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248 results for “rhythmicity”
Data from: Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity
<p>Animal circadian rhythms persist in constant darkness and are driven by intracellular transcription-translation feedback loops. Although these cellular oscillators communicate, isolated mammalian cellular clocks continue to tick away in darkness without intercellular communication. To investigate these issues in Drosophila, we assayed behavior as well as molecular rhythms within individual brain clock neurons while blocking communication within the ca. 150 neuron clock network. We also generated CRISPR-mediated neuron-specific circadian clock knockouts. The results point to two key clock neuron groups: loss of the clock within both regions but neither one alone has a strong behavioral phenotype in darkness; communication between these regions also contributes to circadian period determination. Under these dark conditions, the clock within one region persists without network communication. The clock within the famous PDF-expressing s-LNv neurons however was strongly dependent on network communication, likely because clock gene expression within these vulnerable sLNvs depends on neuronal firing or light</p>
Data from: Non-rhythmic head-direction cells in the parahippocampal region are not constrained by attractor network dynamics
Computational models postulate that HD cells are part of an attractor network integrating angular head turns. This network requires inputs from visual landmarks to anchor the HD signal to the external world. We investigated whether information about HD and visual landmarks is integrated in the medial entorhinal cortex and parasubiculum, resulting in neurons expressing a conjunctive code for HD and visual landmarks. We found that parahippocampal HD cells could be divided into two classes based on their theta-rhythmic activity: non-rhythmic and theta-rhythmic HD cells. Manipulations of the visual landmarks caused tuning curve alterations in most HD cells, with the largest visually driven changes observed in non-rhythmic HD cells. Importantly, the tuning modifications of non-rhythmic HD cells were often non-coherent across cells, refuting the notion that attractor-like dynamics control non-rhythmic HD cells. These findings reveal a new population of non-rhythmic HD cells whose malleable organization is controlled by visual landmarks.
Data from: The evolution of locomotor rhythmicity in tetrapods
Differences in rhythmicity (relative variance in cycle period) between mammal, fish, and lizard feeding systems have been hypothesized to be associated with differences in their sensorimotor control systems. We tested this hypothesis by examining whether the locomotion of tachymetabolic tetrapods (birds and mammals) is more rhythmic than that of bradymetabolic tetrapods (lizards, alligators, turtles, salamanders). Species averages of intra-individual coefficients of variation in cycle period were compared while controlling for gait and substrate. Variance in locomotor cycle periods is significantly lower in tachymetabolic than in bradymetabolic animals for data sets that include treadmill locomotion, non-treadmill locomotion, or both. When phylogenetic relationships are taken into account, the non-treadmill analysis and the pooled analyses remain significant, the treadmill analysis becomes nonsignificant (but only marginally). The co-occurrence of relatively high rhythmicity in both feeding and locomotor systems of tachymetabolic tetrapods suggests that the anatomical substrate of rhythmicity is in the motor control system, not in the musculoskeletal components.
The Use of Rhythmic Light Therapy in Mild Cognitive Impairment
ClinicalTrials.gov study NCT07318038. IPD Sharing: NO. Countries: 1. Publications: 0.
Multimodal Gait Training With and Without Rhythmic Auditory Stimulation in Chronic Stroke Patients
ClinicalTrials.gov study NCT06696950. IPD Sharing: NO. Countries: 1. Publications: 0.
Rhythmic Auditory Stimulation and Walking Performance in Multiple Sclerosis (MS) Patients
ClinicalTrials.gov study NCT01086371. IPD Sharing: Not stated. Countries: 1. Publications: 0.
RHYTHMIC STIMULUS EFFECTS ON NEURONAL OSCILLATORY ACTIVITY AND SPEACHES CAPABILITIES IN DEAF CHILDREN
ClinicalTrials.gov study NCT02901691. IPD Sharing: NO. Countries: 1. Publications: 0.
Rhythmical Massage Compared With Heart Rate Variability Biofeedback in Women With Menstrual Pain (Dysmenorrhea)
ClinicalTrials.gov study NCT03712800. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Use of Rhythmic Auditory Cueing During Bilateral Training of the Upper Extremities in Stroke Patients
ClinicalTrials.gov study NCT04939493. IPD Sharing: NO. Countries: 1. Publications: 0.
An EEG Study on the Rhythmic Nature of Perception and Attention
ClinicalTrials.gov study NCT06236399. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Training of the Rhythmic Skills With a Serious Game to Improve Gait and Cognitive Abilities in Parkinson's Disease
ClinicalTrials.gov study NCT02855710. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effects of a Single Session of Rhythmic Movement Program on Selected Biopsychological Parameters in PD Patients
ClinicalTrials.gov study NCT05973565. IPD Sharing: NO. Countries: 1. Publications: 0.
Circadian Rhythmicity During Coma Awakening
ClinicalTrials.gov study NCT06245434. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of the Effect of Rhythmic Sensory Stimulation on Fibromyalgia
ClinicalTrials.gov study NCT02493348. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Binaural Beat Technology and Rhythmical Photic Stimulation
ClinicalTrials.gov study NCT05666661. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Rhythmic Gymnastics Training in Children With Down Syndrome
ClinicalTrials.gov study NCT06284707. IPD Sharing: NO. Countries: 1. Publications: 0.
A Novel Multisensory-Rhythmic Intervention in Geriatric Rehabilitation
ClinicalTrials.gov study NCT06151626. IPD Sharing: NO. Countries: 1. Publications: 0.
Stabilizing Reversal and Rhythmic Stabilization vs Pelvic Proprioceptive Neuromuscular Facilitation in Stroke Patients
ClinicalTrials.gov study NCT06459388. IPD Sharing: NO. Countries: 1. Publications: 0.
Cognitive Benefit of Intensive Rehabilitation Using Rhythmic Music Training in Children With Complex Neurodevelopmental Disorder
ClinicalTrials.gov study NCT07303049. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation
ClinicalTrials.gov study NCT03453645. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.