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Dataset results
1,924 results for “knee osteoarthritis”
Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis
ClinicalTrials.gov study NCT04391842. IPD Sharing: NO. Countries: 1. Publications: 1.
Periosteal Stimulation for Knee Osteoarthritis
ClinicalTrials.gov study NCT00865046. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Tanezumab In Osteoarthritis Of The Knee (2)
ClinicalTrials.gov study NCT00830063. IPD Sharing: YES. Countries: 1. Publications: 3.
A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects
ClinicalTrials.gov study NCT02536833. IPD Sharing: NO. Countries: 1. Publications: 2.
Delaware Physical Exercise and Activity for Knee Osteoarthritis
ClinicalTrials.gov study NCT04980300. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Study to Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee
ClinicalTrials.gov study NCT04129944. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Participants With Knee Osteoarthritis
ClinicalTrials.gov study NCT03595618. IPD Sharing: Not stated. Countries: 1. Publications: 3.
STepped Exercise Program for Knee OsteoArthritis
ClinicalTrials.gov study NCT02653768. IPD Sharing: NO. Countries: 1. Publications: 6.
Study to Evaluate the Efficacy and Safety of EP-104IAR in Patients With Osteoarthritis of the Knee
ClinicalTrials.gov study NCT04120402. IPD Sharing: NO. Countries: 3. Publications: 1.
A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee
ClinicalTrials.gov study NCT00420992. IPD Sharing: Not stated. Countries: 1. Publications: 1.
AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee
ClinicalTrials.gov study NCT03182686. IPD Sharing: NO. Countries: 1. Publications: 1.
Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee.
ClinicalTrials.gov study NCT02709486. IPD Sharing: YES. Countries: 15. Publications: 16.
A Study of Duloxetine (LY248686) in Participants With Chronic Osteoarthritis and Knee Pain in Japan
ClinicalTrials.gov study NCT02248480. IPD Sharing: YES. Countries: 1. Publications: 7.
A Study Utilizing Patient-Reported and Radiographic Outcomes and Evaluating the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthriti
ClinicalTrials.gov study NCT03928184. IPD Sharing: NO. Countries: 1. Publications: 1.
Non-Surgical Management of Knee Osteoarthritis in the Military Health System (MHS)
ClinicalTrials.gov study NCT03747393. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
APSS-33-00: A Multicenter, Pilot Study of Autologous Protein Solution (APS) in Knee Osteoarthritis (OA)
ClinicalTrials.gov study NCT02138890. IPD Sharing: UNDECIDED. Countries: 4. Publications: 2.
Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Osteoarthritis (OA) of the Knee
ClinicalTrials.gov study NCT00878501. IPD Sharing: Not stated. Countries: 7. Publications: 1.
Assessment of cardiovascular risk factors in patients with Knee Osteoarthritis
Open the record for dataset details and reuse information.
Simultaneous bilateral unicompartmental knee replacement improves gait parameters in patients with bilateral knee osteoarthritis
<p>Background: Unicompartmental knee replacement (UKR) can provide reliable clinical and functional outcomes when performed simultaneously in both knees for treating bilateral osteoarthritis (OA). No studies to date have evaluated gait pattern after simultaneous bilateral UKR. The aim of this study was to evaluate changes in gait variables after bilateral single-stage UKR (B-UKR) and to compare them with the outcomes after unilateral UKR in two other groups of patients: one with bilateral knee OA (P-UKR) and one with the contralateral knee unaffected (H-UKR).<br> Methods: Three-dimensional motion cohort data were prospectively collected before and six months after surgery; 37 were allocated to the B-UKR (n =13), P-UKR (n= 12) or H-UKR (n = 12) group. Spatiotemporal variables (stride length, gait speed, gait cadence, stance phase, swing phase, and double support phase) and kinematic parameters (knee flexion and extension peak values, knee range of motion (ROM), and hip abduction peak value) were analyzed using mixed analysis of variance (ANOVA). The magnitude of effect for significant outcomes (ES) was determined using Cohen's d.<br> Results: Postoperative improvement in gait cadence (P b 0.01; ES=1.20), walking speed (P b 0.05; ES = 0.58), stride length (P b 0.05; ES = 0.67), knee ROM (P b 0.05; ES = 0.89), knee flexion (P b 0.05; ES=0.94), and hip abduction (P b 0.001; ES=1.16) was noted for the BUKR group, whereas only stride length improved (P b 0.05; ES=0.48) for the H-UKR group, and no changes in any gait parameter were seen for the P-UKR group.<br> Conclusions: Postoperative improvement in gait parameters was observed in the B-UKR patients with bilateral OA. Whenever possible, simultaneous bilateral UKR should be considered in such patients.</p>
Ultrasound data in knee osteoarthritis in a co0mmunity-based healthcare facility
<p><span><strong>Abstract:</strong> Diagnostic ultrasound (US) has been increasingly used in knee osteoarthritis (OA)</span><span>. This cross-sectional study performed between <span>January 2022 and June 2023</span> delves into the correlation between OMERACT (effusion synovitis, medial femoral condylar cartilage thickness, MFC, and osteophyte) and non-OMERACT (medial meniscal extrusion, MME and Baker’s cyst, BC) in knee OA. </span><span>Continuous (non-normal) data are presented as median (range) and categorical data are presented frequency (percentage). Inter-rater reliability of US data between raters performed using weighted Cohen’s kappa coefficient (r). Association between dichotomized US data has been assessed using the Chi-square test (<em>X<sup>2</sup></em>), p<0.05 was the level of statistical significance. 8</span><span>3 patients with a median age was 57 were enrolled consecuteively. 55 were female. 56 (67.5%) had unilateral and 27 (32.5%) had bilateral knee pain. Quadriceps muscle wasting was observed in 35 (42.7%) patients. Clinical signs (massage test, fluctuation test and cross fluctuation test) of effusion were revealed in 24 (28.9%). Radiological OA changes were depicted in 59 (71.1%) cases. US characteristics were detected in 80 individuals (96.3%), including BC, MME, effusion synovitis, MFC cartilage thickness change, and medial knee joint line osteophyte in 28 (35.9%), 37 (48.1%), 42 (51.8%), 62 (81.6%), and 63 (80.7%) patients, respectively. BC were seen in 28 (35.9%) cases and beak-shaped was the most common cyst type. OMERACT-MFC cartilage thickness and medial joint line osteophyte, were seen statistically correlated with non-OMERACT (MME and BC). Effusion synovitis was correlated significantly with MME (p<.001) but not with BC (p=.145). <span> </span></span></p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.