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1,919 results for “trigger”
Microscopy images - " Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro"
<p>This repository contains microscopy data from the manuscript "Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro" by Aleksandar Sebastijanović, Laura Maria Azzurra Camassa, Vilhelm Malmborg, Slavko Kralj, Joakim Pagels, Ulla Vogel, Shan Zienolddiny-Narui, Iztok Urbančič, Tilen Koklič, and Janez Štrancar (published in Nanotoxicology, 18(4), 335–353. https://doi.org/10.1080/17435390.2024.2362367).</p> <p>Raw data are organized in folders named by image number, containing a subfolder with the date (year-day-month) of image acquisition. Followed by a subfolder named by a nanomaterial to which neurons were exposed. Each folder contains images from individual multi-channel, multi-position time-lapse experiments with different combinations of cells exposed to one nanomaterial. Files are named as: IMGxxxx_[ExperimentCode]_ROIxx_[Channel].tif, where each of the varying elements in [..] denotes the following:<br>• [ExperimentCode]: a short name of the experiment<br>• [Channel]: membrane (MEM), cytoplasm neuronal cells (NEU), nanomaterial (NANO), amyloid beta (AMY)</p>
SupplementaryData_A_helper_NLR_targets_organellar_membranes_to_trigger_immunity
<p>Supplementary data for "A_helper_NLR_targets_organellar_membranes_to_trigger_immunity" including:</p> <p>1.Phylogenetics analysis - Data S1 to 6) - Fig. 1A and S1</p> <p>2.AlphaFold3 Models - Data S7 - Fig. 1B and S2</p> <p>3.NRG1_delta14(Nb)_delta16(At) alignment - Data S8</p> <p>4.nrg1 KO plants genotyping (Data S9) - more details in Materials and Methods.</p> <p>5.HR_index_data - Data S10 - raw HR data presented in manuscript.</p> <p>6.Movie S1 - NRG1 puncta upon XopQ activation.</p>
Respiratory-triggered MRCP acquisition at 3T using a T2-weighted TSE (3D SPACE) sequence for Deep Learning-based reconstruction of MRCP
<h1>Description</h1> <p>This dataset is the sample data for MRCP_DLRecon (<a href="https://github.com/JinhoKim46/MRCP_DLRecon">GitHub</a>). <br>Place this dataset in the "Sample_data/" directory along with the "dataset.csv" file. </p> <h1>Data</h1> <p>The provided 3D MRCP data were acquired at 3T (Skyra, Siemens Healthineers AG, Erlangen) using the 3D-SPACE (3D T2w TSE) sequence for a single healthy volunteer. We provide two 2x and one 6x 3D MRCP data to ensure various training and testing scenarios. Each data in the HDF5 format contains the following structures:</p> <ul> <li>Datasets <ul> <li><strong>grappa</strong>: target data (y * x *<em> </em>slice)</li> <li><strong>kdata_raw</strong>: Raw <em>k</em>-space data (x2 or x6) (nCoil * PE * RO * slice)</li> <li><strong>kdata_fs</strong>: Fully-sampled k-space data from <strong>kdata_raw</strong> using GRAPPA (nCoil ×× PE ×× RO ×× Slice)</li> <li><strong>sm_espirit</strong>: ESPIRiT-based sensitivity maps (nCoil * y * x * slice)</li> </ul> </li> </ul> <h1>Citation</h1> <p>Please cite the following <a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/nbm.70002" target="_blank" rel="noopener">paper</a> if this dataset is helpful for your research :)</p> <blockquote> <p>Kim, J., Nickel, M. and Knoll, F. (2025), Deep Learning-Based Accelerated MR Cholangiopancreatography Without Fully-Sampled Data. NMR in Biomedicine, 38: e70002. https://doi.org/10.1002/nbm.70002 </p> </blockquote>
The 2021-2022 Fukushima-Oki Earthquakes in Northeastern Japan: Dehydration Triggered Fault Reactivation Boosted by Slab Segmentation
<p>codes.rar: codes of double-difference seismic tomography</p> <p>catalog.dat: earthquake phase catalog used in the DD tomography</p> <p>station.dat: station coordinates of the seismic network </p> <p>MOD: grids in the initial Vp and Vp/Vs models</p> <p>Vp_model.dat: inverted 3-D Vp model</p> <p>Vs_model.dat: inverted 3-D Vs model</p> <p>VpVs_model.dat: inverted 3-D Vp/Vs model</p> <p>earthquake.reloc: relocations of the earthquakes</p>
Water in peripheral TM-interfaces of Orai1-channels triggers pore opening
Open the record for dataset details and reuse information.
