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507 results for “pneumococcal”
Safety, Tolerability, and Immunogenicity of a Polyvalent Pneumococcal Conjugate Vaccine (V116) in Japanese Adults (V116-002)
ClinicalTrials.gov study NCT04665050. IPD Sharing: YES. Countries: 1. Publications: 1.
The metabolic hormone adiponectin affects the correlation between nutritional status and pneumococcal vaccine response in vulnerable indigenous children
Open the record for dataset details and reuse information.
Data from: Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping.
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes. There are very few data on the concurrent carriage of multiple pneumococcal serotypes. This study aimed to identify the prevalence and serotype distribution of pneumococci carried in the nasopharynx of young healthy Nepalese children prior to the introduction of a pneumococcal conjugate vaccine using a microarray-based molecular serotyping method capable of detecting multi-serotype carriage. We conducted a cross-sectional study of healthy children aged 6 weeks to 24 months from the Kathmandu Valley, Nepal between May and October 2012. Nasopharyngeal swabs were frozen and subsequently plated on selective culture media. DNA extracts of plate sweeps of pneumococcal colonies from these cultures were analysed using a molecular serotyping microarray capable of detecting relative abundance of multiple pneumococcal serotypes. 600 children were enrolled into the study: 199 aged 6 weeks to <6 months, 202 aged 6 months to < 12 months, and 199 aged 12 month to 24 months. Typeable pneumococci were identified in 297/600 (49·5%) of samples with more than one serotype being found in 67/297 (20·2%) of these samples. The serotypes covered by the thirteen-valent pneumococcal conjugate vaccine were identified in 44·4% of samples containing typeable pneumococci. Application of a molecular serotyping approach to identification of multiple pneumococcal carriage demonstrates a substantial prevalence of co-colonisation. Continued surveillance utilising this approach following the introduction of routine use of pneumococcal conjugate vaccinates in infants will provide a more accurate understanding of vaccine efficacy against carriage and a better understanding of the dynamics of subsequent serotype and genotype replacement.
Obesity and the Receipt of Influenza and Pneumococcal Vaccination: a Systematic Review and Meta-analysis dataset
<p>Meta-analysis dataset from <strong>Obesity and the Receipt of Influenza and Pneumococcal Vaccination: a Systematic Review and Meta-analysis</strong>, in press at BMC Obesity</p>
Data from: Characterizing and comparing the seasonality of influenza-like illnesses and invasive pneumococcal diseases using seasonal waveforms
The seasonalities of influenza-like illnesses (ILIs) and invasive pneumococcal diseases (IPDs) remain incompletely understood. Experimental evidence indicates that influenza-virus infection predisposes to pneumococcal disease, so that a correspondence in the seasonal patterns of ILIs and IPDs might exist at the population level. We developed a method to characterize seasonality by means of easily interpretable summary statistics of seasonal shape—or seasonal waveforms. Non-linear mixed-effects models were used to estimate those waveforms based on weekly case reports of ILIs and IPDs in five regions spanning continental France from July 2000 to June 2014. We found high variability of ILI seasonality, with marked fluctuations of peak amplitudes and peak times, but a more conserved epidemic duration. In contrast, IPD seasonality was best modeled by a markedly regular seasonal baseline, punctuated by two winter peaks in late December–early January and January–February. Comparing ILI and IPD seasonal waveforms, we found indication of a small, positive correlation. Direct models regressing IPDs on ILIs provided comparable results, even though they estimated moderately larger associations. The method proposed is broadly applicable to diseases with unambiguous seasonality and is well-suited to analyze spatially or temporally grouped data, which are common in epidemiology.
A Study of Pneumococcal Conjugate Vaccine (V114) Compared to a Marketed Vaccine (V114-003)
ClinicalTrials.gov study NCT01215188. IPD Sharing: YES. Countries: 0. Publications: 1.
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers
ClinicalTrials.gov study NCT00714064. IPD Sharing: Not stated. Countries: 1. Publications: 3.
13 Valent Pneumococcal Conjugate Vaccine - Follow-on Study
ClinicalTrials.gov study NCT01095471. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Safety and Immunogenicity Following Meningococcal and Pneumococcal Immunization Among Adult People Living With HIV
ClinicalTrials.gov study NCT04875819. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea
ClinicalTrials.gov study NCT00219401. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Pneumococcal Adult-dose Ranging Immunization Study
ClinicalTrials.gov study NCT00169234. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effectiveness of the Pneumococcal Polysaccharide Vaccine in Military Recruits
ClinicalTrials.gov study NCT02079701. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Effects of Pneumococcal Vaccine on Nasopharyngeal Carriage
ClinicalTrials.gov study NCT01925222. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial
ClinicalTrials.gov study NCT05183854. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study Evaluating 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) In Healthy Infants In China
ClinicalTrials.gov study NCT01692886. IPD Sharing: Not stated. Countries: 1. Publications: 2.
PREVENTING PNEUMOcoccal Disease Through Vaccination (Study 2)
ClinicalTrials.gov study NCT04974294. IPD Sharing: NO. Countries: 1. Publications: 1.
Pneumococcal Vaccines Early and in Combination
ClinicalTrials.gov study NCT01174849. IPD Sharing: Not stated. Countries: 1. Publications: 15.
Pneumococcal Conjugate Vaccine Followup
ClinicalTrials.gov study NCT01414504. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy Trial of Two Pneumococcal Conjugate Vaccines (PncCRM and PncOMPC) for Prevention of Acute Otitis Media Due to Vaccine Serotypes
ClinicalTrials.gov study NCT00378417. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Offering Influenza and Pneumococcal Vaccine to Patients Being Evaluated in the Emergency Department
ClinicalTrials.gov study NCT00380679. IPD Sharing: Not stated. Countries: 1. Publications: 12.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.