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1,574
datasets available to search
ShareScore release 0.9.0
Dataset results
1,574 results for “genome sequencing”
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type, genome-edited MTOR(G4448A)-p.C1483Y, and Torin1-treated Wild type Translatomics
GEO Series GSE129816. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
Whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat, at different sequencing depths (Affymetrix exon-level)
GEO Series GSE53860. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
The specific DNA sequence recognized by the yeast transcription factor Gcn4 is sufficient to predict high-affinity binding on a genome-wide scale
GEO Series GSE180114. Saccharomyces cerevisiae. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Common DNA sequence variation influences 3-dimensional conformation of the human genome
GEO Series GSE128678. Homo sapiens. 38 samples. Type: Other; Third-party reanalysis.
Widespread RNA and DNA Sequence Differences in the Human Genome
GEO Series GSE25840. Homo sapiens. 0 samples. Type: Third-party reanalysis; Expression profiling by high throughput sequencing.
RNA sequencing analysis of the whole genome expression profile in non-thermal atmospheric pressure plasma (NTAPP)-exposed and -unexposed human adipose tissue-derived stem cells (ASCs)
GEO Series GSE131386. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide identification of micro-ribonucleic acids associated with human endometrial receptivity in natural and stimulated cycles by deep sequencing
GEO Series GSE26516. Homo sapiens. 4 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Whole genome bisulfite sequencing of adult opossum tissues
GEO Series GSE206392. Monodelphis domestica. 18 samples. Type: Methylation profiling by high throughput sequencing.
Whole genome sequencing of Drosophila melanogaster from different microclimates at 'Evolution Canyon'
GEO Series GSE104077. Drosophila melanogaster. 32 samples. Type: Other.
Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis
GEO Series GSE213717. Mus musculus. 12 samples. Type: Methylation profiling by array.
Draft genome sequence of Klebsiella quasipneumoniae subsp. similipneumoniae strain IF3SW-P1 isolated from the International Space Station
In 2015, the Advanced Resistive Exercise Device (ARED) foot panel on the International Space Station (ISS) was sampled to identify culturable microorganisms. The whole-genome of the strain IF3SW-P1 was sequenced using the Oxford Nanopore Technologies platform and identified as Klebsiella quasipneumoniae subsp. quasipneuomoniae, a Biosafety Level-2 (BSL-2) human pathogen. This whole-genome sequence will aid in comparative genomic analyses with Earth-origin pathogens for differences in virulence and antimicrobial resistance in microorganisms exposed to spaceflight conditions.
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface, Kirovograd region soil, Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline sequences will help to understand the observed production of novel bioactive compounds.
Draft Genome Sequence of Solibacillus kalamii, Isolated from an Air Filter Aboard the International Space Station
Solibacillus kalamii was isolated from a HEPA filter in the International Space Station. This strain was of particular interest due to the unique environment in which it was isolated from.
Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station
Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground control, after direct exposure to space conditions onboard the International Space Station (ISS) for 1.5 years. The resulting ISS-flown and non-flown strains were sequenced using the Nanopore MinION and an in-house method and pipeline to identify methylated positions in the genome. Our analysis indicated genomic variants and m6A methylation increased in the ISS-flown SAFR-032. To complement the broader omics investigation and explore phenotypic changes, ISS-flown and non-flown strains were compared in a series of laboratory-based chamber experiments using an X-ray irradiation source (doses applied at 250, 500, 750, 1000 and 1250 Gy); results show a potentially higher survival fraction of ISS-flown DS2 at the two highest exposures. Taken together, results from this study document lasting changes to the genome by methylation, potentially triggered by conditions in spaceflight, with functional consequences for the resistance of bacteria to stressors expected on long-duration missions beyond low Earth orbit.
Draft genome sequences of Aspergillus and Penicillium species isolated from the International Space Station and Crew Resupply Vehicle Capsule
Genome sequencing and assembly of fungal isolates belonging to Penicilliium and Aspergillus genera isolated from International Space Station
Microbial Observatory (ISS-MO): Draft Genome Sequence of two Aspergillus fumigatus Strains Isolated from the International Space Station
Aspergillus fumigatus is a saprophytic, filamentous fungus that is ubiquitous outdoors (soil, decaying vegetation) and indoors (hospitals, simulated closed habitats, etc.). A. fumigatus can adapt to various environmental conditions and form airborne conidia that are the inoculum for a variety of diseases (e.g. non- and invasive pulmonary infections, allergic bronchopulmonary aspergillosis, etc.) in immunocompromised hosts. In an on-going Microbial Observatory Experiments on the International Space Station (ISS) molecular phylogeny of several fungal isolates were characterized. Two strains, ISSF 21 and IF1SW-F4, were isolated from the HEPA filter and the surface of the Cupola of the ISS, respectively. Using primers targeting the internal transcribed spacers ITS1 and 2, both isolates were identified as A. fumigatus. The whole genome sequence analysis of ISSF 21 revealed increased number of single nucleotide polymorphisms (SNPs) when compared to the reference A. fumigatus 293. Knowing that A. fumigatus is an opportunistic pathogen and microgravity highly influences the antibiotic susceptibility and pathogenicity of microorganisms, we examined pathogenicity of both ISS isolates using the zebrafish larval model. The space station isolates (ISSF-021 and IF1SW-F4) were more virulent than two clinical strains (Af293 and CEA10) whose pathogenicity was highly characterized. Here the whole genome sequences of ISSF-021 strain are being deposited.
Draft Genome Sequences of Two Fusarium oxysporum Isolates Cultured from Infected Zinnia hybrida Plants Grown on the International Space Station
Draft genome sequences of two Fusarium oxysporum isolates cultured from infected Zinnia hybrida plants grown on the International Space Station
Draft Genome Sequences of novel Agrobacterium genomospecies 3 Associated from the International Space Station
The whole-genome sequences (WGS) of three pathogenic bacterial strains collected from the International Space Station (ISS) were generated and identified as being part of Class Alphaproteobacteria. The WGS studies would enable further genomic/biochemical characterization of taxa for these bacteria that have been subjected to the microgravity conditions of space.
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface Kirovograd region soil Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline sequences will help to understand the observed production of novel bioactive compounds.
Draft Genome Sequences of Members of the family Methylobacteriaceae Associated with the International Space Station
Draft Genome Sequences of isolates belonging to family Methylobacteriaceae Isolated from the International Space Station
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.