocarp). E Young fruit %note developing endocarp and flashily pink portions of the mesocarp). F TS of postanthetic flower %note three abortive ovules and lignifying portions of prospective mesocarp). G TS of endocarp, with three developed embryos removed %note scanty endosperm). H Endocarp. J TS of endocarp. K Endocarp. L Immature fruits. M Mature fruits. N Seedlings %note short hypocotyl and long petioles of cotyledons). O Seedlings %note long hypocotyl and short petioles of cotyledons; image taken from cultivated plant, accession number 2012–0005, in the Botanical Garden Munich) %LS, longisection; TS, transverse section; ao, abortive ovule; cot, cotyledon; db, dorsal bundle; c, calyx; ec, endocarp; ens, endosperm; ex, exocarp; fr, fruit; h, hypocotyl; int, integument; lb, lateral bundle; mc, mesocarp; o, ovule; pet, petiolus; sty, style; ut, peripheral tissue; vs, ventral slit)
◂Fig. 4 Gynoecium of C. crenata %yellow frames), C. cf. grandicalyx %blue frames) and C. sinensis %pink frames; A–R light microscopy; TS in horizontal orientation). A Secantial section. B, C TS %note cellular organisation). D Secantial section. E, F TS %note cellular organisation). G Secantial section of young gynoecium showing cellular organisation. H–J TS %note lacking cellular organisation, localisation in K–M). K–M LS at different levels from outside to inside of the same specimen %note strongly stained peripheral tissue; asterisks indicate tissue illustrated in H–J). N TS %note dehiscence lines of the prospective endocarp). O, P TS showing transmission tissue and dorsal bundles at top of style. Q vascularisation at base of gynoecium %note strongly stained peripheral tissue). R Vascularisation at base of flower %LS, longisection; TS, transverse section; db, dorsal bundle; dl, dehiscent line; ep, epidermis; lb, lateral bundle; tt, transmission tissue; ut, peripheral tissue; vb, ventral bundle; vs, ventral slit) in Observations on flower and fruit anatomy in dioecious species of Cordia (Cordiaceae, Boraginales) with evolutionary interpretations
◂Fig. 4 Gynoecium of C. crenata %yellow frames), C. cf. grandicalyx %blue frames) and C. sinensis %pink frames; A–R light microscopy; TS in horizontal orientation). A Secantial section. B, C TS %note cellular organisation). D Secantial section. E, F TS %note cellular organisation). G Secantial section of young gynoecium showing cellular organisation. H–J TS %note lacking cellular organisation, localisation in K–M). K–M LS at different levels from outside to inside of the same specimen %note strongly stained peripheral tissue; asterisks indicate tissue illustrated in H–J). N TS %note dehiscence lines of the prospective endocarp). O, P TS showing transmission tissue and dorsal bundles at top of style. Q vascularisation at base of gynoecium %note strongly stained peripheral tissue). R Vascularisation at base of flower %LS, longisection; TS, transverse section; db, dorsal bundle; dl, dehiscent line; ep, epidermis; lb, lateral bundle; tt, transmission tissue; ut, peripheral tissue; vb, ventral bundle; vs, ventral slit)
◂Fig. 3 Gynoecium of C. crenata %yellow frames), C. cf. grandicalyx %blue frames) and C. sinensis %pink frames; A, B stack shot images; C–K light microscopy; G polarised light; TS in horizontal orientation). A, B Anthetic female flower, calyx and corolla partly removed. B LS of gynoecium. C LS of functionally female flower %note strongly stained peripheral tissue of corolla, anther and gynoecium). D LS of gynoecium. E, F TS of functionally female flower %note strongly stained, peripheral tissue). G TS of functionally female flower %note crystal deposition). H LS of ovule %note stalked embryo sac). J TS of functionally male flower with non-functional ovules. K LS of functionally male flower %style lacking, original position indicated by an asterisk) %LS, longisection; TS, transverse section; a,anther; bs, basal septum; c, calyx; car, carpel; co, corolla; db, dorsal bundles; es, embryo sac; fs, false septum; lb, lateral bundles; o, ovule; stg, stigma; sty, style; t, trichomes; tt, transmission tissue; ut, peripheral, strongly stained tissue; vb, ventral bundles; vs, ventral slit) in Observations on flower and fruit anatomy in dioecious species of Cordia (Cordiaceae, Boraginales) with evolutionary interpretations