Data related to "Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27."
<p>Data used to generate figures, as well as all uncropped blots. Article abstract: "Maintenance of lysosomal integrity is essential for cell viability. Upon injury, lysosomes may be targeted for degradation via a selective form of autophagy known as lysophagy. The engulfment of a damaged lysosome by an autophagosome is mediated by the recruitment of adaptor proteins, including SQSTM1/p62. p62 promotes lysophagy via the formation of phase separated condensates in a mechanism that is regulated by the heat shock protein HSP27. Here, we demonstrate a direct interaction between HSP27 and p62. We used structural modeling to predict the binding interface between HSP27 and p62 and identify several disease-associated mutations that map to this interface. We used proteomics to identify post-translational modifications of HSP27 that regulate HSP27 recruitment to stressed lysosomes, finding robust phosphorylation at several serine residues. Next, we characterized the upstream signaling mechanism leading to HSP27 phosphorylation, and found that p38 MAPK and its effector kinase MK2 are activated upon lysosomal damage by the kinase mTOR and the production of intracellular reactive oxygen species (ROS). Increased ROS activates p38 MAPK, which in turn allows MK2-dependent phosphorylation of HSP27. Depletion of HSP27 or the inhibition of HSP27 phosphorylation alters the dynamics of p62 condensates on stressed lysosomes, significantly inhibiting p62-dependent lysophagy. Thus, we define a novel lysosomal quality control mechanism in which lysosomal injury triggers a p38 MAPK/MK2 signaling cascade promoting p62-dependent lysophagy. Further, this signaling cascade is activated by many cellular stressors, including oxidative and heat stress, suggesting that other forms of selective autophagy may be regulated by p38 MAPK/MK2/HSP27." </p>
Progressive failure analysis of slip zone soils with strain-softening behavior and implications for landslide triggering mechanisms
<p>All figure for paper entitled “Progressive failure analysis of slip zone soils with strain-softening behavior and implications for landslide triggering mechanisms”</p>
Dataset of "Triggering and propagation of exogeneous sediment pulses in mountain channels: insights from flume experiments with seismic monitoring"
<p>Dataset of "Triggering and propagation of exogeneous sediment pulses in mountain channels: insights from flume experiments with seismic monitoring".</p>
Remote Sensing of Radiation Belt Energetic Electrons Using Lightning Triggered Upper Band Chorus
<p>We report very low frequency (VLF) observation of interaction of waves from atmospheric lightning with radiation belt particles. The observation provides a unique opportunity to remotely sense the dynamics of the energetic particle population in the Earth’s radiation belts and how this population leads to amplification and generation of waves.</p>
Data for: Causal mechanisms for negative impacts of energy development inform management triggers for sagebrush birds
<p>Estimated population trends can identify declining species to focus biological conservation, but monitoring may fail to illuminate causes of population change and strategies for reversing declines. Monitoring programs can relate trends with environmental attributes to test causal hypotheses, but typical analytical approaches do not explicitly support causal inference, diluting available data for informing conservation. The U.S. Bureau of Land Management (BLM) extended Integrated Monitoring in Bird Conservation Regions with a quasi-experimental sampling design over a 10-year period (2010–2019) to evaluate impacts of oil and gas development on sagebrush birds within the Atlantic Rim Natural Gas Development Project in southern Wyoming. We analyzed resulting data using a multi-scale community occupancy model to estimate trends in species occupancy and richness relevant to management triggers. Additionally, we employed path analysis to evaluate mechanisms underlying observed trends to inform potential management responses. Fine-scale occupancy for sage thrasher (<em>Oreoscoptes montanus</em>) declined within the high-development stratum at a rate sufficient to meet an<em> a priori</em> management trigger established by the BLM. Two additional sagebrush-associated species, Brewer's (<em>Spizella breweri</em>) and sagebrush sparrow (<em>Artemisiospiza nevadensis</em>), exhibited negative development relationships with trend, as did overall species richness, and richness of grassland, sagebrush, and generalist guilds. We identified well pad density and invasive plants associated with energy development as causal factors contributing to these negative development impacts. We demonstrate an analytical approach for both estimating occupancy trends and identifying underlying causes to inform conservation action. Reducing the development footprint, including well pad density and associated invasive plants, could help reduce or limit impacts on birds within this landscape.</p>
