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1,301 results for “retrospective study”
Blood cell differential count discretization modeling predicts survival in adults reporting to the emergency room: a retrospective cohort study
<p><strong>Objectives</strong>: to assess survival predictivity of baseline blood cell differential count (BCDC), discretized according to two different methods, in adults visiting the Emergency Room (ER) for illness or trauma over one-year. </p> <p><strong>Design</strong>: Retrospective cohort study of hospital records. </p> <p><strong>Setting</strong>: Tertiary care public hospital in northern Italy. </p> <p><strong>Participants</strong>: 11052 patients aged > 18 years, consecutively admitted to the ER in one year, and for whom BCDC collection was indicated by ER medical staff at first presentation.</p> <p><strong>Primary outcome</strong>: Survival was the referral outcome for explorative model development. Automated BCDC analysis at baseline assessed hemoglobin, red cell mean volume (MCV) and distribution-width (RDW), platelet distribution-width (PDW), plateletcrit (PCT), absolute red blood cells, white blood cells, neutrophils, lymphocytes, monocytes, eosinophils, basophils, and platelets. Discretization cutoffs were defined by Benchmark and Tailored methods. Benchmark cutoffs were stated on laboratory reference values (CLSI). Tailored cutoffs for linear, sigmoid-shaped and for U-shaped distributed variables were discretized by Maximally Selected Rank Statistics and by Optimal-Equal Hazard Ratio respectively. Explanatory variables (age, gender, ER admission during SARS-CoV2 surges, in-hospital admission) were analyzed using Cox multivariable regression. ROC curves were drawn by sum of Cox-significant variables for each method.</p> <p><strong>Results</strong>: Of 11052 patients (median age 67 years, IQR 51–81, 48% female), 59% (n=6489) were discharged and 41% (n=4563) were admitted in hospital. After a 306-day median follow up (IQR 208–417 days), 9455 (86%) patients were alive and 1597 (14%) deceased. Increased HRs were associated with age >73-years (HR=4.6 CI=4.0–5.2), in-hospital admission (HR=2.2 CI=1.9–2.4), ER admission during SARS-CoV2 surges (Wave-I HR=1.7 CI=1.5–1.9); Wave-II HR=1.2 CI=1.0–1.3). Gender, hemoglobin, MCV, RDW, PDW, neutrophils, lymphocytes and eosinophils counts were significant in overall. Benchmark-BCDC model included basophils and platelet count (AUROC 0.74). Tailored-BCDC model included monocyte counts and plateletcrit (AUROC 0.79).</p> <p><strong>Conclusions</strong>: baseline discretized BCDC provides meaningful insight regarding Emergency Room patients survival.</p>
All-ceramic Restorations: a Retrospective and Prospective Study
ClinicalTrials.gov study NCT07110220. IPD Sharing: NO. Countries: 1. Publications: 1.
A Retrospective Study to Evaluate the ConforMIS iUni, iDuo & iTotal® KRS
ClinicalTrials.gov study NCT03152357. IPD Sharing: NO. Countries: 1. Publications: 6.
Preoperative Anesthesia Automatic System:a Retrospective Cohort Study
ClinicalTrials.gov study NCT06148701. IPD Sharing: NO. Countries: 1. Publications: 1.
National Retrospective Study Of Recanalization Treatments In Pediatric Arterial Ischemic Stroke
ClinicalTrials.gov study NCT03887143. IPD Sharing: NO. Countries: 1. Publications: 2.
Retrospective Study on Prolonged Sedation Effects With Inhaled Agents in PICU
ClinicalTrials.gov study NCT05064592. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of a Modified Lip Repositioning Surgery Technique With Tie Levator Labii Superioris and Without Frenectomy and Myotomy for Treatment of Excessive Gingival Display: A Retrospective Study
ClinicalTrials.gov study NCT06944535. IPD Sharing: NO. Countries: 1. Publications: 1.
PMCF Retrospective Study Outcomes of a Premium Monofocal IOL
ClinicalTrials.gov study NCT04874376. IPD Sharing: NO. Countries: 1. Publications: 1.
A Retrospective Study on Multiple Classifier Endometrial Cancer
ClinicalTrials.gov study NCT05976113. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Observational Retrospective Cohort Study of Systemic Therapies for R/R DLBCL
ClinicalTrials.gov study NCT04697160. IPD Sharing: Not stated. Countries: 12. Publications: 2.
Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study
ClinicalTrials.gov study NCT07067892. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate
ClinicalTrials.gov study NCT05899751. IPD Sharing: Not stated. Countries: 3. Publications: 2.
Impact of Advanced Practical Nursing Intervention Versus Usual Care on Hypertension Control : Retrospective Study
ClinicalTrials.gov study NCT06227884. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Retrospective Study to Assess the Evolution of MRI or CT Lesions in Treated CNS Nocardiosis
ClinicalTrials.gov study NCT07013006. IPD Sharing: NO. Countries: 1. Publications: 2.
Evaluation of the Prevalence and Risk Factors for Patients With Peri-implant Disease：a Retrospective Study
ClinicalTrials.gov study NCT02662361. IPD Sharing: YES. Countries: 1. Publications: 1.
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
ClinicalTrials.gov study NCT04381611. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Influencing Factors in Patients With Colorectal and Gastric Polyps a Retrospective Study
ClinicalTrials.gov study NCT04444947. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Cabozantinib Real-life Use for Advanced Renal Cell Carcinoma in France: a Retrospective Descriptive Non-interventional Study of 2 Cohorts.
ClinicalTrials.gov study NCT03744585. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study.
ClinicalTrials.gov study NCT05806684. IPD Sharing: NO. Countries: 1. Publications: 15.
A Retrospective Real-world Study of Abemaciclib in HR+ Breast Cancer
ClinicalTrials.gov study NCT06341283. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.