◂Fig. 3 Gynoecium of C. crenata %yellow frames), C. cf. grandicalyx %blue frames) and C. sinensis %pink frames; A, B stack shot images; C–K light microscopy; G polarised light; TS in horizontal orientation). A, B Anthetic female flower, calyx and corolla partly removed. B LS of gynoecium. C LS of functionally female flower %note strongly stained peripheral tissue of corolla, anther and gynoecium). D LS of gynoecium. E, F TS of functionally female flower %note strongly stained, peripheral tissue). G TS of functionally female flower %note crystal deposition). H LS of ovule %note stalked embryo sac). J TS of functionally male flower with non-functional ovules. K LS of functionally male flower %style lacking, original position indicated by an asterisk) %LS, longisection; TS, transverse section; a,anther; bs, basal septum; c, calyx; car, carpel; co, corolla; db, dorsal bundles; es, embryo sac; fs, false septum; lb, lateral bundles; o, ovule; stg, stigma; sty, style; t, trichomes; tt, transmission tissue; ut, peripheral, strongly stained tissue; vb, ventral bundles; vs, ventral slit)
Datasets for explanation of physical interpretation for locational marginal prices
<p>Matlab/Octave functions that extract the following information</p> <p>Initial: </p> <p>[rus] Исходная схема IEEE-30 в формате MATPOWER [1]. По сравнению с case30 cкорректированы ограничения на переток мощности в линиях.</p> <p>[eng] Initial case IEEE-30 in MATPOWER format [1]. With comparison with case30 line rates were corrected</p> <p>Base:</p> <p>[rus] Результаты оптимизации в MATPOWER со следующими настройками:</p> <p>[eng] Optimization results in MATPOWER with following options:</p> <p>mpopt = mpoption('opf.ac.solver','MIPS','out.all', outall,...<br> 'opf.flow_lim','P');<br> <br> [mpc, exitflagac]=runopf(mpc,mpopt);</p> <p>coeffs:</p> <p>[rus] Коэффициенты режимной компоненты, компонент, обусловленных сетевыми ограничениями и ограничениями по напряжению. Отклики в задачах расчета установившегося режима и оптимизации установившегося режима.</p> <p>[eng] LMP weights of power flow, transmission constraints, and voltage constraints components. Derivatives in power flow and optimal power flow problems.</p> <p>Model_1204:</p> <p>[rus] Результаты оптимизации в MATPOWER с заменой заявки второго генератора на 1204</p> <p>[eng] Optimization results in MATPOWER with new offer price 1204 for second generator.</p> <p>Model_775:</p> <p>[rus] Результаты оптимизации в MATPOWER с заменой заявки генератора 27 на 775</p> <p>[eng] Optimization results in MATPOWER with new offer price 775 for generator 27.</p>
A Corpus-driven Study of Contrastive Markers in Cantonese‒English Political Interpreting-Figure 4. The frequency of different source segments of "but" in the Cantonese sub-corpus
<p>Likewise, Figure 4 lists all the Cantonese source segments of but and their frequency. The results show that most of the use of but was contributed by daan (hai) — its closest equivalence in Cantonese. However, there were 52 instances of the use of but which corresponded to no source segments at all in the Cantonese sub-corpus, indicating, again, the possibility of explicitation. The rest of the 16 instances of but were attributed by the use of the Cantonese markers ji (而 (frequency=8; close in meaning to however and but, indicating concession or contrast), followed by bat gwo (frequency=7) and koek (卻 (frequency=1; close in meaning to however and but, indicating concession or contrast).</p>
A Corpus-driven Study of Contrastive Markers in Cantonese‒English Political Interpreting-Figure 3. The frequency of different source segments of "however" in the Cantonese sub-corpus
<p>The use of however and but in the English sub-corpus was also investigated through looking into their source segments in the Cantonese sub-corpus. Figure 3 lists all the Cantonese source segments of however and their frequency. The figures show that the use of however mostly resulted from the employment of daan (hai) in the Cantonese source text (frequency=52). There were 24 instances of however which corresponded to no source segment at all, indicating a possible trend of explicitation — a feature of interpreted or translated language. Only 21 cases of however were caused by the use of bat gwo — its closest equivalence in Cantonese. The rest 4 cases resulted from the use of the Cantonese marker ho si (可是) (frequency=3; close in meaning to both however and but in English, indicating concession or contrast) and zeon gun (儘管 (frequency=1; close in meaning to although or in spite of in English, indicating concession or topic change).</p>
A Corpus-driven Study of Contrastive Markers in Cantonese‒English Political Interpreting-Figure 2. The frequency of different renditions of "daan (hai)" in the English sub-corpus
<p>The renditions of daan (hai) show a similar pattern (Figure 2). Among the 287 cases of daan (hai), the majority were interpreted into but (frequency=74) — its closest equivalence in English that signals denial and contrast. A total of 60 daan (hai) received no interpretation at all, which, again, indicates a possible mitigation strategy employed by the interpreter(s). Similar to the case of bat gwo, however — the other frequently used English marker apart from but — was the next most often employed rendition of daan (hai) in the English sub-corpus. In addition to but and however, daan (hai) was also rendered into the following English markers: although, despite, while, nevertheless, yet, having said that / that said, nonetheless, though, notwithstanding, on the other, regardless, even so, and after, most of which signal concession and topic change, with an even higher degree of subtlety as compared to however.</p>
