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2,009 results for “Disruption”

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geo20/100

EC-8042 disrupts both the primary SP/KLF transcription regulatory network and the secondary network induced by HDACi treatment. [SP1&H3K27me3 CUT&Tag]

GEO Series GSE268110. Homo sapiens. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo20/100

Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells [ChIP-seq]

GEO Series GSE158794. Homo sapiens. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2021View details →
geo20/100

Activation of proto-oncogenes by disruption of chromosome neighborhoods [RNA-Seq]

GEO Series GSE68975. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2015View details →
geo20/100

Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis

GEO Series GSE190938. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2023View details →
geo20/100

Deletion of thioredoxin reductase disrupts redox homeostasis and impairs β-cell function

GEO Series GSE200965. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo20/100

Disruption of CSF-1R signaling affects cerebellar and forebrain homeostasis

GEO Series GSE133362. Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2019View details →
geo20/100

Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation [ChIP-Seq 1]

GEO Series GSE205836. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
geo20/100

Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β-cell function [ATACseq]

GEO Series GSE182936. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo20/100

Disruption of Y chromosome expression in male lung cancer

GEO Series GSE151103. Homo sapiens. 360 samples. Type: Expression profiling by array.

openGEO-OpenJun 2021View details →
geo20/100

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [DRIP-seq]

GEO Series GSE226001. Homo sapiens. 4 samples. Type: Other.

openGEO-OpenMar 2024View details →
geo20/100

Transcriptional heterogeneity overcomes super-enhancer disrupting drug combinations in multiple myeloma

GEO Series GSE244003. Homo sapiens. 44 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →
geo20/100

Pharmacologic disruption of agr quorum sensing in Staphylococcus aureus promotes host defense against skin and soft tissue infections

GEO Series GSE52978. Staphylococcus aureus subsp. aureus USA300; Staphylococcus aureus. 12 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2017View details →
geo20/100

E2F1 methylation by SETD6 disrupts BRD4-E2F1 binding and modulates gene regulation in prostate cancer cells

GEO Series GSE286198. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo20/100

Folate Pathway Disruption Leads to Critical Depletion of Methionine Derivatives in Mycobacterium tuberculosis

GEO Series GSE55979. Mycobacterium tuberculosis H37Rv. 12 samples. Type: Expression profiling by array.

openGEO-OpenMar 2014View details →
geo20/100

INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly

GEO Series GSE154197. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2021View details →
geo20/100

Maternal High Fat Diet and Diabetes Disrupts Transcriptomic Pathways that Regulate Cardiac Metabolism and Cell Fate in Newborn Rat Hearts

GEO Series GSE150649. Rattus norvegicus. 23 samples. Type: Expression profiling by array.

openGEO-OpenSep 2020View details →
geo20/100

Microarray studies of pqqE disruption mutant vs wild type

GEO Series GSE17724. Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539; Deinococcus radiodurans. 2 samples. Type: Expression profiling by array.

openGEO-OpenAug 2009View details →
geo20/100

Dioxin Disrupts Dynamic DNA Methylation Patterns in Genes that Govern Cardiomyocyte Maturation

GEO Series GSE154599. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.

openGEO-OpenJul 2020View details →
geo20/100

Cancer-induced FOXP1 disrupts and reprograms skeletal muscle circadian transcription in cachexia [ChIP-seq]

GEO Series GSE273712. Mus musculus. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2025View details →
geo20/100

Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface

GEO Series GSE7835. Homo sapiens. 15 samples. Type: Expression profiling by array.

openGEO-OpenMay 2007View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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