Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Combined systemic disruption of MET and EGFR signaling causes liver failure in normal mice
GEO Series GSE116307. Mus musculus. 4 samples. Type: Expression profiling by array.
Selective miRNA disruption in Tregs leads to uncontrolled autoimmunity
GEO Series GSE11818. Mus musculus. 6 samples. Type: Expression profiling by array.
Slc7a7 disruption causes fetal growth retardation by down-regulating Igf1 in the mouse model of LPI
GEO Series GSE5432. Mus musculus. 8 samples. Type: Expression profiling by array.
Disruption of SUV39H1-mediated H3K9 methylation sustains CAR T cell function [scRNA/CITE-seq]
GEO Series GSE246960. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing; Other.
Targeting the chromatin-binding of XPO1 disrupts NFAT and T cell activation
GEO Series GSE228212. Homo sapiens. 114 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
HDAC6 Inhibition Disrupts HDAC6-P300 Interaction Reshaping the Cancer Chromatin Landscape (ATAC-Seq)
GEO Series GSE273644. Homo sapiens; Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Prenatal Bisphenol A Exposure in Mice Induces Multi-tissue Multi-omics Disruptions Linking to Cardiometabolic Disorders (RNA-Seq)
GEO Series GSE121603. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Disruptions of Topological Chromatin Domains Causes Pathogenic Rewiring of Gene-Enhancer Interactions
GEO Series GSE66383. Homo sapiens; Mus musculus. 31 samples. Type: Expression profiling by high throughput sequencing; Other.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [Ser2PRNAPII ChIP-seq]
GEO Series GSE225995. Homo sapiens. 29 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disrupting the adult-globin promoter alleviates promoter competition and reactivates foetal-globin gene expression
GEO Series GSE194064. Homo sapiens. 6 samples. Type: Other.
Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity [ChIPmentation]
GEO Series GSE153971. Homo sapiens. 30 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A Stat1 gain-of-function mutant disrupts normal Stat4 innate lymphocyte programs during viral infection [CUT&Tag]
GEO Series GSE284322. Mus musculus. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruptions of Topological Chromatin Domains Causes Pathogenic Rewiring of Gene-Enhancer Interactions [RNA-Seq]
GEO Series GSE66377. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Disruption of gul-1 decreased the culture viscosity and improved protein secretion in the filamentous fungus Neurospora crassa
GEO Series GSE113321. Neurospora crassa. 2 samples. Type: Expression profiling by high throughput sequencing.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [Ser5PRNAPII ChIP-Seq]
GEO Series GSE254791. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption in A-to-I editing levels affects C. elegans development more than a complete lack of editing
GEO Series GSE110701. Caenorhabditis elegans. 42 samples. Type: Expression profiling by high throughput sequencing; Other.
A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome (RNA-Seq)
GEO Series GSE132836. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.
Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses
GEO Series GSE122798. Macaca mulatta. 26 samples. Type: Expression profiling by array.
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma [SYATAC_ATAC-seq]
GEO Series GSE266134. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Liver gene expression response to circadian rhythm disruption
GEO Series GSE65346. Mus musculus. 120 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.