A Corpus-driven Study of Contrastive Markers in Cantonese‒English Political Interpreting-Figure 1. The frequency of different renditions of "bat gwo" in the English sub-corpus
<p>The renditions of bat gwo and daan (hai) were closely examined by looking into how they were interpreted. Figure 1 lists all the renditions of bat gwo and their frequency. The figures show that bat gwo was most often interpreted into however (frequency=22) — its closest equivalence in English. There were, however, 7 cases that bat gwo was interpreted into but — its stronger and less subtle correspondence that indicates denial and contrast. Apart from rendering into these two most common English contrastive markers, there were also 5 cases that bat gwo was not interpreted at all, suggesting a possible mitigation strategy employed by the interpreter(s). Likewise, the rest of bat gwo were rendered into other markers including nevertheless, nonetheless, while, yet, having said that / that said, all of which indicate concession and topic change, yet with an even higher degree of subtlety as compared to however.</p>
netDx: Interpretable patient classification using integrated patient similarity networks
<p>Docker image containing installed netDx software in Ubuntu to reproduce examples from the published manuscript. The R implementation of netDx is hosted at: https://github.com/BaderLab/netDx</p> <p>---<br> Publication abstract: Patient classification has widespread biomedical and clinical applications, including diagnosis, prognosis and treatment response prediction. A clinically useful prediction algorithm should be accurate, generalizable, be able to integrate diverse data types, and handle sparse data. A clinical predictor based on genomic data needs to be easily interpretable to drive hypothesis-driven research into new treatments. We describe netDx, a novel supervised patient classification framework based on patient similarity networks. netDx meets the above criteria and particularly excels at data integration and model interpretability. We compared classification performance of this method against other machine-learning algorithms, using a cancer survival benchmark with four cancer types, each requiring integration of up to six genomic and clinical data types. In these tests, netDx has significantly higher average performance than most other machine-learning approaches across most cancer types. In comparison to traditional machine learning-based patient classifiers, netDx results are more interpretable, visualizing the decision boundary in the context of patient similarity space. When patient similarity is defined by pathway-level gene expression, netDx identifies biological pathways important for outcome prediction, as demonstrated in diverse data sets of breast cancer and asthma. Thus, netDx can serve both as a patient classifier and as a tool for discovery of biological features characteristic of disease. We provide a freely available software implementation of netDx along with sample files and automation workflows in R.</p>
Dataset: Modeling the Dielectric Properties of Minerals from Crystals to Bulk Powders for Improved Interpretation of Asteroid Radar Observations
<p>Data (measurements of scattering parameters of samples) presented in: Hickson ,D.C., Boivin, A.L., Tsai, C.A., Daly, M.G. and Ghent, R.R. (2020) Modeling the Dielectric Properties of Minerals from Crystals to Bulk Powders for Improved Interpretation of Asteroid Radar Observations. <em>Journal of Geophysical Research: Planets, 125, </em>e2019JE006141. https://doi.org/10.1029/2019JE006141</p>
Database of Irish language court interpreters 1754-1921
<p>This database formed the basis of a monograph <em>Irish Speakers, Interpreters and the Courts</em> published by Four Courts Press and the Irish Legal History Society in 2019.</p> <p>The file is divided into five sections:</p> <p>Section I consists of all records found for Grand Jury payments to Irish language court interpreters in each county from the earliest record in Donegal in 1754 to some very late records in Kerry in the 1940s. Tables are organised by year and by county and where available interpreters' names are included making it possible to establish the length of their careers. These records are supplemented by digitised newspaper records and almanacs.</p> <p>Section II is based on mentions of interpreters in correspondence with the Chief Secretary's Office at Dublin Castle, information extracted from the Registered Papers</p> <p>Section III links in with Section II and consists of mentions of interpreters in the form of copies of replies in the country letter books to letters received by the Chief Secretary's Office.</p> <p>Section IV focuses on National Archives of Ireland files on the Maamtrasna trials held in Dublin in 1882.</p> <p>Section V consists of transcripts of letters of application for the post of interpreter in Mayo in 1893.</p> <p> </p>