Feeding on a Bartonella henselae infected host triggers temporary changes in the Ctenocephalides felis microbiome
<p>The effect of <em>Bartonella</em> <em>henselae</em> on the microbiome of its vector, <em>Ctenocephalides</em> <em>felis</em> (the cat flea) is largely unknown, as a majority of <em>C. felis</em> microbiome studies have utilized wild-caught pooled fleas. Therefore, we surveyed the microbiome of laboratory-origin <em>C. felis</em> fed on <em>B. henselae-</em>infected cats to identify changes to microbiome diversity and microbe prevalence compared to unfed fleas, and fleas fed on uninfected cats. To evaluate changes over time, fleas were fed on cats for 24 hours or 9 days. Utilizing Next Generation Sequencing (NGS) on the Illumina platform, we documented an increase in microbial diversity, richness, and evenness in <em>C. felis</em> fed on <em>Bartonella</em>-infected cats for 24 hours, changes that returned to baseline (unfed fleas or fleas fed on uninfected cats) after 9 days on the host. The increased diversity in the <em>C. felis</em> microbiome when fed on <em>B. henselae</em>-infected cats may be related to the mammalian, flea, or endosymbiont response, factors that remain to be explored and potentially exploited for pathogen control. In addition, poor <em>B</em>. <em>henselae</em> acquisition was documented in these laboratory-maintained <em>C. felis</em>. Potential hypotheses to account for this finding include poor acquisition by adult fleas, the influence of flea genetic variation on <em>B. henselae</em> acquisition, and lack of co-feeding with <em>B. henselae</em>-infected <em>C. felis</em>. This study provides an investigation of the <em>C. felis</em> microbiome response to blood feeding and blood-feeding on <em>B. henselae</em>-infected cats; however, future studies are necessary to fully characterize the effect of endosymbionts and <em>C. felis</em> diversity on <em>B. henselae</em> acquisition.</p>
Data for the article "Emission of coherent THz magnons in an antiferromagnetic insulator triggered by ultrafast spin-phonon interactions "
<p>Data for the article "Emission of coherent THz magnons in an antiferromagnetic insulator triggered by ultrafast spin-phonon interactions" </p> <p>URL: https://arxiv.org/abs/2205.11965<br> DOI: In press in Nature Communications</p>
Data Availibility for "Susceptibility of microseismic triggering to small sinusoidal stress perturbations at the laboratory scale"
<p>List of data contained within this repository.</p> <p>Total weight = ~ 40GB</p> <p>--- Raw data :</p> <p> </p> <p>-For all experiments (control and oscillation experiments):</p> <p>Mechanical data files (460 MB);<br> Acoustic emission waveforms (40 GB).</p> <p>--- Derived data:</p> <p> </p> <p>-For the control experiment:</p> <p>RSFit3000 Rate and State parameters (30 MB);</p> <p> </p> <p>-For oscillation experiments:</p> <p>RMS magnitudes of acoustic emissions ; (1 MB)<br> Phase of arrival of acoustic emissions (500 KB);<br> Response amplitudes of fused and unfused steps (1 KB);<br> Susceptibility to Pc oscillation amplitude (1 KB);<br> b-values as a function of stress oscillation phase (100 KB).</p>
Extended figures: Tumour immune rejection triggered by activation of alpha2-adrenergic receptors
<p>Code and data to reproduce the extended figures from Tumour immune rejection triggered by activation of alpha2-adrenergic receptors by Zhu et al. </p>
Data for: Fishing triggers trophic cascade in terms of variation, not abundance, in an allometric trophic network model
<p>Trophic cascade studies often rely on linear food chains instead of complex food webs and are typically measured as biomass averages, not as biomass variation. We study trophic cascades propagating across a complex food web including a measure of biomass variation in addition to biomass average. We examined whether different fishing strategies induce trophic cascades and whether the cascades differ from each other. We utilized an allometric trophic network (ATN) model to mechanistically study fishing-induced changes in food web dynamics. Different fishing strategies did not trigger traditional, reciprocal trophic cascades, as measured in biomass averages. Instead, fishing triggered a variation cascade that propagated across the food web, including fish, zooplankton and phytoplankton species. In fisheries that removed a large amount of top-predatory and cannibalistic fish, the biomass oscillations started to decrease after fishing was started. In fisheries that mainly targeted large planktivorous fish, the biomass oscillations did not dampen but slightly increased over time. Removing species with specific ecological functions might alter the food web dynamics and potentially affect the ecological resilience of aquatic ecosystems.</p>
