Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
3,947
datasets available to search
ShareScore release 0.9.0
Dataset results
3,947 results for “Requirement”
Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome
GEO Series GSE24618. Saccharomyces cerevisiae. 5 samples. Type: Genome binding/occupancy profiling by genome tiling array.
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo
GEO Series GSE128837. Homo sapiens. 179 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Natural genetic variation perturbs collaborative transcription factor binding required for enhancer selection and function
GEO Series GSE46494. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Thyroid hormone receptor alpha is required for thyroid hormone-dependent neural cell proliferation during tadpole metamorphosis
GEO Series GSE130816. Xenopus tropicalis. 12 samples. Type: Expression profiling by high throughput sequencing.
The protein U5-52K is required for T cell homeostasis by maintaining splicing efficiency
GEO Series GSE208003. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A nucleolar AAA-NTPase is required for Toxoplasma gondii division
GEO Series GSE43784. Toxoplasma gondii. 6 samples. Type: Expression profiling by array.
The histone acetyltransferase KAT6B is required for haematopoietic stem cell development and function
GEO Series GSE256039. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Fgd5 indentifies hematopoietic stem cells in the murine bone marrow is is not required for definitive hematopoiesis
GEO Series GSE56952. Mus musculus. 0 samples. Type: Third-party reanalysis; Expression profiling by array.
The catalytic activity of TET1 is required for human germ cell fate choice [bulk RNA-seq]
GEO Series GSE217541. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Cfp1 is required for gene expression dependent H3K4me3 and H3K9 acetylation in embryonic stem cells (RNA-Seq)
GEO Series GSE53489. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional coactivator MED15 is required for beta cell maturation
GEO Series GSE137145. Mus musculus. 31 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
BPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation [RNA-Seq]
GEO Series GSE65545. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
EZH2 is required for gene repression in Plasmablasts
GEO Series GSE103126. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Nodulin homeobox (NDX) is required for heterochromatin homeostasis in Arabidopsis [ChIP-seq]
GEO Series GSE201837. Arabidopsis thaliana. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ARID-DNA interactions are required for promoter occupancy by SWI/SNF
GEO Series GSE32116. Mus musculus. 12 samples. Type: Expression profiling by array.
Maturation of the 90S pre-ribosome requires Mrd1 dependent U3 snoRNA and 35S pre-rRNA structural rearrangements
GEO Series GSE106868. Saccharomyces cerevisiae. 6 samples. Type: Other.
Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation
GEO Series GSE117703. Drosophila melanogaster. 6 samples. Type: Expression profiling by high throughput sequencing.
3D genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes [HICHIP_seq]
GEO Series GSE244950. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
CTCF-dependent chromatin architecture and SUZ12/PRC2 complex recruitment are required for peripheral myelination and repair
GEO Series GSE138117. Mus musculus; Rattus norvegicus. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Growth is required for perception of water availability to pattern plant root branches
GEO Series GSE92406. Zea mays. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.