Newspaper references to Irish language Court Interpreters 1796-1922
<p>This file consists of a corpus made up of transcriptions of newspaper extracts that mention Irish language court interpreters. Much of the information was used in <em>Irish Speakers, Interpreter and the Courts</em> (2019) by Mary Phelan, published by Four Courts Press and the Irish Legal History Society.</p>
Link to Dataset related to article "Interpreting Non-coding Genetic Variation in Multiple Sclerosis Genome-Wide Associated Regions"
<p>Link to Dataset related to article "Interpreting Non-coding Genetic Variation in Multiple Sclerosis Genome-Wide Associated Regions"</p> <p>Multiple sclerosis (MS) is the most common neurological disorder in young adults. Despite extensive studies, only a fraction of MS heritability has been explained, with association studies focusing primarily on protein-coding genes, essentially for the difficulty of interpreting non-coding features. However, non-coding RNAs (ncRNAs) and functional elements, such as super-enhancers (SE), are crucial regulators of many pathways and cellular mechanisms, and they have been implicated in a growing number of diseases. In this work, we searched for possible enrichments in non-coding elements at MS genome-wide associated loci, with the aim to highlight their possible involvement in the susceptibility to the disease. We first reconstructed the linkage disequilibrium (LD) structure of the Italian population using data of 727,478 single-nucleotide polymorphisms (SNPs) from 1,668 healthy individuals. The genomic coordinates of the obtained LD blocks were intersected with those of the top hits identified in previously published MS genome-wide association studies (GWAS). By a bootstrapping approach, we hence demonstrated a striking enrichment of non-coding elements, especially of circular RNAs (circRNAs) mapping in the 73 LD blocks harboring MS-associated SNPs. In particular, we found a total of 482 circRNAs (annotated in publicly available databases) vs. a mean of 194 ± 65 in the random sets of LD blocks, using 1,000 iterations. As a proof of concept of a possible functional relevance of this observation, we experimentally verified that the expression levels of a circRNA derived from an MS-associated locus, i.e., hsa_circ_0043813 from the <em>STAT3</em> gene, can be modulated by the three genotypes at the disease-associated SNP. Finally, by evaluating RNA-seq data of two cell lines, SH-SY5Y and Jurkat cells, representing tissues relevant for MS, we identified 18 (two novel) circRNAs derived from MS-associated genes. In conclusion, this work showed for the first time that MS-GWAS top hits map in LD blocks enriched in circRNAs, suggesting circRNAs as possible novel contributors to the disease pathogenesis.</p> <p>GEO database</p> <p>URL: <a href="https://www.ncbi.nlm.nih.gov/geo/">https://www.ncbi.nlm.nih.gov/geo/</a></p> <p>Numero di accesso del dataset: GSE110525</p>
Text-fig. 2. A – Elasmobranchii gen. et spec. indet. specimen NM Pc 02876b; B – Scopeloides glarisianus dentary NM Pc 02888 (the white arrows mark the tips of the "fang-like" teeth); C – S. glarisianus disarticulated skeleton NM Pc 02887a; D – Sardinella sardinites scale NM Pc 02886; E – Clupeidae gen. et spec. indet. articulated skeleton without head NM Pc 02889; F – Anenchelum glarisianum body fragment NM Pc 02880a; G – Percoidei gen. et sp. indet. preoperculum (G-1) and its interpretation (G-2) NM Pc 02891. The arrow shows the enlarged spine in the angle between rami verticalis and horizontalis. Abbreviations: cl – cleithrum; op – operculum; pcl – postcleithrum. in An Annotated List Of The Oligocene Fish Fauna From The Osíčko Locality (Menilitic Fm.; Moravia, The Czech Republic)
Text-fig. 2. A – Elasmobranchii gen. et spec. indet. specimen NM Pc 02876b; B – Scopeloides glarisianus dentary NM Pc 02888 (the white arrows mark the tips of the "fang-like" teeth); C – S. glarisianus disarticulated skeleton NM Pc 02887a; D – Sardinella sardinites scale NM Pc 02886; E – Clupeidae gen. et spec. indet. articulated skeleton without head NM Pc 02889; F – Anenchelum glarisianum body fragment NM Pc 02880a; G – Percoidei gen. et sp. indet. preoperculum (G-1) and its interpretation (G-2) NM Pc 02891. The arrow shows the enlarged spine in the angle between rami verticalis and horizontalis. Abbreviations: cl – cleithrum; op – operculum; pcl – postcleithrum.
