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3,584 results for “Fibroblasts”
Large-scale analysis of longitudinal skin gene expression in systemic sclerosis reveals relationships of immune cell and fibroblast activity with skin thickness and a trend towards normalization over
GEO Series GSE181549. Homo sapiens. 339 samples. Type: Expression profiling by array.
Breaking the lineage barrier: Direct induction of trophoblast stem cells from murine fibroblasts
GEO Series GSE64339. Mus musculus. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer
GEO Series GSE267533. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Lysyl hydroxylase 2 deficiency promotes filopodia formation and fibroblast migration
GEO Series GSE186100. Mus musculus. 6 samples. Type: Expression profiling by array.
IL-17 activates dermal reticular fibroblasts to promote neutrophil recruitment and host defense [RNAseq]
GEO Series GSE230511. Mus musculus; Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.
YAP/TAZ activity in PDGFRa-expressing alveolar fibroblasts modulates lung fibroblast-epithelial cell crosstalk through Wnt4 [scATAC-seq]
GEO Series GSE291640. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Expression data of thermally eluted RNA from human primary fibroblasts with non-targeting or GLD4 siRNA treatment
GEO Series GSE77747. Homo sapiens. 6 samples. Type: Expression profiling by array.
Chromosomal status of GM00285 and GM05563 fibroblast and iPSCs
GEO Series GSE52585. Homo sapiens. 5 samples. Type: Genome variation profiling by SNP array; Genome variation profiling by genome tiling array.
RUNX1 is Expressed in a Subpopulation of Dermal Fibroblasts and is Associated with Disease Severity of Systemic Sclerosis
GEO Series GSE311858. Homo sapiens. 16 samples. Type: Methylation profiling by genome tiling array.
Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [ChIP-seq_histone]
GEO Series GSE44159. Mus musculus. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation
<p>The supplemental data for manuscript titled '<strong>TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation'.</strong></p>
Homophilic and heterophilic cadherin bond formation in fibroblast and epithelial cells-AFM based SCFS and immunofluorescence data
<p>This repository contains all the raw and processed data obtained from Atomic Force Microscopy based single-cell force spectroscopy and immunofluorescence microscopy for investigating the cadherin homophilic and heterophilic mechanical bond rupture forces, that are expressed in fibroblast and epithelial cell-cell adherens junctions.</p>
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
<p>The following folders/files are part of this repository:</p> <p> </p> <ul> <li>“List of samples” excel file: contains the list of samples used in this project</li> </ul> <p> </p> <ul> <li>CD8_ANALYSIS: contains two folders: CTRLs (control samples) and TMA (DLBCL TMA sample cores in duplicate).</li> </ul> <p>Each subfolder contains the following excel files:</p> <ul> <li>ImageNumber_legend_and_counts: excel file summarizing the image number associated to each sample, total number of CD8 and number of CD8 in contact with stroma</li> <li>Info_CP_Pipeline: cell profile pipeline used for CD8 analysis</li> <li>MyExpt_CD8_objects: raw data of all CD8</li> <li>MyExpt_CD8_on_stroma: raw data of all CD8</li> </ul> <p> </p> <ul> <li>ORIGINAL_IMAGES: it contains two folders: <ul> <li>exclusion_masks: masks used to exclude areas of the tissue from the analysis</li> <li>Original_images: spillover corrected TIFF images for each channel</li> </ul> </li> </ul> <p> </p> <ul> <li>STROMAL_CELL_ANALYSIS: <ul> <li>FRCs_Network_Shape: overlay TIFF images of the stromal network shape</li> <li>PDL1_PDL2_Stromal_Masks: TIFF images of stromal cell masks for PD-L1 and PD-L2 checkpoints expression</li> <li>Stromal_Cell_Masks: TIFF images of stromal cell masks for the three main stromal subpopulations of the lymph node (BECs, LECs, FRCs)</li> </ul> </li> </ul>
Transcriptional profiling of murine embrionic fibroblasts infected with high capacity MCMV vector.
<p><span>To gain a detailed knowledge about the virus cycle of murine cytomegalovirus (MCMV) and its high capacity vector in cross-species settings, we analyzed the early and late viral and host transcriptome upon infection of human cells. ARPE-19, A549, and 911 cells (5.0×10<sup>5 </sup>cells/well) were infected in a 24-well format 4 h post-seeding with MCMV-wt or Q4-LRBAs-GLuc, a high capacity replication competent vector based on MCMV, at an MOI of 3. As control, we used infection of mouse embryonic fibroblast, which is the natural host of the wild type MCMV, treated similarly. Harvesting occurred at 8 hpi and 31 hpi through centrifugation at 1.000 g for 5 min. Cell pellets were washed with PBS, re-suspended in 350 µL of RLT buffer, and processed using the RNeasy Mini kit as per the manufacturer’s instructions in independent triplicates. At least 1.500 ng of RNA in a 30 µL volume was isolated and sent for Illumina next-generation sequencing, resulting in paired-end sequencing with a read length of 2×100 bp and a depth of 20 million reads. This submission contains the reads, we obtained analyzing the infections of MEFs. The data sheet for the samples and the reference genomes (.gb), which we used in the analysis published in Riedl et al. Vaccines 2024 can be found in the REFERENCES_MEF.zip folder. Please, find the control reads for uninfected cells in a separate upload entitled: Mock infected controls for transcriptional profiling of infections with high capacity MCMV vector (DOI 10.5281/zenodo.1250410).</span></p>
THE OPIOID GROWTH FACTOR REDUCE ACTINE AND COLLAGEN EXPRESSION INDUCED BY TGF-β IN HUMAN FIBROBLASTS (IPF AND HEALTHY DONORS)
<p><span>Healthy lines of fibroblasts were obtained from three primary and two commercial lines of healthy lung fibroblasts, and IPF lines were obtained from lung biopsies of four IPF patients. Both groups were studied under basal conditions and following stimulation with TGF-</span><span>β</span><span>. Each experiment was performed at least three times in three lines. The OGFr, Col1a1 and </span><span>α</span><span>-SMA expression were measured by rt-qPCR, and stress actin fibers were evaluated using immunohistochemistry (phalloidin staining). The cell growth rate was <a name="_Int_iLZf8nY0"></a>determined with the WST-1 assay. </span></p>
dateset relate to article (submitted) Evaluation of mitochondrial dysfunction and idebenone responsiveness in fibroblasts from Leber's Hereditary Optic Neuropathy (LHON) subjects.
<p>raw data related to the article at title</p>
Serum Fibroblast Growth Factor-21 Levels During Prolonged Fasting
ClinicalTrials.gov study NCT05792982. IPD Sharing: NO. Countries: 1. Publications: 0.
Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2) In Gingival Recession Defects
ClinicalTrials.gov study NCT04361630. IPD Sharing: NO. Countries: 1. Publications: 0.
Correlation Between Circulating Fibroblast Activation Protein (FAP) and Fibrosis in Two Diseases (Rheumatoid Arthritis and Systemic Sclerosis)
ClinicalTrials.gov study NCT07393217. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid Filler in Human Skin
ClinicalTrials.gov study NCT06195605. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.