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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
GEO Series GSE112608. Homo sapiens; Drosophila melanogaster. 111 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1 [CUT&RUN]
GEO Series GSE218301. Mus musculus. 45 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Heterochromatin rewiring and domain disruption-mediated chromatin compaction during erythropoiesis [HiChIP]
GEO Series GSE183990. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis
GEO Series GSE281472. Homo sapiens; Mus musculus. 245 samples. Type: Expression profiling by high throughput sequencing.
HNF1A regulates a β-cell RNA splicing program that is disrupted in type 2 diabetes [RNA-seq]
GEO Series GSE277551. Homo sapiens; Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Disruption of deoxynucleotide biosynthesis leads to RASproto-oncogene activation and perturbation of mitochondrial metabolism.
GEO Series GSE261897. Homo sapiens. 42 samples. Type: Expression profiling by high throughput sequencing; Other.
Circadian patterns of gene expression in the human brain and disruption in major depressive disorder [control set]
GEO Series GSE45642. Homo sapiens. 670 samples. Type: Expression profiling by array.
Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch [Hi-C]
GEO Series GSE222719. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer [RRBS]
GEO Series GSE233330. human gammaherpesvirus 4. 8 samples. Type: Methylation profiling by high throughput sequencing.
Profiling Drosophila third instar larval eye discs with disruptions in Hippo and Rbf pathways by 10X single-cell RNA-Sequencing
GEO Series GSE217380. Drosophila melanogaster. 9 samples. Type: Expression profiling by high throughput sequencing.
Protracted NP95 binding to hemimethylated DNA disrupts SETDB1-mediated proviral silencing [ChIP-seq]
GEO Series GSE77779. Mus musculus. 9 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Disruption of Ttll5/Stamp gene (Tubulin tyrosine ligase-like protein 5/SRC-1 and TIF2 associated modulatory protein gene) in male mice causes sperm malformation and infertility
GEO Series GSE45546. Mus musculus. 6 samples. Type: Expression profiling by array.
Disrupting ATF4 expression mechanisms provides an effective strategy for BRAF-targeted melanoma therapy (Drug Treatmant Series)
GEO Series GSE136613. Homo sapiens. 6 samples. Type: Expression profiling by array.
Disruption of histone methylation in developing sperm impairs offspring health transgenerationally
GEO Series GSE66052. Mus musculus. 15 samples. Type: Expression profiling by array.
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [ATAC-Seq]
GEO Series GSE254795. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
IFN-g and Androgens Synergistically Disrupt Mitochondrial Function in Murine Myocytes
GEO Series GSE211217. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Targeted disruption of Hotair leads to homeotic transformation and de-repression of imprinted genes [Microarray Analysis]
GEO Series GSE48004. Mus musculus. 6 samples. Type: Expression profiling by array.
Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function
GEO Series GSE239737. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Maternal obesity disrupts histone modifications mediated by Ezh2 and Ampk interactions and induces cell fate defects during embryonic cortical neurogenesis. [RNA-seq]
GEO Series GSE256004. Rattus norvegicus. 15 samples. Type: Expression profiling by high throughput sequencing.
Disrupted processing of long pre-mRNAs and widespread RNA missplicing are components of neuronal vulnerability from loss of nuclear TDP-43
GEO Series GSE27394. Mus musculus. 29 samples. Type: Genome binding/occupancy profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.