Fig. 2 in Articulatae Distribution In Dobrudzha Coalfield, Bulgaria And Climatic Interpretation
Fig. 2 Distribution of the frequent Articulatae art in Dobrudzha Coalfield. Formation names abbreviation: Rak – Rakovski; Mo – Mogilishte; Vr – Vranino; MaB, MaC – Makedonka; Ve – Velkovo; Po – Polyantsi; Gut, Gub, Gut – Gurkovo. Mz – Mesozoic.
Text-fig. 2. Eospondylus primigenius (STÜRTZ) Bundenbach, Eschenbach-Bocksberg quarry, Lower Devonian, Lower Emsian (Zlichovian), Hunsrück Slate,, NM S 4764, x 3. Specimen with ventral arm coiling. The specimen is on its dorsum in slate with all five rays curled ventrally inward toward mouth area on underside of disk. Barely visible are tips of two jaws; slightly exposed are proximal parts of rays in oral view extending outward from disk. The location of abrupt ventral bending of rays is indicated by emergence from slate of five rays in aboral view that point inward toward buried disk. Based on ventral bending of rays and intimate association with crinoids Eospondylus has been interpreted as stratigraphic first occurrence of Order Euryalida, which contains epizoic gorgonocephalid and euryalid basket-stars of modern oceans. This status is rejected using new evidence from isolated vertebrae. [Photo by Alexander Glass]. in Isolated Ossicles Of The Family Eospondylidae Spencer Wright, 1966, In The Lower Devonian Of Bohemia (Czech Republic) And Correction Of The Systematic Position Of Eospondylid Brittlestars (Echinodermata: Ophiuroidea: Oegophiurida)
Text-fig. 2. Eospondylus primigenius (STÜRTZ) Bundenbach, Eschenbach-Bocksberg quarry, Lower Devonian, Lower Emsian (Zlichovian), Hunsrück Slate,, NM S 4764, x 3. Specimen with ventral arm coiling. The specimen is on its dorsum in slate with all five rays curled ventrally inward toward mouth area on underside of disk. Barely visible are tips of two jaws; slightly exposed are proximal parts of rays in oral view extending outward from disk. The location of abrupt ventral bending of rays is indicated by emergence from slate of five rays in aboral view that point inward toward buried disk. Based on ventral bending of rays and intimate association with crinoids Eospondylus has been interpreted as stratigraphic first occurrence of Order Euryalida, which contains epizoic gorgonocephalid and euryalid basket-stars of modern oceans. This status is rejected using new evidence from isolated vertebrae. [Photo by Alexander Glass].
Fig. 7 in Interpreting the condition of the forest environment with use of the SCP/MIB model of carabid communities (Coleoptera: Carabidae)
Fig. 7. The effect of fertilization, liming and soil acidification of the soil of the old coppices on Carabidae communities. Explanation of abbreviations please see in the text.
Fig. 4 in Interpreting the condition of the forest environment with use of the SCP/MIB model of carabid communities (Coleoptera: Carabidae)
Fig. 4. The effect of unevenaged forest stands fires on their Carabidae communities in Ostrow Mazowiecka
Fig. 5 in Interpreting the condition of the forest environment with use of the SCP/MIB model of carabid communities (Coleoptera: Carabidae)
Fig. 5. The effect of unevenaged forest stands fires on their Carabidae communities in Solec Kujawski
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.