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2,009 results for “Disruption”

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geo20/100

Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to a variety of infectious agents [primary T and B cells]

GEO Series GSE166872. Homo sapiens. 57 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2021View details →
geo20/100

Digenome for off-target analysis: Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy

GEO Series GSE146997. Homo sapiens. 2 samples. Type: Other.

openGEO-OpenSep 2020View details →
geo20/100

Human Respiratory Syncytial Virus Non-Structural Protein NS1 enters the nucleus to disrupt gene transcription (ChIP-seq)

GEO Series GSE155150. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenOct 2021View details →
geo20/100

Sam68-mediated disruption of CBP/β-catenin neoplastic transcriptional programming allows selective targeting of human cancer stem cells

GEO Series GSE34965. Homo sapiens. 4 samples. Type: Expression profiling by array.

openGEO-OpenOct 2017View details →
geo20/100

Heterogeneous Cardiac- and Neural Crest-Derived Aortic Smooth Muscle Cells have Similar Transcriptional Changes after TGFβ Signaling Disruption [Bulk-RNA-seq-of-Human-aortas]

GEO Series GSE253932. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo20/100

Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons

GEO Series GSE62632. Homo sapiens. 35 samples. Type: Expression profiling by array.

openGEO-OpenOct 2014View details →
geo20/100

Small molecule RBI2 disrupts ribosome biogenesis through pre-rRNA depletion

GEO Series GSE188262. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo20/100

Single-Cell multi-omics reveals disrupted gene regulatory landscape and cell differentiation by Wilms tumor-associated ENL mutation in the developing kidney (ChIP-Seq)

GEO Series GSE243866. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo20/100

Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1 [RNA-seq]

GEO Series GSE218283. Mus musculus. 59 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2022View details →
geo20/100

SMARCA4-mutant lung cancer disrupts anti-tumor immunity and immunotherapy response in a STING pathway-dependent manner II

GEO Series GSE269686. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo20/100

Disruption of the Transcriptional Regulator Cas5 Results in Enhanced Killing of Candida albicans by Fluconazole

GEO Series GSE57930. Candida albicans. 8 samples. Type: Expression profiling by array.

openGEO-OpenMay 2014View details →
geo20/100

Disrupted minor intron splicing activates reductive carboxylation-mediated lipogenesis to drive metabolic dysfunction–associated steatotic liver disease progression

GEO Series GSE272322. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo20/100

Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity

GEO Series GSE153973. Homo sapiens. 90 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.

openGEO-OpenFeb 2021View details →
geo20/100

CEBPA Dysfunction Intiates CSF3R Mutant Acute Myeloid Leukemia Through Disruption of Myeloid Lineage Enhancers (ChIP-seq)

GEO Series GSE122162. Mus musculus. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2019View details →
geo20/100

Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer

GEO Series GSE194097. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2022View details →
geo20/100

Influenza virus-induced type I interferons disrupt alveolar epithelial repair and tight junction integrity in the developing lung

GEO Series GSE287098. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo20/100

Domain-specific mutations in dyskerin disrupt 3´end processing of snoRNAs

GEO Series GSE190173. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo20/100

Imbalance in Unc80 RNA Editing Disrupts Dynamic Neuronal Activity and Olfactory Perception

GEO Series GSE269152. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo20/100

Aurora B and INCENP co-overexpression severely disrupts mitosis and distinctly modifies the global transcriptional landscape [RNA-seq]

GEO Series GSE273663. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2025View details →
geo20/100

Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

GEO Series GSE9241. Homo sapiens. 17 samples. Type: Expression profiling by array.

openGEO-OpenOct 2007View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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