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1,444 results for “Mitigation”
Salidroside Mitigates Oligoasthenospermia by Attenuating Ferroptosis-mediated Lipid Peroxidation via NF-κB Pathway Inhibition
GEO Series GSE249162. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Beta vulgaris-Derived Exosome-like Nanovesicles Mitigate Photoaging by Attenuating Oxidative Stress and Promoting Collagen Biosynthesis Abstract
GEO Series GSE310833. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of cytosolic translation mitigates mitochondrial dysfunction in C. elegans
GEO Series GSE290561. Caenorhabditis elegans. 11 samples. Type: Expression profiling by high throughput sequencing.
Targeting sulfation-dependent mechanoreciprocity between matrix and osteoblasts to mitigate bone loss
GEO Series GSE232923. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Integrated analysis of physiology, transcriptomics and metabonomics revealed the mechanisms of high pH mitigating copper toxicity in Citrus sinensis roots
GEO Series GSE225124. Citrus sinensis. 12 samples. Type: Expression profiling by high throughput sequencing.
CBF-beta mitigates PI3K-alpha specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
GEO Series GSE235631. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Codonopsis pilosula polysaccharides mitigates Brucella abortus outer membrane protein 19-induced uterine damage via macrophage adhesion and calcium signaling
GEO Series GSE314097. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Histone methyltransferase Setd2 mitigates T cell-mediated autoimmunity by targeting Lpcat4-mediated phospholipid remodeling
GEO Series GSE235827. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Lactate deficiency-induced early embryonic arrest is mitigated through malate-aspartate shuttle
GEO Series GSE299062. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Clinical Pilates and Prenatal Education: A Prospective Cohort Study on Mitigating Postpartum Depression and Improving Maternal Outcomes
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A Polyphenol-Rich Extract of Olive Mill Wastewater Enhances Cancer Chemotherapy Effects, While Mitigating Cardiac Toxicity
<p>Cardiovascular toxicity remains one of the most adverse side effects in cancer patients receiving chemotherapy. Extra-virgin olive oil (EVOO) is rich in cancer preventive polyphenols endowed with anti-inflammatory, anti-oxidant activities which could exert protective effects on heart cells. One very interesting derivative of EVOO preparation is represented by purified extracts from olive mill waste waters (OMWW) rich in polyphenols. Here, we have investigated the anti-cancer activity of a OMWW preparation, named A009, when combined with chemotherapeutics, as well as its potential cardioprotective activities. Mice bearing prostate cancer (PCa) xenografts were treated with cisplatin, alone or in combination with A009. In an <em>in vivo</em> model, we found synergisms of A009 and cisplatin in reduction of prostate cancer tumor weight. Hearts of mice were analyzed, and the mitochondria were studied by transmission electron microscopy. The hearts of mice co-treated with A009 extracts along with cisplatin had reduced mitochondria damage compared to the those treated with chemotherapy alone, indicating a cardioprotective role. To confirm the <em>in vivo</em> results, tumor cell lines and rat cardiomyocytes were treated with cisplatin <em>in vitro</em>, with and without A009. Another frequently used chemotherapeutic agent 5-fluorouracil (5-FU), was also tested in this assay, observing a similar effect. In vitro, the combination of A009 with cisplatin or 5-FU was effective in decreasing prostate and colon cancer cell growth, while it did not further reduce growth of rat cardiomyocytes also treated with cisplatin or 5-FU. A009 cardioprotective effects towards side effects caused by 5-FU chemotherapy were further investigated, using cardiomyocytes freshly isolated from mice pups. A009 mitigated toxicity of 5-FU on primary cultures of mouse cardiomyocytes. Our study demonstrates that the polyphenol rich purified A009 extracts enhance the effect of chemotherapy <em>in vitro</em> and <em>in vivo,</em> but mitigates chemotherpy adverse effects on heart and on isolated cardiomyocytes. Olive mill waste water extracts could therefore represent a potential candidate for cardiovascular prevention in patients undergoing cancer chemotherapy.</p>
A Survey of State Hazard Mitigation Officers About Integrating Climate Change into Hazard Mitigation Planning
<p>56 U.S. state hazard mitigation officers (SHMOs) were invited by email to participate in a brief, 25 question online survey administered through SurveyMonkey (SurveyMonkey Inc., San Mateo, CA, USA: <a href="http://www.surveymonkey.com/">www.surveymonkey.com</a>) in March & April 2018. Thirty-five (62.5%) SHMOs responded to the survey. The survey sought to assess climate change integration into state hazard mitigation plans, as well as barriers and facilitators to such integration.</p>
Gabetto et al_2024_Biochar from crop residues mitigates N2O emissions and raises carbon content in tropical soils
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CPL mitigates myeloproliferative neoplasms through dual targeting of cell senescence and NF-κB signaling
GEO Series GSE252715. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Restores Epithelial Identity and Mitigates Lung Fibrosis
GEO Series GSE311800. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
miR-17/20a mitigates interstitial fibrosis by repressing Frmd6 expression in renal epithelia
GEO Series GSE254786. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Other.
Academy of Program/Project & Engineering Leadership Orbital Debris Management and Risk Mitigation
The NASA Academy of Program/Project & Engineering Leadership (APPEL) is excited to announce the public release of Orbital Debris Management and Risk Mitigation, its first publication of NASA training materials using the iBook format.
Academy of Program/Project & Engineering Leadership Orbital Debris Management and Risk Mitigation
The NASA Academy of Program/Project & Engineering Leadership (APPEL) is excited to announce the public release of Orbital Debris Management and Risk Mitigation, its first publication of NASA training materials using the iBook format.
Academy of Program/Project & Engineering Leadership Orbital Debris Management and Risk Mitigation
The NASA Academy of Program/Project & Engineering Leadership (APPEL) is excited to announce the public release of Orbital Debris Management and Risk Mitigation, its first publication of NASA training materials using the iBook format.
Can personalized medicine mitigate confirmation bias in mental health?
<p>Can personalized medicine mitigate confirmation bias in<br> mental health? </p> <p> </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.