Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,880
datasets available to search
ShareScore release 0.9.0
Dataset results
2,880 results for “variant”
A Novel Functional Splice Variant of AKT3 Defined by Analysis of Alternative Splice Expression in HPV-Positive Oropharyngeal Cancers (MBD-Seq)
GEO Series GSE112023. Homo sapiens. 79 samples. Type: Methylation profiling by high throughput sequencing.
High-throughput splicing assays identify missense and silent splice-disruptive POU1F1 variants underlying pituitary hormone deficiency
GEO Series GSE172504. Homo sapiens; Chlorocebus aethiops. 18 samples. Type: Other.
A functional genomics atlas enhanced by convolutional neural networks facilitates clinical interpretation of disease relevant variants in non-coding regulatory elements [STARR-RNA-seq]
GEO Series GSE263335. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Immune transcriptome analysis of COVID-19 patients infected with SARS-CoV-2 variants carrying the E484K escape mutation identifies a distinct gene module
GEO Series GSE190680. Homo sapiens. 100 samples. Type: Expression profiling by high throughput sequencing.
A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation
GEO Series GSE162387. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation.
GEO Series GSE240712. Mus musculus. 24 samples. Type: Methylation profiling by high throughput sequencing.
Novel insights into the genetic basis and proteotranscriptomic elucidation of virulence attenuation in Pseudomonas syringae pv. actinidiae variants
GEO Series GSE286024. Pseudomonas syringae pv. actinidiae. 9 samples. Type: Expression profiling by high throughput sequencing.
Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells
GEO Series GSE117459. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Pathogenic TSC2 variants alter developmental trajectories of human cortical organoids and perturb cell-cell communication networks
GEO Series GSE247369. Homo sapiens. 92 samples. Type: Expression profiling by high throughput sequencing.
Restless Legs Syndrome-associated variant in MEIS1 confers altered gene expression in embryonic ganglionic eminences
GEO Series GSE44592. Mus musculus. 23 samples. Type: Expression profiling by array.
Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells
GEO Series GSE278450. Homo sapiens. 22 samples. Type: Expression profiling by high throughput sequencing.
The IPF-associated variant in MUC5B, rs35705950, resides within an enhancer that is subject to lineage- and disease-dependent epigenetic remodeling
GEO Series GSE161685. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Genetic Variants of Phospholipase C-γ2 Confer Altered Microglial Phenotypes and Differential Risk for Alzheimer’s Disease [bulk RNA-seq]
GEO Series GSE237493. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder [fibroblast]
GEO Series GSE301238. Homo sapiens. 69 samples. Type: Expression profiling by high throughput sequencing.
Identification of copy number variants in horses
GEO Series GSE32702. Equus caballus. 18 samples. Type: Genome variation profiling by array.
Integrative fine-mapping of regulatory variants and mechanisms at coronary artery disease loci
GEO Series GSE72696. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells [scRNA-seq]
GEO Series GSE194424. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
A human STAT3 gain of function variant drives Th17 expansion and IL-22 dependent skin inflammation in a model of psoriasiform dermatitis
GEO Series GSE240205. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Genetic Variants of Phospholipase C-γ2 Confer Altered Microglial Phenotypes and Differential Risk for Alzheimer’s Disease [snRNA-seq]
GEO Series GSE237494. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Single-cell multiomics of the human retina reveals hierarchical transcription factor collaboration in mediating cell type-specific effects of genetic variants on gene regulation
GEO Series GSE247157. Homo sapiens. 41 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.