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18,621 results for “development;”
Data from: Thermal plasticity in development and diapause strategy in a temperate butterfly across a latitudinal gradient
<ol> <li>Trade-offs among traits are central to life-history theory and often closely linked to an organism's fitness. Understanding how these trade-offs vary among populations and across environments is therefore important to more accurately predict species' responses to future climate change. However, the extent to which responses vary across populations remains unknown because few studies investigate intraspecific differences. </li> <li>We performed a full-factorial split-brood common garden experiment to test how variation in rearing temperature affects developmental timing and other traits important for survival during diapause in the Glanville fritillary butterfly (<em>Melitaea</em> <em>cinxia</em>). Pre-diapause larvae originating from four regions across a latitudinal cline across Europe were reared at four temperatures (25, 28, 31, and 34 °C), and we used a reaction norm approach to test for evidence of genetic differentiation and variation in developmental plasticity across regions.</li> <li>We found clear signs of genetic differentiation in multiple developmental traits, as well as differences in developmental plasticity. Northern larvae entered diapause in the fourth instar when the temperatures were low, whereas southern larvae did so in the fifth instar. As a result, development time is canalized with regards to temperature in northern larvae: due to entering diapause one stage earlier, they develop fast even in the cold, whereas southern larvae always develop slower, especially at low temperatures. As a trade-off, northern larvae have a lower body mass when reared at cooler temperatures compared to southern larvae, and they show increased plasticity in diapause mass. No clear clinal patterns were found in relative fat content.</li> <li>Our results show that trade-offs between body size, development time and growth rate can vary within species living across environmental clines, possibly as a consequence of natural selection to local environmental conditions or other genetic constraints. This variation highlights the importance of recognising the context-dependency of relationships between important life-history traits and their interactions with local environments in predicting species' responses to climate change.</li> </ol>
Data for Potential feeding sites for seabirds and marine mammals reveal large conflicting areas with offshore wind energy development worldwide
<p>This dataset contains;</p> <p>1) The dataset (sample_point_data.Rdata) to develop the Structural Equation model </p> <p>2) The spatial tiff bivariate maps for small-ranged seabird and marine mammals and fish and zooplankton biomass respectively</p> <p>3) The Potential Feeding Sites likelihood map in a tiff format</p> <p>4) The global power density at 200m </p> <p>5) Dataset of risk category and corresponding values and coordinates for spatial representation</p>
Mosquito aging modulates the development, virulence and transmission potential of pathogens
<p>Host age variation is a striking source of heterogeneity that can shape the evolution and transmission dynamic of pathogens. Compared to vertebrate systems, our understanding of the impact of host age on invertebrate-pathogen interactions remains limited. We examined the influence of mosquito age on key life-history traits driving human malaria transmission. Females of <em>Anopheles coluzzii</em>, a major malaria vector, belonging to three age classes (4, 8, and 12 day-old), were experimentally infected with <em>Plasmodium falciparum</em> field isolates. Our findings revealed reduced competence in 12-day-old mosquitoes, characterized by lower oocyst/sporozoite rates and intensities compared to younger mosquitoes. Despite shorter median longevities in older age classes, infected 12-day-old mosquitoes exhibited improved survival, suggesting that the infection might act as a fountain of youth for older mosquitoes specifically. The timing of sporozoite appearance in the salivary glands remained consistent across mosquito age classes, with an extrinsic incubation period of approximately 13 days. Integrating these results into an epidemiological model revealed a lower vectorial capacity for older mosquitoes compared to younger ones, albeit still substantial due to extended longevity in the presence of infection. Considering age heterogeneity provides valuable insights for ecological and epidemiological studies, informing targeted control strategies to mitigate pathogen transmission.</p>
NEMARCO project: Dataset for the publication "Development of a new manufacturing route for NiCrSiFeB alloys by Direct Energy Deposition Laser Beam process (LMD)"
<p><strong>LMD dataset</strong></p> <p>This dataset gathers data from different parts of the Laser Metal Deposition metal Additive Manufacturing process (DED-LB). The dataset covers not only the process development data for samples manufacturing and monitored data of the melt pool size during the process, but also the metrics associated to the powder feedstock consumption, energy consumption and process efficiency.</p> <p><strong>Motivation</strong></p> <p>Nickel-based NiCrSiFeB alloy (Ni-Cr-Si-B self-fluxing family) are excellent candidates for replacing Cobalt-based alloys in aeronautical components such as sealing rings, valve seats, sliding bearing seats, etc. In this type of components, commonly manufactured by centrifugal casting and conventional processes, high temperature wear and stiffness under complex thermo-mechanical stresses cause lack of sealing and an increase in the wear rate. Metal additive manufacturing by direct laser metal deposition with powder (p-LMD) is presented as a potential manufacturing route for the complex processing of this type of alloys. This research work deals with the development of a new manufacturing route using p-LMD that ranges from the proper selection of the chemical composition for the starting powders, the development of the LMD process parameters to tackle the challenges associated to the wide solidification range and crack susceptibility of Ni-Cr-Si-B alloys, its monitoring and control, as well as the post- processing required to achieve the manufacture of aeronautical components.</p>