Data from: Triggered Golgi membrane enrichment promotes PtdIns(4,5)P2 generation for plasma membrane repair
<p><span>The maintenance of plasma membrane integrity and a capacity for efficiently repairing damaged membranes are essential for cell survival. Large-scale wounding depletes various membrane components at the wound sites, including phosphatidylinositols, yet little is known about how phosphatidylinositols are generated after depletion. Here, working with our <em>in</em> <em>vivo C. elegans</em> epidermal cell wounding model, we discovered phosphatidylinositol 4-phosphate (PtdIns4<em>P</em>) accumulation and local phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)<em>P<sub>2</sub></em>] generation at the wound site. We found that PtdIns(4,5)<em>P<sub>2</sub></em> generation depends on the delivery of PtdIns4<em>P</em>, PI4K, and PI4P 5-kinase PPK-1. In addition, we show that wounding triggers enrichment of the Golgi membrane to the wound site, and that is required for membrane repair. Moreover, genetic and pharmacological inhibitor experiments support that the Golgi membrane provides the PtdIns4<em>P</em> for PtdIns(4,5)<em>P<sub>2</sub></em> generation at the wounds. Our findings demonstrate how the Golgi apparatus facilitates membrane repair in response to wounding and offers a valuable perspective on cellular survival mechanisms upon mechanical stress in a physiological context. </span></p>
Molecular in situ monitoring of the pH-triggered response in adaptive polymers by two-dimensional Raman micro-correlation-spectroscopy - Raw Data
<p>Raw data for publication Molecular in situ monitoring of the pH-triggered response in adaptive polymers by two-dimensional Raman micro-correlation-spectroscopy</p>
Strong HONO Emissions from Dew and Guttation Evaporation Trigger Severe Photochemical Pollution Formation
<p>Data for the manuscript "Strong HONO Emissions from Dew and Guttation Evaporation Trigger Severe Photochemical Pollution Formation" by Xu et al.</p>
Table 3 for the Study: "Correlation Study: Triggering and Magnitude of Earthquakes in Italy (≥M4.3) in Relation to the Positions and Gravitational Forces of the Sun, Moon, and Planets Relative to Earth."
<p><strong>Study of σFR gravitational forces exerted by the angular distances of all 9 S.S. celestial bodies toward Earth: L'Aquila Earthquake, 06.04.2009, Italy, M6.1 for Section 2.9.</strong></p><p>In case of display problems or missing data, the file <a href="https://zenodo.org/api/files/30eebe1b-d3a1-406a-975c-23ad8abe143f/Table_3_FR_L'Aquila_2009.xlsx?versionId=c778a73b-60c6-4504-a178-8edb1471e98c">Table_3_FR_L'Aquila_2009.xlsx</a> on Drive available for consultation is this one: <a href="https://docs.google.com/spreadsheets/d/1QteARypgGETNkbLB_O0VNWfmrYa0saFWvX0z1EacDEo/edit?usp=sharing">https://docs.google.com/spreadsheets/d/1QteARypgGETNkbLB_O0VNWfmrYa0saFWvX0z1EacDEo/edit?usp=sharing</a></p><p>The URL of the Calculation Excel sheet that allows calculation of the resulting gravitational force σFR in the month of the 2009 L'Aquila earthquake, M6.1 (n. 85), in the study <i>"</i>Correlation Study: Triggering and Magnitude of Earthquakes in Italy (≥M4.3) in Relation to the Positions and Gravitational Forces of the Sun, Moon, and Planets Relative to Earth<i>", </i>Section 2.9.</p>
Table 8 for the Study: "Observation of correlation between earthquake triggering of M>4.3 and specific Sun-Moon-Planets positions in the Solar System, from 1600 in Italy."
<p><strong>Graphs of the data distributions, with the R<sup>2</sup> regression values of σFR and the corresponding functions.</strong></p> <p>In case of display problems or missing data, the file <a href="https://zenodo.org/api/files/305630bd-70bd-4347-99eb-bfd6fb3af726/Table%208_SFR_distributions_curves.xlsx">Table 8_SFR_distributions_curves.xlsx</a> on Drive available for consultation is this one: <a href="https://docs.google.com/spreadsheets/d/17UGHZlvZ2N-g6TOzgqpIe248_IitBmka8DbGWsv-lKQ/edit?usp=sharing">https://docs.google.com/spreadsheets/d/17UGHZlvZ2N-g6TOzgqpIe248_IitBmka8DbGWsv-lKQ/edit?usp=sharing</a> </p> <p>URL of the plots of the data distributions, with the <strong>R<sup>2</sup></strong> regression values of σFR at the time of the triggering of the 200 earthquakes analyzed in the paper <em>"Observation of correlation between earthquake triggering of M>4.3 and specific Sun-Moon-Planets positions in the Solar System, from 1600 in Italy", paragraph </em><strong>3.02.</strong></p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.