MERFISH on developing thalamus
<p><span>The thalamus plays a central coordinating role in the brain. Thalamic neurons are organized into spatially-distinct nuclei, but the molecular architecture of thalamic development is poorly understood, especially in humans. To begin to delineate the molecular trajectories of cell fate specification and organization in the developing human thalamus, we used single-cell and multiplexed spatial transcriptomics. Here we show that molecularly-defined thalamic neurons differentiate in the second trimester of human development and that these neurons organize into spatially and molecularly distinct nuclei. We identify major subtypes of glutamatergic neuron subtypes that are differentially enriched in anatomically distinct nuclei. In addition, we identify six subtypes of GABAergic neurons that are shared and distinct across thalamic nuclei.</span></p>
Develop protocols to manage fouling on blue mussels
<p>Aim: Develop protocols for sea-based fouling treatment on blue mussels (<em>Mytilus edulis</em>) at an industrial scale</p> <p>1) Settlement dynamics of tube worms was evaluated using field monitoring.</p> <p>2) Fouling treatments were evaluated using lab trials (in tanks) for evaluation of effects of heat treatment of fouling organisms on mussels. A range of different temperatures and exposure times were evaluated. The data consists of parameters associated with the treatments (temperature) and survival of mussels, survival of fouling organisms (especially tube worms). Data originates from the Swedish west coast and was collected during 2020-2021.</p>
Developing and testing protocols for fouling treatments on oysters
<p>Aim: Develop protocols for effective fouling treatment on oysters (Ostrea edulis and Magallana gigas) in the lab.</p> <p>Fouling treatments were evaluated using lab trials (in tanks) for evaluation of effects of heat treatment of fouling organisms on oysters. A range of different temperatures and exposure times was evaluated. The data consists of parameters associated with the treatments (temperature) and survival of oysters, survival of fouling organisms. Data originates from the Swedish west coast.</p>
Effect of culture conditions on the early stages of development of Codium tomentosum
<p>This dataset was generated by the experimental work performed to evaluate of the effect of culture conditions on the early stages of development of <em>Codium tomentosum</em> in the laboratory. The data is relevant for research on the reproduction and the development of propagation protocols for <em>C.</em> <em>tomentosum</em>.</p>
Data from: Coincident development and synchronization of sleep-dependent delta in the cortex and medulla
<p>In early development, active sleep is the predominant sleep state before it is supplanted by quiet sleep. In rats, the developmental increase in quiet sleep is accompanied by the sudden emergence of the cortical delta rhythm (0.5-4 Hz) around postnatal day 12 (P12). We sought to explain the emergence of cortical delta by assessing developmental changes in the activity of the parafacial zone (PZ), a medullary structure thought to regulate quiet sleep in adults. We recorded from PZ in P10 and P12 rats and predicted an age-related increase in neural activity during increasing periods of delta-rich cortical activity. Instead, during quiet sleep we discovered sleep-dependent rhythmic spiking activity—with intervening periods of total silence—phase-locked to a local delta rhythm. Moreover, PZ and cortical delta were coherent at P12, but not at P10. PZ delta was also phase-locked to respiration, suggesting sleep-dependent modulation of PZ activity by respiratory pacemakers in the ventral medulla. Disconnecting the main olfactory bulbs from the cortex did not diminish cortical delta, indicating that the influence of respiration on delta at this age is not mediated indirectly through nasal breathing. Finally, we observed an increase in parvalbumin-expressing terminals in PZ across these ages, supporting a role for local GABAergic inhibition in PZ's rhythmicity. The unexpected discovery of delta-rhythmic neural activity in the medulla—when cortical delta is also emerging—provides a new perspective on the brainstem's role in regulating sleep and promoting long-range functional connectivity in early development.</p>
Figure 4 in Postembryonic development of appendicular and axial skeletons in Labeo parvus (Cyprinidae)
Figure 4. - Schematic representations of the development of the vertebral column in Labeo parvus. In blue: cartilaginous structures (neural basal dorsal and haemal basal ventral arches) as observed with Alcian blue staining. In red: development of the osseous structures (neural basal dorsal arch, haemal basal ventral arch, and vertebral structure) as observed with Alizarin Red S. A: 14 days posthatching (dph); B: 19 dph; C: 24 dph; D: 29 dph.
Figure 1 in Early development of the freshwater goby Orsinogobius croaticus endemic to Croatia and Bosnia-Herzegovina
Figure 1. – Geographic distribution of the Orsinogobius croaticus. The circle indicates the sampling site.
Figure 4 in Size of nest complexes, the size of anthills, and infrastructure development in 4 species wood ants (Formica rufa, F. polyctena, F. aquilonia, F. lugubris) (Hymenoptera;
Figure 4. Average diameter (4A, 4B) and height (4C, 4D) of F. rufa and F. polyctena anthills depending on the status: single, 2-5 anthills, 6- 10 anthills, 11-20 anthills, 21-50 anthills, 51-100 anthills in the nest complex (colony). Kyiv andregion, Ukraine.
Figure 7 in Size of nest complexes, the size of anthills, and infrastructure development in 4 species wood ants (Formica rufa, F. polyctena, F. aquilonia, F. lugubris) (Hymenoptera;
Figure 7. Estimates of pair correlation function g(r) plotted against distance r for anthills of F. rufa (7A) and F.polyctena (7B).
Figure 6 in Size of nest complexes, the size of anthills, and infrastructure development in 4 species wood ants (Formica rufa, F. polyctena, F. aquilonia, F. lugubris) (Hymenoptera;
Figure 6. Average number of trails depending on the size class of the anthill F. rufa taking into account the diameter (6A) and height (6B), F. polyctena - also taking into account the diameter (6C) and height (6D), Kyiv and region, Ukraine.
Figure 5 in The detection of weakly developed plicidentine in teleost teeth using 3D tomography
Figure 5. - Dissostichus eleginoides (Nototheneidae); tomographic imaging of the anterior portion of the left premaxilla. A: Virtual model of the whole premaxilla (pmx) showing the external aspect of three caniniform teeth with external basal ridges (arrowheads); a fourth broken tooth shows ridges in the pulp cavity (white arrow); B: Virtual model of the premaxilla (bo) with axial section of the two widest caniniform teeth that show dentine folds in the pulp cavity (black arrowhead); folds are also shown in the broken tooth (white arrowhead); C: Virtual cross section in the tooth base at the level of the vascular aperture showing folds in the pulp cavity (white arrows); D: Virtual cross section, lightly above the previous level in C, showing dentine folds (white arrows) and external ridges (white arrowheads); the dentine core (de) of the tooth is perforated; E: Virtual axial section of the biggest tooth showing thin cavity and canals in the dentine (de); the tooth is covered by a thin enameloid layer; white arrowheads point to folds in the pulp cavity (pc). Scale bars: A, B = 5 mm; C, D = 2 mm; E = 1 mm.
Figure 2 in The detection of weakly developed plicidentine in teleost teeth using 3D tomography
Figure 2. - Tomographic imaging of the teeth of various teleostean taxa known to have plicidentine (see the text). A: Arapaima gigas (Arapaimatidae). Lingual dentary plate; the axially sectioned tooth (arrow) corresponds to figure 7 in Meunier et al. (2013); the tooth tip is covered by an enameloid cap (arrowheads); Inset: Virtual cross section of the base of several teeth at various levels, a number of which shows dentin folds in the pulp cavity (asterisks). B-D: Hoplias aimara (Hoplerythrinidae); right premaxilla; B: External view of a fang and a mid-sized caniniform tooth showing the basal ridges (asterisk) and the apical enameloid cap (arrow heads); C: Virtual axial section of the fang showing the folds in the pulp cavity (asterisk), the apical enameloid cap and the premaxillary bone; D: Virtual cross section of the fang (upper) and the mid-sized tooth (lower) showing regular primary folds (arrowheads) and external ridges (arrows); E-F: Lophius piscatorius (Lophiidae); tomographic image of anterior portion of the left palato-pterygoid; E: Basal ridges on the left external surface of a tooth (arrow head); on the right, pulp cavity of two teeth with obvious folds (white arrow). The black arrows point to the attachment bone (bo); F: Virtual cross section of the two teeth on the left on Fig. E; the folds are restricted to a part of the teeth. Scale bars: A, D = 1 mm; B, C, F = 2.5 mm; E = 5 mm.
Developing a Health Insurance Navigation Program for Survivors of Childhood Cancer
ClinicalTrials.gov study NCT04520061. IPD Sharing: NO. Countries: 1. Publications: 10.
Developing and Testing the Enhancing Active Caregiver Training (EnACT) Intervention for Dementia Family Caregivers
ClinicalTrials.gov study NCT04920006. IPD Sharing: YES. Countries: 1. Publications: 5.
Development and Evaluation of Virtual Reality Experiences for Cognitive Stimulation at the Sociosanitary Center El Carme
ClinicalTrials.gov study NCT06155721. IPD Sharing: NO. Countries: 1. Publications: 8.
Development of a Tailored HIV Prevention Intervention for Young Men
ClinicalTrials.gov study NCT02842060. IPD Sharing: YES. Countries: 1. Publications: 3.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.